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Different protein-binding patterns in the P3 promoter region of the human insulin-like growth factor II gene in the human liver cirrhosis and hepatocellular carcinoma tissues

Seo JH, Kim KW, Park BC

The P3 promoter of the human insulin-like growth factor II (IGF-II) is the major IGF-II promoter in fetal liver (FL) and hepatocellular carcinoma (HCC). However, little information is available...
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Mechanism of Azaline B-induced Apoptosis of Ventral Prostate in Rat

Park C, Nam SI, Yun EJ, Park JI, Lee JH, Park SK, Hwang BD, Lim K

  • KMID: 2293576
  • Korean J Urol.
  • 2003 Nov;44(11):1157-1166.
PURPOSE: Androgen deprivation triggers a sequence of events that activates apoptotic cell death of the androgen-dependent epithelial cells within the rat ventral prostate, ultimately resulting in the involution of the...
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Mechanism of Castration-induced Apoptosis of Ventral Prostate in Rat

Park C, Park JI, Yun EJ, Song KS, Kim JS, Kim YR, Lee SD, Park SK, Hwang BD, Lim K

BACKGROUNDS: Castration-induced androgen deprivation triggers a sequence of events, which activates apoptotic cell death of the androgen-dependent epithelial cells within the rat ventral prostate. To investigate the mechanism of castration-dependent...
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A mechanism of differential expression of GLUT2 in hepatocyte and pancreatic beta-cell line

Kim JW, Kim YK, Ahn YH

  • KMID: 754982
  • Exp Mol Med.
  • 1998 Mar;30(1):15-20.
DNase I footprinting assay using liver nuclear extracts revealed six protected regions between nucleotide -600 and +110 and hence named Box I-VI. Upstream promoter element (UPE), a DNA element playing crucial role...
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Characterization of cis-acting elements in the rat ATP citrate-lyase gene promoter

Moon YA, Park SW, Kim KS

  • KMID: 1093599
  • Exp Mol Med.
  • 2002 Mar;34(1):60-68.
The cis-acting element in the promoter of the rat ATP-citrate lyase (ACL) and transcription factors which interact with these elements were determined. Six Sp1 binding sites and CAAT box exist...
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Characterization of regulatory elements on the promoter region of human ATP-citrate lyase

Moon YA, Kim KS, Cho UH, Yoon DJ, Park SW

  • KMID: 1029940
  • Exp Mol Med.
  • 1999 Jun;31(2):108-114.
ATP-citrate lyase (ACL), an enzyme catalyzing the first step in biosynthesis of fatty acids, is induced during the lipogenesis and cholesterologenesis. We demonstrate that the region -213 to -128 of human ACL...
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