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Methylation Pattern of DNA Repair Genes and Microsatellite Instability in Hepatocelluar Carcinoma

Park JH, Cho SB, Lee WS, Park CH, Joo YE, Kim HS, Choi SK, Rew JS, Lee JH, Kim SJ

  • KMID: 1113480
  • Korean J Gastroenterol.
  • 2006 Nov;48(5):327-336.
BACKGROUND/AIMS: Epigenetic silencing of DNA repair genes, O6-methylguanine-DNA methyltransferase (MGMT), hMLH1 and hMSH3, by promoter hypermethylation have been observed in various cancers. However, the relationship between hypermethylation of DNA...
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