- Acetoaminophen-induced accumulation of 8-oxodeoxyguanosine through reduction of Ogg1 DNA repair enzyme in C6 glioma cells
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Wan J, Bae MA, Song BJ
- KMID: 755668
- Exp Mol Med.
- 2004 Feb;36(1):71-77.
Large doses of acetaminophen (APAP) could cause oxidative stress and tissue damage through production of reactive oxygen/nitrogen (ROS/RNS) species and quinone metabolites of APAP. Although ROS/RNS are known to modify... -
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- Expression of hOGG1 protein during differentiation of HL-60 cells
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Lee YS, Lee KH, Chung MH
- KMID: 1097257
- Exp Mol Med.
- 2003 Apr;35(2):98-105.
Human 8-oxo-G-DNA glycosylase 1 (hOGG1) is a DNA glycosylase to cleave 8-oxo-7,8-dihydroguanine (8-oxo-G), a mutagenic DNA adduct formed by oxidant stresses. Here, we examined hOGG1 protein expression and repair activity... -
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