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m6A Methyltransferase METTL3 Reduces Hippocampal Neuron Apoptosis in a Mouse Model of Autism Through the MALAT1/SFRP2/Wnt/β-catenin Axis

Ming Y, Deng Z, Tian X, Jia Y, Ning M, Cheng S

Objective Hippocampal neuron apoptosis contributes to autism, while METTL3 has been documented to possess great potentials in neuron apoptosis. Our study probed into the role of METTL3 in neuron apoptosis...
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Recent Advances in Cardiac Magnetic Resonance Imaging

Lee SE, Nguyen C, Xie Y, Deng Z, Zhou Z, Li D, Chang HJ

Cardiac magnetic resonance (CMR) imaging provides accurate anatomic information and advanced soft contrast, making it the reference standard for assessing cardiac volumes and systolic function. In this review, we summarize...
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Myotomy of Distal Esophagus Influences Proximal Esophageal Contraction and Upper Esophageal Sphincter Relaxation in Patients with Achalasia After Peroral Endoscopic Myotomy

Ren Y, Tang X, Chen F, Deng Z, Wu J, Nei S, Jiang B, Gong W

  • KMID: 2379706
  • J Neurogastroenterol Motil.
  • 2016 Jan;22(1):78-85.
  • doi: 10.5056/jnm15098
BACKGROUND/AIMS: The motility change after peroral endoscopic myotomy (POEM) in achalasia is currently focused on lower esophageal sphincter (LES). This study aims to investigate the correlation of motility response between...
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Human Umbilical Cord-Derived Mesenchymal Stem Cells Repair SU5416-Injured Emphysema by Inhibiting Apoptosis via Rescuing VEGF-VEGFR2-AKT Pathway in Rats

Chen Q, Lv L, Zheng C, Pan H, Xu J, Lin J, Deng Z, Qian W

Background and Objectives: Chronic obstructive pulmonary disease (COPD) is a common, frequently-occurring disease and poses a major health concern. Unfortunately, there is current no effective treatment for COPD, particularly emphysema....
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Enhancement of Gastric Ulcer Healing and Angiogenesis by Hepatocyte Growth Factor Gene Mediated by Attenuated Salmonella in Rats

Ha X, Peng J, Zhao H, Deng Z, Dong J, Fan H, Zhao Y, Li B, Feng Q, Yang Z

The present study developed an oral hepatocyte growth factor (HGF) gene therapy strategy for gastric ulcers treatment. An attenuated Salmonella typhimurium that stably expressed high HGF (named as TPH) was...
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