- Cyclooxygenase-2: A Potential Target in Human Cancer
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Won JH
- KMID: 2166143
- Cancer Res Treat.
- 2004 Jun;36(3):161-162.
No abstract available. -
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- Targeting Cyclooxygenase 2 and HER - 2 / neu Pathways Inhibits Colorectal Carcinoma Growth
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Kim YS, Kim YB, Chun HJ
- KMID: 2085000
- Korean J Gastroenterol.
- 2001 Aug;38(2):144-145.
No abstract available. -
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- Involvement of Mitogen-Activated Protein Kinase in Aspirin-induced Expression of Cyclooxygenase-2 in Amnionic Cell Line WISH Cells
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Je GH, Cha MS, Gwak JY
- KMID: 2036197
- Korean J Obstet Gynecol.
- 2000 Dec;43(12):2191-2197.
No abstract available. -
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- Effect of Anti-inflammatory Drug on the Cyclooxygenase-2 Protein Expression in Lipopolysaccharide-Stimulated Amnion Cells in Culture
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Lee PR, Jung BK, Kim SR, Kang JA, Shin MS, Won HS, Lee IS, Kim A
- KMID: 1578913
- Korean J Perinatol.
- 2000 Dec;11(4):490-497.
No abstract available. -
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- Anti-tumor mechanisms and regulation of survivin by selective cyclooxygenase-2 inhibitor
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Jang JW
- KMID: 1381460
- Korean J Hepatol.
- 2008 Sep;14(3):305-308.
- doi: 10.3350/kjhep.2008.14.3.305
No abstract available. -
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- New COX-2 Inhibitors
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Kim D, Sung YK
- KMID: 2361428
- Korean J Med.
- 2016 Dec;91(3):250-256.
- doi: 10.3904/kjm.2016.91.3.350
Nonsteroidal anti-inflammatory drugs (NSAIDs) are commonly used to treat pain and inflammation. There are two kinds of NSAID classified according to the selectivity of COX-2 inhibition: non-selective NSAIDs and cyclooxygenase... -
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- Expression of Cyclooxygenase 1 and 2 in Laryngeal Squamous Cell Carcinoma
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Kim KH, Cho KH, Lee KS, Lim DH, Paik SH, Yang HS, Hong YH, Kim MK
- KMID: 2275793
- Korean J Otolaryngol-Head Neck Surg.
- 2001 Sep;44(9):957-961.
BACKGROUND AND OBJECTIVES: A large body of evidence from a variety of experimental systems suggests that cyclooxygenase-2 (COX-2) is important in carcinogenesis. This study was to determine whether cyclooxygenase-1 (COX-1)... -
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- The Expression of Cyclooxygenase-2 and Survivin in Urinary Bladder Transitional Cell Carcinoma
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Jang TJ, Lee KS
- KMID: 1979337
- Korean J Pathol.
- 2009 Jun;43(3):206-211.
BACKGROUND: The aim of this study was to investigate the expressions of cyclooxygenase-2 (COX-2) and survivin in bladder transitional cell carcinoma (TCC) that has different clinicopathologic characteristics, and we also... -
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- Expression of cyclooxygenase-1, -2 in human uterine cervix during gestational period
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Oh JH, Kim HS, Yang JI, Kim MS, Yang SC, Han GS, Keum SS, Oh GS
- KMID: 2262123
- Korean J Obstet Gynecol.
- 2000 Nov;43(11):2014-2019.
OBJECTIVE: To determine whether cyclooxygenase (COX)-1 and COX-2 are expressed differentially during the whole gestational period in the pregnant human uterine cervix and if they are involved in the process... -
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- Cyclooxygenase - 2 Expression in Cervical Intraepithelial Neoplasia and Cervical Cancer
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Sohn WS, Kim SJ, Liu LH, Kim B, Park JY, Kang JB, Park HR, Jang PR
- KMID: 2261888
- Korean J Obstet Gynecol.
- 2000 Apr;43(4):611-615.
OBJECTIVE: A large body of evidence suggests that cyclooxygenase-2(COX-2) is important in tumorigenesis of gastrointestinal cancer. The purpose of this study was to determine whether COX-2 was also expressed in... -
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- Editor's Introduction to This Issue (G&I 15:2, 2017)
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Chung YJ
- KMID: 2384031
- Genomics Inform.
- 2017 Jun;15(2):55-55.
- doi: 10.5808/GI.2017.15.2.55
No abstract available. -
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- Renal Effects of Prostaglandins and Cyclooxygenase-2 Inhibitors
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Kim GH
- KMID: 2052304
- Electrolyte Blood Press.
- 2008 Jun;6(1):35-41.
- doi: 10.5049/EBP.2008.6.1.35
Prostaglandins (PGs) with best-defined renal functions are PGE2 and prostacyclin (PGI2). These vasodilatory PGs increase renal blood flow and glomerular filtration rate under conditions associated with decreased actual or effective... -
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- Cyclooxygenase-2 Expression in Periampullary Cancer
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Choi YJ, Jin GB, Jang LC, Park JW, Sung R, Choi JW
- KMID: 2004548
- J Korean Surg Soc.
- 2003 Jul;65(1):49-54.
PURPOSE: Cyclooxygenase-2 (COX-2) expression is up-regulated in several types of human cancers and it has been suggested that COX-2 is closely inked to carcinogenesis. The objectives of this study were... -
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- Analgesic and Anti-inflammatory Effects of Ibuprofen, Indomethacin and NS-398 on an Acute Model of Arthritis in Rats
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Kim NJ, Park JY, Han HC, Chang SH
- KMID: 1936258
- Korean J Anesthesiol.
- 2001 Jun;40(6):802-814.
- doi: 10.4097/kjae.2001.40.6.802
BACKGROUND: All currently available nonsteroidal anti-inflammatory drugs (NSAIDs) inhibit both cyclooxygenase-1 and cyclooxygenase-2 and exhibit many complications. It has been suggested that the anti-inflammatory and also most of... -
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- Peripheral Analgesic and Anti-inflammatory Effects of Diclofenac, SC-560 and NS-398 on Acute Arthritic Model in Rats
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Park HS, Park JY, Han HC, Lim HJ, Chang SH, Yoon SM
- KMID: 2236701
- Korean J Anesthesiol.
- 2004 Mar;46(3):336-341.
- doi: 10.4097/kjae.2004.46.3.336
BACKGROUND: Non-steroidal anti-inflammatory drugs (NSAIDs) are generally attributed to suppression cyclooxygenase enzymes, leading to decreased products of the arachidonic acid cascade. Since the discovery of two isoenzymes of cyclooxygenase, inhibition... -
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- Expression of Cyclooxygenase-1, -2 in Human Uterine Cervix of Preterm and Term Pregnancies
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Kim HS, Kim MS, Yang HW, Yang JI, Ahn EJ, Oh KS
- KMID: 2075714
- Korean J Obstet Gynecol.
- 1999 Apr;42(4):784-789.
OBJECTIVE: The purpose of this study was to determine whether cyclooxygenase [COX]-1 and COX-2 are expressed in the pregnant human uterine cervix and if they are expressed differentially between preterm... -
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- Physiology and pathophysiology of cyclooxygenase-2 and prostaglandin E2 in the kidney
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Norregaard R, Kwon TH, Frokiaer J
- KMID: 2381543
- Kidney Res Clin Pract.
- 2015 Dec;34(4):194-200.
- doi: 10.1016/j.krcp.2015.10.004
The cyclooxygenase (COX) enzyme system is the major pathway catalyzing the conversion of arachidonic acid into prostaglandins (PGs). PGs are lipid mediators implicated in a variety of physiological and pathophysiological... -
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- Nitric Oxide Donor, NOR-3, Increased Expression of Cyclooxygenase-2, but not of Cyclooxygenase-1 in Cultured VSMC
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Lee DH, Park JE, Kang YJ, Lee KY, Choi HC
- KMID: 2285328
- Korean J Physiol Pharmacol.
- 2006 Jun;10(3):161-165.
NO and cyclooxygenase-2 (COX-2) are contributes to vascular inflammation induced by various stimulation. The mechanism, which explains a linkage between NO and COX-2, could be of importance in promoting pathophysiological... -
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- Effects of Intravesical Instillation of Cyclooxygenase-2 Inhibitor on Cyclophosphamide-induced Overactive Bladder
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Jang J, Kim JC, Lee YB, Seo SI, Park YH, Hwang TK
- KMID: 2293233
- Korean J Urol.
- 2004 Dec;45(12):1241-1245.
PURPOSE: This study was performed to investigate the effects of intravesical instillation of cyclooxygenase-2 (COX-2) inhibitors on the cyclophosphamide-induced overactive bladder. MATERIALS AND METHODS: The 40 Sprague-Dawley rats were divided into... -
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- Expression of Cyclooxygenase-2 and Microsomal Prostaglandin E2 Synthase-1 in Human Renal Cell Carcinoma
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Cho YH, Jang TJ, Lee KS
- KMID: 2293848
- Korean J Urol.
- 2005 Oct;46(10):1057-1063.
PURPOSE: There is ample evidence suggesting an important role for cyclooxygenase-2 (COX-2) and microsomal prostaglandin E2 synthase-1 (mPGES-1) in tumorigenesis. This study aimed at evaluating the clinical significance of the... -
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