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Clinical Effect of Glutathione (Tathion) on Melasma

Han JY, Park SO, Hahm JH, Kook HI

  • KMID: 2085480
  • Korean J Dermatol.
  • 1977 Mar;15(1):57-61.
Tatbion is a tripeptide, reduced form of Glutathione(GSH or p-glutamyl-cysteiny1 -glycine). Glutathione(SH compound)is believed to inhibit melanin formation by combining witb the copper in tyrnsinase whicb is essential in the...
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Effect of UV - B Radiation on Epidermal Melanocytes of C 57BL Mouse

Kim YK, Park YK, Kim HJ

  • KMID: 2231344
  • Korean J Dermatol.
  • 1988 Apr;26(2):139-144.
This study was undertaken to investigate the effect of UVB radiation on epidermal melanoctes of C57BIL mouse, The results are summarized as follows : l) The numerical increase of DOPA...
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A Case of Acquired Bilateral Nevus of Ota-like Macules

Hong SM, Kim SN

  • KMID: 1679356
  • Korean J Dermatol.
  • 1985 Aug;23(4):543-546.
We present a case of acquired, bilateral nevus of Ota-like macules in 50-year-old women, She had deeply brownish, confluent or solitary macules and patches distributed symmetrically on the both side...
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Change of Melanocytes in Fixed Drug Eruption

Lee AY, Lee YS

  • KMID: 1930838
  • Korean J Dermatol.
  • 1989 Apr;27(2):171-176.
Lesional and normal skins in 10 patients of fixed drug eruption were studied. Number and vertical distance of rete ridges were measured in H & E stained specimens. Amount of...
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Two Cases of Oculocutaneous Albinism with Congenital Nystagmus

Han GC, Lee JH, Paik HJ

  • KMID: 2074519
  • Korean J Otolaryngol-Head Neck Surg.
  • 2004 Jul;47(7):683-691.
Albinism is a hereditary disease caused by the defect of tyrosinase that converts tyrosine to dihydroxyphenylalanine (DOPA). `Oculocutaneous albinism' is classified as hypopigmentation of skin, hair and eyes, but incidences...
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Bone Regeneration Using Block-type Deproteinized Porcine Bone Mineral with Collagen Membrane Using 3,4-Dihydroxyphenylalanine as Bone Adhesive

Kang JH, Pae HC, Cha JK, Lee JS, Paik JW, Jung UW, Choi SH

PURPOSE: The purpose of this study was to assess the adhesiveness and cytotoxicity of 3, 4-dihydroxyphenylalanine (DOPA), and to evaluate the role of collagen membrane with DOPA in the guided...
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A Case of Morphea Occuring in Vitiliginous Lesions

Kim YJ, Kim SS, Lee CJ

  • KMID: 1590966
  • Korean J Dermatol.
  • 2005 Feb;43(2):284-286.
We report a case of morphea occuring in vitiliginous lesions. About 5 months ago, two lesions of 4X4cm-sized depigmented patches appeared on her left thigh. The depigmented patches had begun...
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Effect of Repeated Ultraviolet Irradiation on Epidermal Melanocyte of the Expossed and Shielded Ear in C57BL Mice

Kim YC, Youn JI

  • KMID: 2231316
  • Korean J Dermatol.
  • 1988 Jun;26(3):283-291.
In this experiment 40 adult male C57BL mice were used. The one ear of each animal was irradiated with high pressure mercury lamp (Burdick'UV-800) and the other ear was covered...
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A Case of Acute Reticulate Hyperpigmentation on the Face and Neck

Kang H, Lee JY, Kim CW

Multiple, reticulated, dark brown colored, macules and patches suddenly developed on the fac, and neck of a 48-year-old Korean woman two days after a traffic accident. On physical examination and...
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A Study on the Effect of Various Dosage of Khellin on Epidermal Melanocytes and a Comparison with Trimethylpsoralen in Systemic Photochemotherapy

Yoon MS, Hong KT, Park YK

  • KMID: 1891652
  • Korean J Dermatol.
  • 1988 Dec;26(6):828-838.
Ninety black C 57 BL mice were divided into control and photochemotherapy groups. Control group was subdivided into a UVA 1rradiation only subgroup and a khellin only administration subgroup, while...
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Epidermal Changes with Ultraviolet Irradiation and PUVA Treatment in the Black Mouse

Han KW, Han HK, Myung KB, Kook HI

  • KMID: 2231549
  • Korean J Dermatol.
  • 1986 Oct;24(5):586-593.
The pretent study was performed to study the epiderrnal changes of ultraviolet irradiation and PUVA treatment in the black mice. The following results were obtained: 1) The histologic changes of...
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Acquired , Bilateral Nevus of Ota - like Macules : A Clinical and Histopathological Observation

Cho MH, Myung KB, Kook HI

  • KMID: 2231559
  • Korean J Dermatol.
  • 1986 Oct;24(5):645-652.
We observed the clinical and histopathologic characteristics of acquired, bilateral nevus of Ota-like macules in each 80 and 23 patients. The results were as follows: 1. All patients were female...
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The effects of PUVA on epidermal melanocytes in C57BL mice

Ree JH, Youn JI

  • KMID: 2303598
  • Korean J Dermatol.
  • 1992 Aug;30(4):484-491.
The object of this study is to evaluate the effects of repeat,ed PUVA applications on epidermal melanocytes. The changes in the number of melanocyes is compared to the frequency of...
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Quantitative Comparison of Dopa - Positve Cells in the Skin of Normal Person and Pigmentary Disorders

Oh SH, Kim YP

  • KMID: 2231630
  • Korean J Dermatol.
  • 1985 Oct;23(5):590-596.
Melanocytes were identified by the dopa reaction, and counted in vertical sections of 183 specimens of normal skin and 218 specimens of patients with pigmentary disorders. The incidence of dopa-positive...
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The Residual Motor Disability After Levodopa Supplement in Parkinsonian Patients

Sohn YH

  • KMID: 2342475
  • J Korean Neurol Assoc.
  • 1995 Jun;13(2):256-262.
It has been reported that the antiparkinsonian efficacy of levodopa is reduced after long-term administration However, main parkinsonian motor symptoms, since they are mainly caused by the deficiency of nigrostriatal...
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Flash ERG changes in Parkinson's disease: With reference to medications and clinical forms

Kim JM, Han SH, Lee KW, Lee SB, Myung HJ

  • KMID: 2184377
  • J Korean Neurol Assoc.
  • 1989 Jun;7(1):26-34.
Authors have studied photopic and scotopic flash EPGs for 19 control subjects and 20 patients with Parkinson's disease before and after various anti-Parkinsonian therapy. The following fingings were observed 1....
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The Features of Tyrosinase Expressions in Pigmentary Disorders Using TTA

Lee YK, Kim YH, Kim KH

  • KMID: 2302073
  • Korean J Dermatol.
  • 2008 Mar;46(3):325-333.
BACKGROUND: Tyrosinase is the critical enzyme in melanin synthesis. DOPA staining has been used as a standard assay for detecting tyrosinase activity, but it exhibits several limitations. Tyramide based tyrosinase...
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Effects of Gypenosides on Dopaminergic Neuronal Cell Death in 6-Hydroxydopamine-lesioned Rat Model of Parkinson's Disease with Long-term L-DOPA Treatment

Shin KS, Zhao TT, Park HJ, Kim KS, Choi HS, Lee MK

The goal of this study was to determine whether gypenosides (GPS) exert protective effects against dopaminergic neuronal cell death in a 6-hydroxydopamine (OHDA)-lesioned rat model of Parkinson's disease (PD) with...
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The effect of topical melatonin on epidermal melanocytes in uv-irradiated black mice

Lee SH, Lee JW, Burm JS, Chung CH, Oh SJ

  • KMID: 2119369
  • J Korean Soc Plast Reconstr Surg.
  • 1998 Apr;25(3):346-354.
Melatonin was derived from pineal gland, act as hormone and is known to be extremely active in certain biological systems. To observe the depigmentation effet of melatonin, author induced activation...
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Growth of Human Melanocytes in Human Epidermis Reconstructed by Culture

Cho KH, Lee DY, Yang SG, Yeo UC, Park KC, Youn JI

  • KMID: 2303468
  • Korean J Dermatol.
  • 1997 Jun;35(3):526-531.
BACKGROUND: Melanocytes grown in pure monolayer culure lack many of the cellular interactions that exist in vivo. This can be partially overcome by growing melanocytes together with other epidermal cells...
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