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Surgical Decision for Elderly Spine Deformity Patient

Kim YC, Juh HS, Lee K

Globally, the elderly population is increasing rapidly, which means that the number of deformity correction operations for elderly spine deformity patient has increased. On the other hand, for aged patients...
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Effectiveness and Safety of Tacrolimus in Patients with Active Rheumatoid Arthritis with Inadequate Response to Disease-modifying Anti-rheumatic Drugs: The TREASURE Study

Sheen DH, Hong SJ, Lee SH, Lee HS, Chung WT, Jiang H, Lee S, Yoo DH

OBJECTIVE: Evaluate effectiveness/safety of tacrolimus in patients in Korea with active rheumatoid arthritis (RA) and unsuccessful response to disease-modifying anti-rheumatic drugs (DMARDs). METHODS: Open-label, single-arm, non-comparative, 24-week, Phase-IV study in patients...
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What nutritional factors influence bone mineral density in Crohn's disease patients?

Gomes Coqueiro F, Rocha R, Menezes CA, Brasil Lopes M, Rosa Oliveira V, Fortes FM, Santana GO

BACKGROUND/AIMS: Bone mineral density (BMD) is often low in patients with Crohn's disease (CD). This study aimed to evaluate the association between nutritional factors and BMD in a group of...
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Utility of radius bone densitometry for the treatment of osteoporosis with once-weekly teriparatide therapy

Nakayama H, Toho H, Sone T

OBJECTIVES: As clinics that treat patients with osteoporosis do not usually have central dual-energy X-ray absorptiometry (DXA), bone density is often measured with radial DXA. However, no long-term evidence exists...
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Prevalence and Associated Risk Factors of Sarcopenia in Female Patients with Osteoporotic Fracture

Yoon BH, Lee JK, Choi DS, Han SH

BACKGROUND: We determined the prevalence of sarcopenia according to fracture site and evaluated the associated risk factors in female patients with osteoporotic fractures. METHODS: A total of 108 patients aged 50...
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Age-related Reference Intervals for Total Collagen-I-N-terminal Propeptide in Healthy Korean Population

Yoo JI, Park AJ, Lim YK, Kweon OJ, Choi JH, Do JH, Kim S, Kim Y, Ha YC

BACKGROUND: Procollagen type I N-terminal propeptide (PINP) is one of the most clinically useful bone formation biomarkers. Therefore, the purpose of this study was to independently evaluate the performance of...
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Effects of estradiol on HIF-1α expression and trophoblast differentiation in first trimester villous explant cultures

Cho GJ, Lee LH, Lee B, Lee J, Ahn KH, Hong SC, Kim HJ, Oh MJ

OBJECTIVE: The purpose of this study was to investigate the effects of estradiol on the expression of hypoxia-inducible factor (HIF)-1α and the differentiation of trophoblasts in human first trimester villous...
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Osteosarcopenia in Patients with Hip Fracture Is Related with High Mortality

Yoo JI, Kim H, Ha YC, Kwon HB, Koo KH

BACKGROUND: This study evaluated the prevalence of osteosarcopenia, as well as the relationship between one-year mortality and osteosarcopenia, as defined by criteria of the Asian Working Group on Sarcopenia in...
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The Treatment for Hallux Valgus with Scarf Osteotomy in Elderly Patients with Osteoporosis

Hwang SH, Lee SC, Nam CH, Baek JH, Ahn HS

PURPOSE: The aim of this study was to evaluate the radiological and clinical outcomes of scarf osteotomy for hallux valgus (HV) deformity in elderly patient with osteoporosis. MATERIALS AND METHODS: A...
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Coronary Artery Calcium Score and Bone Metabolism: A Pilot Study in Postmenopausal Women

Salari P, Keshtkar A, Shirani S, Mounesan L

BACKGROUND: Since 1991 many studies evaluated the link between cardiovascular diseases and osteoporosis, two age-related conditions, but the main common pathologic pathway has not been determined yet. The histological similarity...
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Prevalence of Osteoporosis and Effectiveness of Screening Test Using Ultrasound Bone Densitometry and Education in a Community-Dwelling Population

Kwon YJ, Park KS, Choi BH, Kim BS, Ha YC

This prospective intervention study was undertaken to estimate the prevalence and treatment rate of osteoporosis following osteoporosis screening tests in the same cohort. From November 1, 2014 to August 31,...
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Small Interfering RNA–Mediated Suppression of Fas Modulate Apoptosis and Proliferation in Rat Intervertebral Disc Cells

Park JB, Park C

STUDY DESIGN: In vitro cell culture model. PURPOSE: To investigate the effect of small interfering RNA (siRNA) on Fas expression, apoptosis, and proliferation in serum-deprived rat disc cells. OVERVIEW OF LITERATURE: Synthetic...
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Osteoporosis in East Asia: Current issues in assessment and management

Cheung EY, Tan KC, Cheung CL, Kung AW

The greatest burden of hip fractures around the world is expected to occur in East Asia, especially China. However, there is a relative paucity of information on the epidemiology and...
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Dual-Energy X-Ray Absorptiometry: Beyond Bone Mineral Density Determination

Choi YJ

Significant improvements in dual-energy X-ray absorptiometry (DXA) concerning quality, image resolution and image acquisition time have allowed the development of various functions. DXA can evaluate bone quality by indirect analysis...
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Serum Sclerostin Levels in Patients with Human Immunodeficiency Virus Infection and Their Association with Bone Turnover Markers and Bone Mineral Densitometry

Almansouri AY, Abdulfatah ME, Baaqil OH, Bakheet AA, Turki SA, Kotb MM, Althubaiti A, Almaghrabi MM, Althubaiti AM, Madani BM, Jawad AS

BACKGROUND: The aim of the study was to compare serum sclerostin levels in human im-munodeficiency virus (HIV)-infected patients and healthy controls, and to evaluate their relationship with bone turnover markers...
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Effect of RNA Interference-Mediated Suppression of p75 on the Viability of Rat Notochordal Cells

Park JB, Chang DG, Oh SY, Park EY

STUDY DESIGN: In vitro cell culture model. PURPOSE: To investigate the effects of RNA interference (RNAi) on p75 expression and viability of rat notochordal cells treated with serum deprivation. OVERVIEW OF LITERATURE:...
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Post Pregnancy Severe Spinal Osteoporosis with Multiple Vertebral Fractures and Kyphoscoliosis in a Multigravida: A Rare Case with Management

Hadgaonkar S, Shah KC, Bhatt H, Shyam A, Sancheti P

Osteoporosis associated with pregnancy and lactation is a less commonly known condition and often overlooked. The prevalence, exact aetiology and its pathogenesis are unknown. It is commonly seen in first...
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Result of Proficiency Test and Comparison of Accuracy Using a European Spine Phantom among the Three Bone Densitometries

Park AJ, Choi JH, Kang H, Park KJ, Kim HY, Kim SH, Kim DY, Park SH, Ha YC

BACKGROUND: Although dual energy X-ray absorptiometry (DXA) is known to standard equipment for bone mineral density (BMD) measurements. Different results of BMD measurement using a number of different types of...
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Percutaneous Vertebroplasty: A First Line Treatment in Traumatic Non-Osteoporotic Vertebral Compression Fractures

Elnoamany

STUDY DESIGN: This was a prospective cohort study. PURPOSE: The purpose of this study was to document and evaluate the clinical and radiological results of percutaneous vertebroplasty (PV) as a first...
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What Is the Effect of Spino-Pelvic Sagittal Parameters and Back Muscles on Osteoporotic Vertebral Fracture?

Kim DH, Choi DH, Park JH, Lee JH, Choi YS

STUDY DESIGN: Case control study. PURPOSE: To examine the effect of spino-pelvic sagittal parameters and back muscles on osteoporotic vertebral fracture. OVERVIEW OF LITERATURE: Low bone mass is not the only important...
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