Skip Navigation
Skip to contents
Results by Year

View Wide

Filter

ARTICLE TYPE

PUBLICATION DATE

8 results
Display

Invertebrate Model Organisms as a Platform to Investigate Rare Human Neurological Diseases

Lee JH

Patients suffering from rare human diseases often go through a painful journey for finding a definite molecular diagnosis prerequisite of appropriate cures. With a novel variant isolated from a single...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
L-DOPA-Induced Dyskinesia in a Genetic Drosophila Model of Parkinson’s Disease

Blosser JA, Podolsky E, Lee D

  • KMID: 2506532
  • Exp Neurobiol.
  • 2020 Aug;29(4):273-284.
  • doi: 10.5607/en20028
Motor symptoms in Parkinson’s disease (PD) are directly related to the reduction of a neurotransmitter dopamine. Therefore, its precursor LDOPA became the gold standard for PD treatment. However, chronic use...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Targeted Downregulation of kdm4a Ameliorates Tau-engendered Defects in Drosophila melanogaster

Park SY, Seo J, Chun YS

BACKGROUND: Tauopathies, a class of neurodegenerative diseases that includes Alzheimer's disease (AD), are characterized by the deposition of neurofibrillary tangles composed of hyperphosphorylated tau protein in the human brain. As...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Drosophila melanogaster as a Model for Studying Aspergillus fumigatus

AL-Maliki , Martinez S, Piszczatowski P, Bennett JW

Drosophila melanogaster is a useful model organism that offers essential insights into developmental and cellular processes shared with humans, which has been adapted for large scale analysis of medically important...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Optogenetic Rescue of Locomotor Dysfunction and Dopaminergic Degeneration Caused by Alpha-Synuclein and EKO Genes

Qi C, Varga S, Oh SJ, Lee CJ, Lee D

α-Synuclein (α-Syn) is a small presynaptic protein and its mutant forms (e.g. A53T) are known to be directly associated with Parkinson's disease (PD). Pathophysiological mechanisms underlying α-Syn-mediated neurodegeneration in PD...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
The Synergistic Effects of Antimicrobial Peptides on the Growth Inhibition of Salmonella Typhimurium through Imd Pathway in Drosophila Intestine

Lim YJ, Jo YH, Kim HJ, Park JK

Some Bacillus species present in fermented foods are regarded as probiotics because of their ability to modulate the prevention of some intestinal infections and the modulation of the inflammatory immune...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Enhancement of Protein Productivity of Recombinant Hepatitis A Virus VP1 in Stably Transfected Drosophila melanogaster S2 Cells

Jeon HB, Park JH, Lee HH, Kim DH, Lee HY, Shon DH, Kim W, Chung IS

The effect of DMSO and sodium butyrate on the production of recombinant hepatitis A virus (HAV) capsid protein VP1 was evaluated and optimized in the culture of stably transfected Drosophila...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Low-dose Gamma-irradiation Effect on Early Stage Development and Lifespan in Various Strains of Drosophila melanogaster

Lee JW, Seong KM, Kim CS, Nam SY, Yang KH, Jin YW

  • KMID: 2075037
  • Korean J Occup Environ Med.
  • 2008 Sep;20(3):225-232.
OBJECTIVES: Although ionizing radiation is recognized as being harmful to humans, debate continues regarding the effects of low doses of ionizing radiation. Some studies have reported that low doses of...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close

Go to Top

Copyright © 2022 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr