- CYCLIN D1 as a Genetic Modifier in Hereditary Nonpolyposis Colorectal Cancer
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Kim WH
- KMID: 1599443
- Korean J Gastroenterol.
- 2001 Nov;38(5):397-398.
No abstract available. -
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- Prognostic Value of p53 and Cyclin D1 in Papillary Thyroid Carcinoma
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Seok JY, Chung DH, Chung YS, Ryu JW, Lee YD
- KMID: 2144002
- Korean J Endocr Surg.
- 2015 Jun;15(2):25-33.
- doi: 10.16956/kaes.2015.15.2.25
PURPOSE: P53 and cyclin D1 have been evaluated as a prognostic marker in papillary thyroid carcinoma (PTC). However, the relationship between p53/cyclin D1 and PTC prognosis has not yet been... -
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- Significance of Expression of bcl-2, p53 and cyclin D1 and Their Correlation with Clinicopathologic Prognostic Factors and Survival Rate in 128 Cases of Invasive Breast Carcinoma
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Park SH, Lee MJ, Jeon HJ
- KMID: 1568981
- Korean J Obstet Gynecol.
- 2000 Aug;43(8):1360-1367.
No abstract available. -
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- Amplification and Overexpression of Cyclin D1 in Head and Neck Squamous Cell Carcinomas
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Kim SH, Yeom BW
- KMID: 1920908
- Korean J Otolaryngol-Head Neck Surg.
- 1997 Dec;40(12):1801-1807.
BACKGROUND: Overexpression of the cell cycle control gene, cyclin D1 may, at least in some tumor types, provide a prognostic marker. Cyclin D1 is expressed during the G1 phase of... -
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- Functional Inactivation of pRb Associated with Cyclin D1- and Cyclin-dependent Kinase 4 Overexpression Plays A Key Role in Human Pituitary Tumorigenesis
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Myong NH
- KMID: 1472555
- Korean J Pathol.
- 2009 Feb;43(1):56-62.
- doi: 10.4132/KoreanJPathol.2009.43.1.56
BACKGROUND: Human pituitary adenoma (PA) is a common intracranial tumor, but the mechanism underlying tumorigenesis has not been established. Functional inactivation of retinoblastoma protein (pRb) following cyclin D1- and cyclin-dependent... -
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- Study of the Relationships between Cyclin D1 and Known Prognostic Factors in Breast Cancer
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Kim JY, Choi YM, Kim SJ, Shin SH, Ahn SI, Woo ZH
- KMID: 2209263
- J Korean Surg Soc.
- 2000 Mar;58(3):337-344.
PURPOSE: Cyclin D1, which is known as a cell regulatory protein in G1-S phase, is overexpressed in 30-90% of breast cancers. Published data on the relationships between cyclin D1 and... -
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- Correlation between G1 Cyclins Expression and Clinical Prognostic Parameters in Endometrial Carcinoma
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Kim YT, Kim SH, Kim JW, Lee JW, Park KH
- KMID: 1615588
- Korean J Gynecol Oncol Colposc.
- 2003 Mar;14(1):30-39.
OBJECTIVE: Cyclins D1 and E play important roles in the progression of cell through G1 phase of the cell cycle. Amplification and/or overexpression of the cyclin D1 gene and aberrant... -
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- Expression of Cyclin D1 Protein in Breast Cancer and Its Correlation with Prognosis
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Han SH, Kim HY, Park KM, Lee MS, Kim HJ, Kim YD
- KMID: 2095613
- J Korean Surg Soc.
- 1999 Jun;56(6):771-776.
BACKGROUND: Cyclin D1 is known to be a key regulator in the G1 to S transition of the cell cycle in numerous cases of human neoplasia. We performed immunohistochemical assay... -
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- Expression of cyclin D1 and cyclin E in human gastric carcinoma and its clinicopathologic significance
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Ahn MJ, Kim BH, Jang SJ, Hong EK, Lee WM, Baik HK, Park HK, Lee CB, Ki M
- KMID: 645211
- J Korean Med Sci.
- 1998 Oct;13(5):513-518.
- doi: 10.3346/jkms.1998.13.5.513
Cyclin D1 and cyclin E are the mammalian G1 cydins that are both required and rate limiting for entry into S phase. Alterations in cell cycle regulators and subsequent... -
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- Expression of pRb, p16, Cyclin D1 and Cyclin E in Infiltrating Duct Carcinoma of the Breast
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Hur HK, Roh MS, Jeong JS, Rha SH, Huh GY, Hong SH
- KMID: 1725835
- Korean J Pathol.
- 2001 Oct;35(5):416-423.
BACKGROUND: Inactivation of the retinoblastoma protein (pRb) is a mechanism by which tumor cells can subdue normal growth control. Among the molecules involved in control of pRb phosphorylation, cyclin D1... -
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- Expression of p16 Protein and Cyclin D1 Protein in Head and Neck Squamous Cell Carcinomas
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Kim SH, Park SA, Oh YS
- KMID: 1559736
- Korean J Otolaryngol-Head Neck Surg.
- 1998 Jul;41(7):901-905.
BACKGROUND AND OBJECTIVES: The p16, cyclin D1, their partners Cdk4/Cdk6, and pRb constitute a G1 regulatory pathway commomly targeted in tumorigenesis. Genetical, immunochemical, and functional analyses show abnormalities of this... -
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- Expression of Cyclin D1 and bcl-2 in Infiltrative Ductal Carcinoma of the Breast: Their Correlations and Clinical implications
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Hong YK, Baik SS, Chung MS, Yoon HS
- KMID: 2286582
- J Breast Cancer.
- 2008 Dec;11(4):172-179.
- doi: 10.4048/jbc.2008.11.4.172
PURPOSE: Cyclin D1 and bcl-2 are involved in cell proliferation and apoptosis in tumor development and are commonly expressed in breast cancer. But there are few clinical reports on the... -
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- Longer Survival in Patients with Breast Cancer with Cyclin D1 Over-Expression after Tumor Recurrence: Longer, but Occupied with Disease
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Chung J, Noh H, Park KH, Choi E, Han A
- KMID: 2353083
- J Breast Cancer.
- 2014 Mar;17(1):47-53.
PURPOSE: The effect of cyclin D1 overexpression on breast cancer outcomes and prognosis is controversial, even though amplification of the cyclin D1 gene, CCND1, has been shown to be associated... -
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- The Role of E-cadherin/Beta-catenin Complex and Cyclin D1 in Head and Neck Squamous Cell Carcinoma
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Do NY, Park SY, Lim SC
- KMID: 1807310
- Cancer Res Treat.
- 2004 Feb;36(1):72-78.
PURPOSE: To determine the relationship between expression pattern of E-cadherin, Beta-catenin and cyclin D1, and clinicopathologic parameters in patients with head and neck squamous cell carcinomas (HNSCC). MATERIALS AND METHODS:... -
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- Reduced Expression of Cyclins and Proliferative Indices on the Psoriatic Epidermis after 12 Weeks of Oral Cyclosporin Therapy
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Han SS, Hyun OS, Chang SE, Lee MW, Choi JH, Moon KC, Koh JK
- KMID: 1881992
- Ann Dermatol.
- 2006 Oct;18(2):51-58.
- doi: 10.5021/ad.2006.18.2.51
Cell growth characterized by cell cycle progression is regulated by cyclin-dependent kinase (CDK). CDKs are activated by binding cyclins such as cyclin A, cyclin B, cyclin D1, and cyclin E.... -
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- Expression of Cyclin A, B1, D1, D3, and E in Non-Small Lung Cancers
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Ha SY, Kim HK, Im JS, Cho HY, Chung DH, An J
- KMID: 2199874
- J Lung Cancer.
- 2012 Jun;11(1):33-37.
- doi: 10.6058/jlc.2012.11.1.33
PURPOSE: Cyclins, and their associated cyclin dependent kinases, regulate progression of the cell cycle through the G1 phase and into the S-phase during the DNA replication process. Cyclin E regulation... -
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- Expression of p53, p21, Cycin D1, and Ki-67 in Sinonasal Tumors
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Jeong HM, Lee JH, Yun KJ
- KMID: 2131933
- J Rhinol.
- 2008 Nov;15(2):108-114.
BACKGROUND AND OBJECTIVES: The goal of this study is to investigate alterations of cell-cycle-related molecules, including p53, p21, cyclin D1 and Ki-67, in tumors arising in the sinonasal region. MATERIALS... -
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- Cyclin D1 Gene Amplification in Oral Squamous Cell Carcinoma using Differential Polymerase Chain Reaction
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Kim KS, Kim KW, Lee JH, Kim CJ
- KMID: 2005998
- J Korean Assoc Oral Maxillofac Surg.
- 2000 Aug;26(4):355-362.
Neoplastic growth is characterized by alterations of oncogenes and antioncogenes. The interaction between activated oncogenes and functional deletion of antioncogene appears to be the driving force directing normal cells to... -
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- Expression of Cyclin D1 and Bcl-xL in Basal Cell Carcinoma and Squamous Cell Carcinoma
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Kwon JI, Kim SP, Lee KS, Cho JW
- KMID: 2088180
- Korean J Dermatol.
- 2011 Mar;49(3):234-241.
BACKGROUND: Cyclin D1 has a key function in cell proliferation. Bcl-xL has anti-apoptotic effects that can protect against cell death. However, it is still largely unknown whether these proteins play... -
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- Expression of Cyclin D1 and CDK4 in DMBA-Induced Rat Ovarian Cancer
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Kim KK
- KMID: 2166233
- Cancer Res Treat.
- 2001 Jun;33(3):229-235.
PURPOSE: Ovarian cancer is a common gynecologic malignancy and the leading cause of death in women. It is typically not diagnosed until it has reached the advanced stages. We performed... -
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