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The role of tonicity responsive enhancer sites in the transcriptional regulation of human hsp70-2 in response to hypertonic stress

Heo JI, Lee MS, Kim JH, Lee JS, Kim J, Park JB, Lee JY, Han JA, Kim JI

  • KMID: 1094155
  • Exp Mol Med.
  • 2006 Jun;38(3):295-301.
The inducible 70 kDa heat shock proteins (Hsp70) in mice are encoded by two almost identical genes, hsp70.1 and hsp70.3. Studies have found that only hsp70.1 is induced by hypertonic...
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5-azacytidine induces cardiac differentiation of P19 embryonic stem cells

Choi SC, Yoon JH, Shim WJ, Ro YM, Lim DS

  • KMID: 1103318
  • Exp Mol Med.
  • 2004 Dec;36(6):515-523.
The P19 embryonal carcinoma cell line is a useful model cells for studies on cardiac differentiation. However, its low efficacy of differentiation hampers its usefulness. We investigated the effect of...
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Alterations of proliferative and differentiation potentials of human embryonic stem cells during long-term culture

Park YB, Kim YY, Oh SK, Chung SG, Ku SY, Kim SH, Choi YM, Moon SY

Human embryonic stem cells (hESCs) are considered to be able to stably maintain their characteristics in vitro for prolonged periods, but we had previously encountered changes in proliferative ability and...
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