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Differences in age at diagnosis of ovarian cancer for each BRCA mutation type in Japan: optimal timing to carry out risk-reducing salpingo-oophorectomy

Sekine M, Enomoto T, Arai M, Den H, Nomura H, Ikeuchi T, Nakamura S, the Registration Committee of the Japanese Organization of Hereditary Breast and Ovarian Cancer

Objective BRCA1 and BRCA2 mutation carriers are recommended to undergo risk-reducing salpingo-oophorectomy (RRSO) by age 40 and 45, respectively. However, the carriers have a different way of thinking about their life...
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