- Tracer Accumulation in Relation to Venous Thrombus on ¹â¸F-DOPA PET/CT in a Case of Persistent Hyperinsulinemic Hypoglycemia of Infancy
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Arora S, Damle NA, Passah A, Sharma R, Goyal H, Arunraj ST, Gupta P, Jana M
- KMID: 2448103
- Nucl Med Mol Imaging.
- 2019 Apr;53(2):148-151.
- doi: 10.1007/s13139-018-00568-5
¹â¸F-DOPA PET/CT is commonly done in patients with persistent hyperinsulinemic hypoglycemia of infancy (PHHI) to look for any focal lesion in the pancreas.We present the findings in a 20-day-old neonate... -
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- Images from ¹â¸F-DOPA Scan in Congenital Hyperinsulinism: Not Always a Clue for Diagnosis
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Maines E, Giacomello L, D'Onofrio , Salgarello M, Gaudino R, Baggio L, Bordugo A
- KMID: 2403513
- Nucl Med Mol Imaging.
- 2017 Dec;51(4):362-363.
- doi: 10.1007/s13139-016-0434-9
Congenital hyperinsulinism (CHI) is the most common cause of persistent hypoglycaemia in childhood (Horm Res 70:65-72, 2008; J Clin Endocr Metab 93:869-875, 2008). ¹â¸â»Fluoro-L-dihydroxy-phenylalanine (¹â¸F-DOPA) positron emission tomography (PET) can... -
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- Congenital hyperinsulinism: diagnostic and management challenges in a developing country – case report
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John CM, Agarwal P, Govindarajulu S, Sundaram S, Senniappan S
- KMID: 2400785
- Ann Pediatr Endocrinol Metab.
- 2017 Dec;22(4):272-275.
- doi: 10.6065/apem.2017.22.4.272
Management of congenital hyperinsulinemia of infancy (CHI) is challenging. A 4-month-old female infant with persistent hypoglycemia and elevated insulin levels was diagnosed with CHI. Gallium-68 DOTANOC positron emission tomography/computed tomography... -
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- A novel mutation of ABCC8 gene in a patient with diazoxide-unresponsive congenital hyperinsulinism
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Park JS, Lee HJ, Park CH
- KMID: 2362271
- Korean J Pediatr.
- 2016 Nov;59(Suppl 1):S116-S120.
- doi: 10.3345/kjp.2016.59.11.S116
Congenital hyperinsulinism (CHI) is a rare condition that can cause irreversible brain damage during the neonatal period owing to the associated hypoglycemia. Hypoglycemia in CHI occurs secondary to the dysregulation... -
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- A Case of 2-Month-Old Infant with Persistent Hyperinsulinemic Hypoglycemia Presenting as Atonic Seizure
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Kim JW, Kim DH, Kim SS
- KMID: 1910339
- Soonchunhyang Med Sci.
- 2014 Jun;20(1):56-59.
Congenital hyperinsulinism is the most frequent cause of severe, persistent hypoglycemia in infancy and childhood. It is caused by an inappropriate insulin secretion from the pancreatic beta-cells secondary to various... -
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- Congenital hyperinsulinism: current status and future perspectives
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Yorifuji T
- KMID: 1803855
- Ann Pediatr Endocrinol Metab.
- 2014 Jun;19(2):57-68.
- doi: 10.6065/apem.2014.19.2.57
The diagnosis and treatment of congenital hyperinsulinism (CHI) have made a remarkable progress over the past 20 years and, currently, it is relatively rare to see patients who are left... -
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- A Case of Persistent Hyperinsulinemic Hypoglycemia Treated with Diazoxide
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Kim MS, Park EH, Kim SY, Lee DY
- KMID: 1520749
- J Korean Soc Pediatr Endocrinol.
- 2007 Dec;12(2):164-167.
Congenital hyperinsulinism (CHI), the most important cause of hyperglycemia in early infancy, is a heterogenous disease characterized by dysregulation of insulin secretion. Mutations in five proteins have been associated with... -
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- Clinical Outcome after Pancreatectomy in Patients with Persistent Hyperinsulinemic Hypoglycemia of Infancy
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Jung MH, Hwang JS, Shin CH, Yang SW, Chi JG
- KMID: 2001523
- J Korean Soc Pediatr Endocrinol.
- 2000 Dec;5(2):171-181.
PURPOSE: The purpose of this study was to describe the clinical outcome after pancreatcetmy and its relationship with pathological appearances and clinical features in patients with persistent hyperinsulinemic hypoglycemia of... -
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- Medical Therapy in Children with Persistent Hyperinsulinemic Hypoglycemia of Infancy(PHHI)
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Kim HJ, Kim MJ, Shin HS, Kim JS, Uhm MR, Ko SH, Lee SH, Jin DK
- KMID: 2207677
- J Korean Pediatr Soc.
- 2000 Feb;43(2):253-259.
PURPOSE: Persistent hyperinsulinemic hypoglycemia of infancy(PHHI), which is characterised by inappropriate insulin secretion in spite of hypoglycemia, needs urgent treatment to prevent cerebral hypoglycemic damage. Although pancreatectomy is the treatment... -
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- Nesidioblastosis in Neonate with Persistent Hyperinsulinemic Hypoglycemia
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Whang IT, Kim HS, Han HS
- KMID: 2193882
- J Korean Soc Pediatr Endocrinol.
- 1998 Nov;3(2):231-236.
Nesidioblastosis, also known as persistent hyperinsulinemic hypoglycemia of infancy(PHHI) or familial hyperinsulinsm, is the most common cause of recurrent severe hypoglycemia in infancy. It is an autosomal recessive disorder characterized... -
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- Diffuse Nesidioblastosis of the Pancreasin Adult with Persistent Hyperinsulinemic Hypoglycemia
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Lee SH, Hyoung KY, Seo GS, Shin BJ, Cho CG, Yang KS, Chae KM, Yun KJ
- KMID: 2461629
- J Korean Soc Endocrinol.
- 1996 Jun;11(2):247-253.
Nesidioblastosis is a term that describes multifocal hyperplasia of all panereatic cell components and is characterized primarily by their disorganization and proliferation throughout the entire panaeas. Adult onset nesidioblastosis is... -
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