- Options for the management of antiviral resistance during hepatitis B therapy: reflections on battles over a decade
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Yim HJ, Hwang SG
- KMID: 1705199
- Clin Mol Hepatol.
- 2013 Sep;19(3):195-209.
- doi: 10.3350/cmh.2013.19.3.195
Although much advancement has been achieved in the treatment of chronic hepatitis B, antiviral resistance is still a challenging issue. Previous generation antiviral agents have already developed resistance in a... -
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- Comparison of tenofovir plus lamivudine versus tenofovir monotherapy in patients with lamivudine-resistant chronic hepatitis B
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Park CH, Jung SW, Shin JW, Bae MA, Lee YI, Park YT, Chung HS, Park NH
- KMID: 2363033
- Clin Mol Hepatol.
- 2016 Mar;22(1):152-159.
- doi: 10.3350/cmh.2016.22.1.152
BACKGROUND/AIMS: Tenofovir disoproxil fumarate (TDF) exhibits similar antiviral efficacy against treatment-naïve and lamivudine (LAM)-resistant chronic hepatitis B (CHB). However, there are few clinical reports on the antiviral effects of TDF-LAM... -
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- Comparison of the clinical outcomes between antiviral-naïve patients treated with entecavir and lamivudine-resistant patients receiving adefovir add-on lamivudine combination treatment
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Kim HJ, Park SK, Yang HJ, Jung YS, Park JH, Park DI, Cho YK, Sohn CI, Jeon WK, Kim BI, Choi KY
- KMID: 2373135
- Clin Mol Hepatol.
- 2016 Sep;22(3):350-358.
- doi: 10.3350/cmh.2016.0019
BACKGROUND/AIMS: To analyze the effects of preexisting lamivudine (LAM) resistance and applying antiviral treatment (adefovir [ADV] add-on LAM combination treatment) on long-term treatment outcomes, and comparing the clinical outcomes of... -
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- Efficacy and Safety of Tenofovir-Based Rescue Therapy for Chronic Hepatitis B Patients with Previous Nucleo(s/t)ide Treatment Failure
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Lee CI, Kwon SY, Kim JH, Choe WH, Lee CH, Yoon EL, Yeon JE, Byun KS, Kim YS, Kim JH
- KMID: 1774530
- Gut Liver.
- 2014 Jan;8(1):64-69.
BACKGROUND/AIMS: We investigated the efficacy and safety of tenofovir disoproxil fumarate (TDF)-based treatment in chronic hepatitis B (CHB) patients who failed previous antiviral therapies. METHODS: Seventeen patients who failed to achieve... -
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- Adefovir Dipivoxil Alone or in Combination with Ongoing Lamivudine in Patients with Decompensated Liver Disease and Lamivudine-resistant Hepatitis B Virus
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Kim KM, Choi WB, Lim YS, Lee HC, Chung YH, Lee YS, Suh DJ
- KMID: 1781766
- J Korean Med Sci.
- 2005 Oct;20(5):821-828.
- doi: 10.3346/jkms.2005.20.5.821
The purpose of this prospective study was to evaluate the efficacy and safety of adefovir dipivoxil with or without ongoing lamivudine in decompensated lamivudine-resistant chronic hepatitis B patients. Forty-six hepatitis... -
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