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Selective Elevation of Antibodies to Desmoglein 1 during the Transition from Mucocutaneous to Cutaneous Type Pemphigus Vulgaris

Matsuda-Hirose H, Ishikawa K, Goto M, Hatano Y, Fujiwara S

No abstract available.
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The Expressions of Desmoglein 1 and 3 according to Chronologic Skin Aging

Choi YW

  • KMID: 2087377
  • Korean J Dermatol.
  • 2007 Jul;45(7):645-649.
BACKGROUND: Desmogleins are transmembrane glycoproteins of the desmosome which provide mechanical strength to epithelial tissue. Desmogleins have so far, been implicated in several diseases such as pemphigus, striate palmoplantar keratoderma,...
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Immunohistochemical Study on the Expression of Desmoglein-3 in Fetal Skin Development

Kim JB, Park HJ, Lee JS, Joh OJ, Song KY

  • KMID: 2301863
  • Korean J Dermatol.
  • 2010 Jul;48(7):558-566.
BACKGROUND: Desmogleins are calcium-dependent transmembrane glycoproteins of the desmosome that form an import component of the junction complexes of epithelial cells. Desmogleins are involved in maintaining the structural integrity of...
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Effect of Anti-CD20 Monoclonal Antibody (Rituximab) on Recalcitrant Pemphigus Vulgaris

Kim MR, Kim SC

  • KMID: 2302072
  • Korean J Dermatol.
  • 2008 Mar;46(3):319-324.
BACKGROUND: Pemphigus is a severe blistering disorder caused by autoantibodies to desmogleins 1 and 3. Because some patients with pemphigus never enter into remission, new immunosuppressants are warranted. Rituximab is...
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Pemphigus Erythematosus

Yoon J, Kim CY

  • KMID: 1447391
  • Korean J Dermatol.
  • 2011 Dec;49(12):1079-1082.
Pemphigus is a group of blistering autoimmune diseases that affect the skin and mucous membranes with autoantibodies against desmoglein. Among the pemphigus subtypes, pemphigus erythematosus is one of the rare...
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Immunolocalization of Desmoglein in Autoimmune Pemphigus

Ro YS, Lee CW, Angus B

BACKGROUND: Pemphigus foliaceus(PF) and pemphigus vulgaris(PV) have different target antigens which belong to the desmoglein(DG) subfamily of the desmosomal cadherins; DG in the case of PF and PV antigen(PVA) in...
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Expression of Desmoglein-1 in Fetal Skin Development

Kim JH, Kim EJ, Park HJ, Joh OJ, Song KY

  • KMID: 2247545
  • Korean J Dermatol.
  • 2011 Sep;49(9):786-794.
BACKGROUND: Desmosomes are cell-cell adhesion complexes that provide mechanical integrity to keratinocytes by linking them to keratin intermediate filaments. Desmosomes are composed of two major transmembrane proteins, desmoglein and desmocollin....
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Quality of Life Assessment in Korean Patients with Pemphigus

Sung JY, Roh MR, Kim SC

BACKGROUND: Measuring the quality of life (QOL) is important in the evaluation of nonclinical aspects of diseases, for the discovery of functional and psychological limitations, and in choosing treatment in...
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A Case of Pemphigus Herpetiformis with Only Immunoglobulin G Anti-Desmocollin 3 Antibodies

Hong WJ, Hashimoto , Kim SC

Pemphigus represents a group of autoimmune blistering diseases caused by autoantibodies against desmogleins (Dsgs), a class of desmosomal cadherins. Recently, several pemphigus patients only with desmocollin (Dsc) 3-specific antibodies have...
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Retinoid Induces the Degradation of Corneodesmosomes and Downregulation of Corneodesmosomal Cadherins: Implications on the Mechanism of Retinoid-induced Desquamation

Kim MY, Lee SE, Chang JY, Kim SC

  • KMID: 2383243
  • Ann Dermatol.
  • 2011 Nov;23(4):439-447.
BACKGROUND: Topical retinoids induce skin fragility. As corneodesmosomes are important adhesion structures in the epidermal cohesion, an effect of retinoids on corneodesmosomes has been suspected. OBJECTIVE: The aim of this study...
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The Effects of Calcium and Retinoic Acid on Epidermal Desmosomes

Kim SC, Won JH

  • KMID: 1930761
  • Korean J Dermatol.
  • 1994 Oct;32(5):820-831.
BACKGROUND: Desmosomes are adhesive intercellular junctions that form an important component of the junction complexes of epithelial cells. They provide intercellular links between the intermediate filament cytoskeletons of adjacent cells...
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