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Association Between Polymorphisms of Ethanol-Metabolizing Enzymes and Susceptibility to Alcoholic Cirrhosis in a Korean Male Population

Lee HC, Lee HS, Jung SH, Yi SY, Jung HK, Yoon JH, Kim CY

Alcohol is oxidized to acetaldehyde by alcohol dehydrogenase (ADH) and cytochrome P-4502E1 (CYP2E1), and then to acetate by aldehyde dehydrogenase (ALDH). Polymorphisms of these ethanol-metabolizing enzymes may be associated with...
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Effects of Genetic Polymorphisms of Ethanol-Metabolizing Enzymes on Alcohol Drinking Behaviors

Kee JY, Kim MO, You IY, Chai JY, Hong ES, An SC, Kim H, Park SM, Youn SJ, Chae HB

  • KMID: 863142
  • Korean J Hepatol.
  • 2003 Jun;9(2):89-97.
BACKGROUND/AIMS: Genetic variations of ethanol-metabolizing enzymes can affect alcohol drinking behavior. The aims of this study were to investigate and compare the distributions of these genetic polymorphisms between a...
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