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Morphological and Molecular Identification of Stellantchasmus dermogenysi n. sp. (Digenea: Heterophyidae) in Thailand

Wongsawad , Nantarat N, Wongsawad , Butboonchoo P, Chai JY

We tried a series of morphological and molecular approaches to identify a new species of Stellantchasmus (Digenea: Heterophyidae) originating from the wrestling half-beaked fish, Dermogenys pusillus of Thailand. Adult worm...
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Effect of Temperature on the Killing of Opisthorchis viverrini Eggs In Vitro

Boueroy P, Duenngai K, Eamudomkarn C, Sripan P, Boonmars T, Pumhirunroj B, Artchayasawat A, Songsri J, Chomphumee K, Rattanasuwan P, Laummaunwai P, Khueangchiangkhwang S, Boonjaraspinyo S

Contaminated liver fluke egg in the environment has led to the high prevalence of human opisthorchiasis associated with cholangiocarcinoma in Southeast Asia. To find the effective lessening methods of Opisthorchis...
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The treatment effect of novel hGHRH homodimer to male infertility hamster

Zhang XD, Guo XY, Tang JX, Yue LN, Zhang JH, Liu T, Dong YX, Tang SS

Extra-hypothalamic growth hormone-releasing hormone (GHRH) plays an important role in reproduction. To study the treatment effect of Grin (a novel hGHRH homodimer), the infertility models of 85 male Chinese hamsters...
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¹²³I-Labeled oxLDL Is Widely Distributed Throughout the Whole Body in Mice

Nakano A, Kawashima , Miyake Y, Zeniya T, Yamamoto A, Koshino K, Temma T, Fukuda T, Fujita Y, Kakino A, Kanaya S, Sawamura T, Iida H

PURPOSE: Oxidized low-density lipoprotein (oxLDL) plays a key role in endothelial dysfunction, vascular inflammation, and atherogenesis. The aim of this study was to assess blood clearance and in vivo kinetics...
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Antidepressant drug paroxetine blocks the open pore of Kv3.1 potassium channel

Lee HM, Chai OH, Hahn SJ, Choi BH

In patients with epilepsy, depression is a common comorbidity but difficult to be treated because many antidepressants cause pro-convulsive effects. Thus, it is important to identify the risk of seizures...
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Chigger Mite (Acari: Trombiculidae) Survey of Rodents in Shandong Province, Northern China

Huang XD, Cheng P, Zhao YQ, Li WJ, Zhao JX, Liu HM, Kou JX, Gong MQ

Chigger mites are parasites of rodents and other vertebrates, invertebrates, and other arthropods, and are the only vectors of scrub typhus, in addition to other zoonoses. Therefore, investigating their distribution,...
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Artyfechinostomum malayanum: Metacercariae Encysted in Pila sp. Snails Purchased from Phnom Penh, Cambodia

Sohn WM, Yong TS, Eom KS, Sinuon M, Jeoung HG, Chai JY

The metacercariae of Artyfechinostomum malayanum (Leiper, 1911) Mendheim, 1943 were discovered in Pila sp. snails purchased from a market in Phnom Penh, Cambodia. They were isolated from the snails using...
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Protective Effect of an Isoflavone, Tectorigenin, Against Oxidative Stress-induced Cell Death via Catalase Activation

Zhang R, Piao MJ, Oh MC, Park JE, Shilnikova K, Moon YJ, Kim DH, Jung U, Kim IG, Hyun JW

BACKGROUND: Isoflavones are biologically active compounds that occur naturally in a variety of plants, with relatively high levels in soybean. Tectorigenin, an isoflavone, protects against hydrogen peroxide (H2O2)-induced cell damage....
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Stellantchasmus falcatus (Digenea: Heterophyidae) in Cambodia: Discovery of Metacercariae in Mullets and Recovery of Adult Flukes in an Experimental Hamster

Chai JY, Sohn WM, Na BK, Jeoung HG, Sinuon M, Socheat D

Stellantchasmus falcatus (Digenea: Heterophyidae) is first reported from Cambodia through recovery of the metacercariae from mullet fish and adult flukes from an experimentally infected hamster. We purchased 7 mullets, Chelon...
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C3H/He Mice as an Incompatible Cholangiocarcinoma Model by Clonorchis sinensis, Dicyclanil and N-Nitrosodimethylamine

Uddin MH, Li S, Jin Y, Choi MH, Jang JJ, Hong ST

Clonorchis sinensis is a Group-I bio-carcinogen, associated with cholangiocarcinoma (CCA). The hamster is the only experimental model of C. sinensis-mediated CCA, but we oblige another animal model. The present study...
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Blockade of Kv1.5 channels by the antidepressant drug sertraline

Lee HM, Hahn SJ, Choi BH

Sertraline, a selective serotonin reuptake inhibitor (SSRI), has been reported to lead to cardiac toxicity even at therapeutic doses including sudden cardiac death and ventricular arrhythmia. And in a SSRI-independent...
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Doxazosin Treatment Attenuates Carbon Tetrachloride-Induced Liver Fibrosis in Hamsters through a Decrease in Transforming Growth Factor beta Secretion

Munoz-Ortega MH, Llamas-Ramirez RW, Romero-Delgadillo NI, Elias-Flores TG, de Jesus Tavares-Rodriguez E, del Rosario Campos-Esparza M, Cervantes-Garcia D, Munoz-Fernandez L, Gerardo-Rodriguez M, Ventura-Juarez J

BACKGROUND/AIMS: The development of therapeutic strategies for the treatment of cirrhosis has become an important focus for basic and clinical researchers. Adrenergic receptor antagonists have been evaluated as antifibrotic drugs...
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Blockade of Kv1.5 by paroxetine, an antidepressant drug

Lee HM, Hahn SJ, Choi BH

Paroxetine, a selective serotonin reuptake inhibitor (SSRI), has been reported to have an effect on several ion channels including human ether-a-go-go-related gene in a SSRI-independent manner. These results suggest that...
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Induction of Spermatogenesis by Bone Marrow-derived Mesenchymal Stem Cells in Busulfan-induced Azoospermia in Hamster

Tamadon A, Mehrabani , Rahmanifar F, Jahromi AR, Panahi M, Zare S, Khodabandeh Z, Jahromi IR, Tanideh N, Dianatpour M, Ramzi M, Koohi-Hoseinabadi O

BACKGROUND: Bone marrow-derived mesenchymal stem cells (BM-MSCs) have potential of differentiation and they secrete anti-inflammatory cytokines and growth factors which make them appropriate for cell therapy. AIM OF THE WORK: Were...
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Chronic Opisthorchis viverrini Infection and Associated Hepatobiliary Disease Is Associated with Iron Loaded M2-like Macrophages

Bility MT, Sripa B

Chronic Opisthorchis viverrini-induced hepatobiliary disease is associated with significant leukocyte infiltration, including activated macrophages; however, the polarization of infiltrating macrophages remains to be fully characterized. In this study, we characterized...
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The Promoting Effect of Carbamide Peroxide Teeth Bleaching Gel in a Preclinical Model of Head and Neck Cancer in Hamster Buccal Pouch

Faccin Bampi V, Ferreira Vilela W, Vilela Goncalves R, Tavares Rheingantz MG, Minello LF, Braga da Silva JL, Oliveira de Oliveira LB

OBJECTIVES: The aim of this study was to verify the promoting effect of carbamide peroxide on dimethylbenzanthracene (DMBA)-induced carcinogenesis in the hamster buccal pouch, in order to reduce the period...
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The MAK16 Gene of Entamoeba histolytica and Its Identification in Isolates from Patients

Crisostomo-Vazquez MdP, Marevelez-Acosta VA, Flores-Luna A, Jimenez-Cardoso E

To identify sequences of Entamoeba histolytica associated with the development of amebic liver abscess (ALA) in hamsters, subtractive hybridization of cDNA from E. histolytica HM-1:IMSS under 2 growth conditions was...
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Nitric Oxide Synthase Inhibition Attenuates Cardiac Response to Hemodilution with Viscogenic Plasma Expander

Chatpun S, Cabrales P

BACKGROUND AND OBJECTIVES: Increased vascular wall shear stress by elevated plasma viscosity significantly enhances the endothelial nitric oxide synthase (eNOS) activity during an acute isovolemic hemodilution. Also the modulation of...
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Mouse Fyn induces pseudopodium formation in Chinese hamster ovary cells

An L, Liu S, Zhang W, Zhang Y, Huang Y, Hu X, Chen S, Zhao S

Molecular mechanisms underlying the effects of Fyn on cell morphology, pseudopodium movement, and cell migration were investigated. The Fyn gene was subcloned into pEGFP-N1 to produce pEGFP-N1-Fyn. Chinese hamster ovary...
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Establishment of an Allo-Transplantable Hamster Cholangiocarcinoma Cell Line and Its Application for In Vivo Screening of Anti-Cancer Drugs

Puthdee N, Vaeteewoottacharn K, Seubwai W, Wonkchalee O, Kaewkong W, Juasook A, Pinlaor S, Pairojkul , Wongkham C, Okada S, Boonmars T, Wongkham S

Opisthorchis viverrini (O. viverrini) is a well-known causative agent of cholangiocarcinoma (CCA) in humans. CCA is very resistant to chemotherapy and is frequently fatal. To understand the pathogenesis of CCA...
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