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Study of ethidium bromide interaction peculiarities with DNA

Vardevanyan PO, Antonyan A, Manukyan G, Karapetyan AT

  • KMID: 1457531
  • Exp Mol Med.
  • 2001 Dec;33(4):205-208.
The helix-coil transition of DNA-ethidium bromide complexes in an interval of ionic strength of 2.0 x 10(-3) M < or = muNa+ < or = 2.0 x 10(-2) M has...
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Melting of complexes of DNA-cis-DDP in acidic environment

Dalyan YB, Haroutiunian TS, Haroutiunian SG, Vardevanyan PO

  • KMID: 1119335
  • Exp Mol Med.
  • 2003 Dec;35(6):534-537.
The peculiarities of helix-coil transition of DNA at complex-formation with cis-diamminedichlorplatinum (II) (cis-DDP) have been investigated in acidic environment by UV absorbance technique. It is shown that observed features of...
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The binding of ethidium bromide with DNA: interaction with single- and double-stranded structures

Vardevanyan PO, Antonyan A, Parsadanyan MA, Davtyan HG, Karapetyan AT

  • KMID: 1119334
  • Exp Mol Med.
  • 2003 Dec;35(6):527-533.
The pH-induced helix-coil transition of DNA and its complexes with EtBr is carried out at acidic pH in a wide interval of change of concentration ratio of EtBr/DNA. The binding...
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Environments of ethidium binding to allosteric Dna: II. Accessibility, mobility and mode of binding

Suh DC

  • KMID: 755100
  • Exp Mol Med.
  • 2000 Dec;32(4):204-209.
DNA binding compounds were previously shown to bind to the right-handed DNA forms and hybrid B-Z forms in a highly cooperative manner and indicate that structural specificity plays...
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Development of semi-empirical model for radiochemical reactions

Lee RJ, Suh HS

A mathematical model, which represents the radio-chemical reactions in water, was developed to study the effect of the radio-chemical products on cell kiling. The five differential equations were solved using...
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