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Application of Cumulus Cells as Factors to Predict the Outcome of IVF-ET

Kim KD, Kim KH, Na YJ, Lee KS

  • KMID: 1891290
  • Korean J Fertil Steril.
  • 1999 Dec;26(3):419-432.
OBJECTIVE: To establish the evaluation system of the quality of oocytes on the basis of the incidence of cumulus cells apoptosis, to investigate the relationships between the incidence of cumulus...
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Effect of cumulus cells on the development of one cell stage mouse zygotes

Han HD, Kwon JY, Han SW, Lee YJ, Cha DS, Kim DH

  • KMID: 1696583
  • Korean J Obstet Gynecol.
  • 1991 Apr;34(4):554-558.
No abstract available.
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Effect of Cumulus Cell Coculture on Early Mouse Embryonal Development in vitro

Yoo JD, Park HJ, Lee YI

  • KMID: 2261897
  • Korean J Obstet Gynecol.
  • 2000 Apr;43(4):665-669.
OBJECTIVE: To evaluate whether the rate of early mouse embryonal development could be enhanced by cumulus cell coculture in vitro. METHODS: Ham's F-10 culture media supplemented with 0.4% bovine serum albumin...
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Effects of Somatic Cell Conditioned Medium on the Chymotrypsin Resistance of Mouse Oocytes

Kim SR, Chung HW, Kim SI, Kim H

  • KMID: 2304581
  • Korean J Fertil Steril.
  • 1998 Aug;25(2):207-216.
Certain types of somatic cells, as well as follicular cumulus cells associating with mammalian oocytes, are known to produce beneficial effects on in vitro fertilization and preimplantation development of mammalian...
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Effect of Coculture System with Autologous Cumulus Cells on Embryo Quality and Pregnancy Rates

Hur EJ, Lee WK

  • KMID: 1930527
  • Korean J Fertil Steril.
  • 1998 Dec;25(3):299-304.
Despite the rapid development of assisted reproductive technologies (ART) in recent years, implantation rates after replacement of embryos into the uterine cavity remains low. Several techniques such as culture conditions...
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Differential gene expression analysis of human cumulus cells

Demiray SB, Goker EN, Tavmergen , Yilmaz O, Calimlioglu N, Soykam HO, Oktem G, Sezerman U

OBJECTIVE: This study was performed to explore the possibility that each oocyte and its surrounding cumulus cells might have different genetic expression patterns that could affect human reproduction. METHODS: Differential gene...
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Effects of Follicle Cells on the Chymotrypsin Resistance of Mouse Oocytes

Kim SI, Bae IH, Kim HK, Kim SR

  • KMID: 1891289
  • Korean J Fertil Steril.
  • 1999 Dec;26(3):407-417.
OBJECTIVE: Mammalian follicle cells are the most important somatic cells which help oocytes grow, mature and ovulate and thus are believed to provide oocytes with various functional and structural components....
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Effect of Human Cord Serum on Oocyte Maturation and Cumulus Cell Expansion

Lee YI, Park HI, Kwon YS

  • KMID: 2085099
  • Korean J Fertil Steril.
  • 1998 Apr;25(1):9-16.
This study was performed to investigate the stimulating effect on oocyte maturation and cumulus cell expansion in TC199 media by human cord serum (HCS) supplementation. Immature mouse oocyte cumulus complexes...
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Epigenetic modification of long interspersed elements-1 in cumulus cells of mature and immature oocytes from patients with polycystic ovary syndrome

Pruksananonda K, Wasinarom , Sereepapong W, Sirayapiwat P, Rattanatanyong P, Mutirangura A

OBJECTIVE: The long interspersed elements (LINE-1, L1s) are a group of genetic elements found in large numbers in the human genome that can translate into phenotype by controlling genes. Growing...
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Zona Hardening of Mouse Oocytes Undergone Meiotic Resumption In Vivo

Kim JS, Kim HK, Park JM, Lee SJ, Lee JY, Kim MK

  • KMID: 1930550
  • Korean J Fertil Steril.
  • 1997 Apr;24(1):1-11.
It is well known that the bona pellucidae of mouse oocytes become 'hardened' when they are allowed to mature in vitro in the absence of serum components. To see if...
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Autologous somatic cell nuclear transfer in pigs using recipient oocytes and donor cells from the same animal

Lee E, Song K

The objective of the present study was to examine the feasibility of the production of autologous porcine somatic cell nuclear transfer (SCNT) blastocysts using oocytes and donor cells from slaughtered...
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The Studies on the Development of Human Blastocyst Embryos in IVF-ET Program. II. The Development of Human Blastocyst Embryos by co-culture with Cumulus Cells

Lee SW, Yoon SH, Yoon HG, Cho HJ, Heo YS, Yoon HJ, Park SP, Lee WD, Lim JH

  • KMID: 2085102
  • Korean J Fertil Steril.
  • 1998 Apr;25(1):35-42.
This study was carried out to investigate the development rates of human embryos co-cultured with cumulus cells to each blastocyst stage. Human zygotes were co-cultured on cumulus cell monolayer in...
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Electron microscopy of the oocyte-cumulus complex and immuncytochemistry on the distribution of fibronectin, tenascin, and laminin

Lee YI, Cho JE, Park HJ, Kwon YS, Lee JH

  • KMID: 2261830
  • Korean J Obstet Gynecol.
  • 2000 Feb;43(2):192-202.
OBJECTIVE: Immunofluorescence microscopy including confocal laser scanning microscopy and electron microscopy were used to study the production of fibronectin, tenascin, and laminin in the cumulus-corona (CC) cells surrounding mature, unfertilized...
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Morphologic Parameters and in vitro Maturational Competence of Human Immature Oocyte Obtained from Stimulated IVF Cycle

An SJ, Jee BC, Moon JH, Lee JR, Suh CS, Kim SH

  • KMID: 1483326
  • Korean J Reprod Med.
  • 2008 Dec;35(4):285-291.
OBJECTIVE: This study was performed to investigate whether cumulus morphology and oocyte diameter influence on in vitro maturation (IVM) of human germinal vesicle (GV) stage oocytes obtained from stimulated in...
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Determination of Interleukin-1beta and Transforming Growth Factor-beta1 Levels in Early Human Embryo Coculture-Conditioned Media

Ha JW, Lee S, Hur EJ, Park JW, Lee WK

  • KMID: 2128960
  • Korean J Obstet Gynecol.
  • 1998 Oct;41(10):2571-2575.
This experiment was carried out to determine if 4~8 cell staged human embryo can produce IL-1beta and TGF-beta1, and to evaluate the probable benefit of co-culture system in the setting...
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Effect of Medicult and Human Tubal Fluid Culture Media and Cumulus Cell Coculture on Early Mouse Embryo Development in vitro

Kwon YS, Park HJ, Lee HS, Lee YI

  • KMID: 2075949
  • Korean J Obstet Gynecol.
  • 1999 Nov;42(11):2549-2557.
Objectives: This study was to evaluate whether Ham's F-10 used in assisted reproductive technology (ART) could be replaced with newly-introduced Medicult or Human Tubal Fluid (HTF) media, and the...
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In vitro Fertilization and Embryo Development in Simple Media of the Frozen-Thawed Cumulus-free Mouse Oocytes Cryopreserved by Vitrification

Jung SK, Kim SK, Lee JJ, Oh JH, Lee YH, Kim SH

  • KMID: 1566257
  • Korean J Fertil Steril.
  • 2002 Sep;29(3):201-208.
OBJECTIVE: To observe the capability of fertilization and embryo development including blastocyst formation of the oocytes in simple media after thawing of the cryopreserved cumulus-free mouse oocytes by vitrification method. METHODS:...
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Study on In Vitro Maturation and Culture of Immature Oocytes Collected from Ovaries of Infertile Women

Lee SY, Son WY, Yoon SH, Lee WD, Park CS, Lim JH

  • KMID: 2304567
  • Korean J Fertil Steril.
  • 2003 Dec;30(4):333-340.
OBJECTIVE: This study was performed to examine the maturation and the development to the blastocyst stage of immature oocytes collected from patients with high risk of ovarian hyperstimulation syndrome (OHSS). MATERIALS...
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Expession of Mullerian Inhibiting Substance in the Human Ovary

Kim JH, Kim MR, Kwon DJ, Kim JH, Rha JG, Kim SP, Kim KM, Kang CS

  • KMID: 2271641
  • Korean J Obstet Gynecol.
  • 1997 Mar;40(3):524-530.
Mullerian inhibiting substance(MIS) has been known as a non-steroidal testicular Sertolicell product responsible for the regression of Mullerian duct in male embryos. More recently MIS was also found to be...
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Improvement of Pregnancy Rates by Coculture of Human Embryos with Cumulus Cells in Glucose and Phosphate Free M-TALP Media

Chung BS, Chang WH, Lee MH, Kim JY, Bang JH, Kim KH, Suh TK

  • KMID: 2085119
  • Korean J Fertil Steril.
  • 1999 Apr;26(1):75-81.
The beneficial effect of glucose and phosphate ions in culture medium on the development of human embryos in vitro has not been fully elucidated. The purpose of this study was...
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