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Deoxycholic Acid-Induced Signal Transduction in HT-29 Cells: Role of NF-kappa B and Interleukin-8

Lee DK, Park SY, Baik SK, Kwon SO, Chung JM, Oh ES, Kim HS

  • KMID: 772624
  • Korean J Gastroenterol.
  • 2004 Mar;43(3):176-185.
BACKGROUND/AIMS: Deoxycholic acid (DCA) has been appeared to be an endogenous colon tumor promoter. In this study, we investigated whether DCA induces nuclear factor-kappa B (NF-kappa B) activation and...
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Modulation of Colon Cancer Cell Invasiveness Induced by Deoxycholic Acid

Kim HS, Lee YK, Kim JW, Baik SK, Kwon SO, Jang HI

  • KMID: 782732
  • Korean J Gastroenterol.
  • 2006 Jul;48(1):9-18.
BACKGROUND/AIMS: Deoxycholic acid (DCA), a secondary bile acid, has been implicated to promote colon cancer growth and progression. However, its molecular mechanisms are largely unknown. In this study, we investigated...
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