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Lung adenoma development and NK activity in mice treated with multiple carcinogens

Lee YS, Seo JS, Chung HT, Cho KJ, Jang JJ

A wide-spectrum initiation model was investigated in mice. Sequential treatments with diethylnitrosamine, urethane and N-methylnitrosourea, with or without a promoter, phenobarbital, resulted in tumor formation in the lungs in...
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Correlation of changes in natural killer cell activity and glutathione S-transferase placental form positive hepatocytes in diethylnitrosamine-induced rat hepatocarcinogenesis

Lee YS, Choe GY, Kim YI, Park SH, Park IA, Lee MJ, Jang JJ

To evaluate the induction of preneoplastic hepatic foci in relation to natural killer cell (NK) activity, we sequentially analyzed glutathione S-transferase placental form positive (GST-P+) hepatocytes and NK activity during ...
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Prokaryotic expression and characterization of human AP DNA endonuclease

Oh SH, Song DW, Lee MY

The expression of major human apurinic/apyrimidinic DNA endonuclease (APEX) from its cDNA in E. coli (DH5 alpha) was attempted in order to obtain a biologically active recombinant APEX....
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