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Growth Hormone-Releaser Diet Attenuates Cognitive Dysfunction in Klotho Mutant Mice via Insulin-Like Growth Factor-1 Receptor Activation in a Genetic Aging Model

Park SJ, Chung YH, Lee JH, Dang DK, Nam Y, Jeong JH, Kim YS, Nabeshima , Shin EJ, Kim HC

BACKGROUND: It has been recognized that a defect in klotho gene expression accelerates the degeneration of multiple age-sensitive traits. Accumulating evidence indicates that aging is associated with declines in cognitive...
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