- Pharmacokinetic and pharmacodynamic modeling in anesthetic field
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Han DW
- KMID: 1797465
- Anesth Pain Med.
- 2014 Apr;9(2):77-86.
Models are simplified descriptions of true biological processes. Pharmacokinetic/pharmacodynamic (PK/PD) modeling is a mathematical description on the relationship between pharmacokinetics and pharmacodynamics. The PK/PD modeling allows estimation of PK/PD parameters... -
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- Characteristics of poisoning in younger children according to different forms of the drugs
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Jang M, Ko Y, Yang HW, Lee J
- KMID: 2469719
- Pediatr Emerg Med J.
- 2019 Dec;6(2):57-62.
- doi: 10.22470/pemj.2019.00108
PURPOSE: This study aimed to investigate the characteristics of poisoning drug ingested by younger children, and to compare the clinical outcome by drug forms. METHODS: This was a retrospective analysis based... -
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- Perception and Experience of Medication Errors in Nurses with Less than One Year Job Experience
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Oh C, Yoon H
- KMID: 2177323
- J Korean Acad Fundam Nurs.
- 2007 Feb;14(1):6-17.
PURPOSE: This study was carried out to investigate perception and experience of medication errors by nurses. METHOD: Data collection through a survey was performed using structured questionnaires over the period... -
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- Omadacycline, a Magic Antibiotics for Bacterial Infections
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Rahman MS, Koh YS
- KMID: 2421306
- J Bacteriol Virol.
- 2018 Sep;48(3):109-112.
- doi: 10.4167/jbv.2018.48.3.109
Nowadays antibiotic resistance is a worldwide serious problem that mainly affects public health. Omadacycline is a unique antibiotic which has two available dosage forms such as intravenous (IV) and oral... -
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- Preclinical Pharmacokinetic Evaluation of beta-Lapachone: Characteristics of Oral Bioavailability and First-Pass Metabolism in Rats
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Kim I, Kim H, Ro J, Jo K, Karki S, Khadka P, Yun G, Lee J
- KMID: 2380341
- Biomol Ther.
- 2015 May;23(3):296-300.
- doi: 10.4062/biomolther.2015.029
beta-Lapachone has drawn increasing attention as an anti-inflammatory and anti-cancer drug. However, its oral bioavailability has not been yet assessed, which might be useful to develop efficient dosage forms possibly... -
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- Comparative Analysis of Prescription for Splitted Tablet using the HIRA-NPS (Health Insurance Review & Assessment Service-National Patient Sample)
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Kwon HJ, Jang KW, Ha D
- KMID: 2470460
- Korean J Clin Pharm.
- 2019 Dec;29(4):231-237.
- doi: 10.24304/kjcp.2019.29.4.231
OBJECTIVE: The aim of this study was to analyze the status of split tablet prescription in South Korea. METHODS: We conducted this analysis using 2016 National Patient Sample data from the... -
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- Comparison of Plasma Concentrations of Posaconazole with the Oral Suspension and Tablet in Korean Patients with Hematologic Malignancies
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Suh HJ, Kim I, Cho JY, Park SI, Yoon SH, Lee JO, Koh Y, Song KH, Choe PG, Yu KS, Kim ES, Kim HB, Bang SM, Kim NJ, Song SH, Park WB, Oh MD
- KMID: 2383935
- Infect Chemother.
- 2017 Jun;49(2):135-139.
- doi: 10.3947/ic.2017.49.2.135
The posaconazole tablet formulation was developed to have improved bioavailability compared to the oral suspension. Here, we compared posaconazole plasma concentration (PPC) with the posaconazole oral suspension versus the tablet... -
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- Establishment and Significance of Bioequivalence Recommendations for Individual Products-Drugs Acting on Circulatory System and Others
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Bae SH, Zheng YF, Kwon MJ, Choi EJ, Bae SK
- KMID: 2334541
- J Korean Soc Clin Pharmacol Ther.
- 2013 Jun;21(1):17-25.
Along with the enactment of a law separating the prescribing and dispensing of drugs in Korea in 2000, attempts at reducing medical expenses by generic substitution have been allowed since... -
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- Interactions between Medications and Nutrients in Patients Receiving Pareneteral and Enteral Nutrition
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Kim H
- KMID: 2190887
- J Korean Soc Parenter Enter Nutr.
- 2013 Aug;5(2):57-61.
- doi: 10.15747/jkspen.2013.5.2.57
Interactions between medications and nutrients are frequently known to occur in patients receiving enteral nutrition (EN) and parenteral nutrition (PN). The risk of pharmacological and nutritional interactions can be significant... -
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- Symptom and Differences in Medication Adherence in Method of Administration of Tamsulosin, Finasteride Combination Therapy in Benign Prostatic Hyperplasia
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Kim KS, Chung JH, Kim TH, Lee KS, Lee SW
- KMID: 2307831
- Korean J Urol Oncol.
- 2015 Apr;13(1):29-34.
- doi: 10.0000/kjuo.2015.13.1.29
PURPOSE: It has been reported in several for factors on the drug compliance of patients, number of drug being taken, symptom, and pharmaceutical dosage form. However, Studies of drug compliance... -
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- Effect of 5 - FU plus leucovorin for adjuvant chemotherapy according to dose related factors in colon cancer
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Shim KY, Ahn JB, Jung HC, Park JO, Yoo NC, Rha SY, Roh JK, Kim BS, Kim NK, Min JS, Chung HC
- KMID: 2080775
- Korean J Med.
- 2000 Sep;59(3):290-299.
BACKGROUND: In patients with stage C colon cancer, surgery followed by adjuvant chemotherapy with 5-fluorouracil (5-FU)/leucovorin (LV) is considered to be the standard treatment. However, the objects of... -
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- Pharmacokinetics, Pharmacodynamics and Safety of JES9501 after Single and Multiple Oral Administration in Healthy Subjects
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Kim A, Kim BH, Shin D, Cho JY, Yu KS, Jang IJ, Chung JY
- KMID: 2203227
- J Korean Soc Clin Pharmacol Ther.
- 2013 Dec;21(2):141-149.
- doi: 10.12793/jkscpt.2013.21.2.141
BACKGROUND: JES9501 is dehydroevodiamine, the extract of Evodia rutaecarpa, expected to be a new therapeutic for Alzheimer disease. This study aims to investigate the pharmacokinetics (PK), pharmacodynamics (PD) and safety... -
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