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Which prognostic factors are important for long-term outcomes in symptomatic obstructive colon cancer? A multi-institutional retrospective cohort study

Kim CH, Bae JH, Lee CS, Han SR, Lee IK, Lee D, Kang WK, Kim JH, Kye BH, Cho HM, Oh ST, Lee SC, Lee YS

Purpose: The prognostic factors in obstructive colon cancer have not been clearly identified. We aimed to identify the prognostic factor to establish optimal treatment strategy in obstructive colon cancer. Methods: Patients...
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Comparison of Short-term Results after Laparoscopic Complete Mesocolic Excision and Standard Colectomy for Right-Sided Colon Cancer: Analysis of a Western Center Cohort

Conti C, Pedrazzani C, Turri G, Fernandes E, Lazzarini E, De Luca R, Valdegamberi A, Ruzzenente A, Guglielmi A

Purpose: Laparoscopic complete mesocolic excision (CME) right colectomy is a technically demanding procedure infrequently employed in Western centers. This retrospective cohort study aims to analyze the safety of laparoscopic CME...
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The Impact of Primary Tumor Resection on Survival in Asymptomatic Colorectal Cancer Patients With Unresectable Metastases

Doah KY, Shin US, Jeon BH, Cho SS, Moon SM

Purpose: This study was conducted to evaluate the effectiveness of primary tumor resection (PTR) in asymptomatic colorectal cancer (CRC) patients with unresectable metastases using the inverse probability of treatment weighting...
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Risk factors of advanced metachronous neoplasms in surveillance after colon cancer resection

Nam K, Shin JE

Background/Aims: Regular surveillance colonoscopy after colon cancer resection is recommended for detecting metachronous adenoma and cancer. However, risk factors for metachronous neoplasms have not been fully evaluated. We aimed to...
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How successful is liver resection for colorectal cancer liver metastases in patients over 75 years old?

Mowbray NG, Chin C, Duncan P, O’Reilly D, Kaposztas Z, Junnarkar S, Kumar N

Backgrounds/Aims: As populations age, an increased incidence of colorectal cancer will generate an increase in colorectal cancer liver metastases (CRLM). In order to guide treatment decisions, this study aimed to...
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Prognostic Factor and Survival Benefit of Adjuvant Chemotherapy in Stage IIA Colon Cancer

Lee MW, Kim JS, Kim JY, Lee Kh

Purpose: There is no clear evidence of the benefit of adjuvant chemotherapy (AC) in stage IIA colon cancer. Therefore, we aimed to evaluate the prognostic factors and survival benefit of...
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Surgical Risk and Pathological Results of Emergency Resection in the Treatment of Acutely Obstructing Colorectal Cancers: A Retrospective Cohort Study

Tebala GD, Mingoli A, Natili A, Khan AQ, Brachini G

Purpose: The treatment of acutely obstructing colorectal cancers is still a matter of debate. The prevailing opinion is that an immediate resection should be performed whenever possible. This study sought...
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Prognostic value of carcinoembryonic antigen levels before and after curative surgery in colon cancer patients

Kim HR, Joo JI, Lim SW, Oh BY

Purpose: CEA is a useful tumor marker for colon cancer. The aim of this study was to investigate the prognostic value of changes in CEA levels before and after surgery...
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Colon Capsule Endoscopy: Indications, Findings, and Complications – Data from a Prospective German Colon Capsule Registry Trial (DEKOR)

Hausmann J, Tal A, Gomer A, Philipper M, Moog G, Hohn H, Hesselbarth N, Plass H, Albert J, Finkelmeier F

Background/Aims: Reliable and especially widely accepted preventive measures are crucial to further reduce the incidence of colorectal cancer (CRC). Colon capsule endoscopy (CCE) might increase the screening numbers among patients...
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Next-generation sequencing analysis of exosomal microRNAs: Fusobacterium nucleatum regulates the expression profiling of exosomal microRNAs in human colorectal cancer cells

Yu MR, Kim HJ, Kang JW, Kim YH, Park HR

Colon cancer is one of the most common malignant tumors, but there are still a few validated biomarkers of colon cancer. Exosome-mediated microRNAs (miRNAs) have been recognized as potential biomarkers...
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Clinical impact of sarcopenia in patients with colon cancer undergoing laparoscopic surgery

Oh RK, Ko HM, Lee JE, Lee KH, Kim JY, Kim JS

Purpose: Previous studies have reported that progressive muscle loss, known as sarcopenia, has a negative impact on colon cancer treatment. However, the majority of studies have analyzed on patients undergoing...
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‘Radial force’ of colonic stents: A parameter without consistency, definition or standard

Laasch HU, Milward GD, Edwards DW

Background: To investigate the expansion force of current colonic stents and to match these to industry standards. Methods: Samples of all colonic stents were requested from manufactures world-wide. Expansion forces were...
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Clinical characteristics and oncologic outcomes in patients with preoperative clinical T3 and T4 colon cancer who were staged as pathologic T3

Choo JM, Baek SJ, Kwak JM, Kim J, Kim SH

Purpose: Clinically suspected T4 stage colon cancer from a preoperative exam is often diagnosed as T3 stage colon cancer pathologically after surgery, raising concerns about understaging. The aims of this...
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Clinical study of colorectal cancer operation: Survival analysis

Hong Y, Kim J, Choi YJ, Kang JG

Purpose: Overall 5-year survival rates for colon and rectal cancer reported recently by the American Cancer Society were 89%, 90% for localized disease, 71%, 71% for regional disease, and 14%,...
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Cause-of-death statistics in 2018 in the Republic of Korea

Vital Statistics Division, Statistics Korea, Shin HY, Kim J, Lee S, Park MS, Park S, Huh S

This study aimed to present and analyze the causes of death in the Korean population in 2018 through an analysis of cause-of-death data from Statistics Korea, which are classified based...
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Current Colorectal Cancer in Thailand

Lohsiriwat V, Chaisomboon N, Pattana-Arun J, for the Society of Colorectal Surgeons of Thailand

This article aimed to summarize the current status of colorectal cancer (CRC) in Thailand. In brief, CRC is the third most common cancer and accounts for 11% of the cancer...
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Helicobacter pylori and Other Gastrointestinal Diseases

Park JK

Helicobacter pylori (H. pylori) is the most prevalent bacterial pathogen that infects approximately half of the world’s population. It is well known that H. pylori causes chronic gastritis, peptic ulcer,...
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Is platelet-rich plasma improves the anastomotic healing in hyperthermic intraperitoneal chemotherapy with oxaliplatin: an experimental rat study

Buk OF, Ocak S, Genc B, Avcı B, Uzuner HO

PURPOSE: Hyperthermic intraperitoneal chemotherapy (HIPEC) is a novel treatment option for peritoneal surface malignancies. Due to cytotoxic effects of chemotherapeutic agents, anastomosis healing can be impaired and lead to leakage...
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Colon Cancer Risk of a Westernized Diet Is Reduced in Mice by Feeding Cruciferous or Apiaceous Vegetables at a Lower Dose of Carcinogen but Not a Higher Dose

Kim S, Abernathy BE, Trudo SP, Gallaher DD

Western-style diets (WD) are associated with greater risk of colon cancer. Exposure to 2-amino-1-methyl-6-phenylimidazo(4,5-b) pyridine (PhIP), a food-borne carcinogen, is linked to increased colon cancer risk. In contrast, intake of...
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Identification of Risk Factors Associated With Stage III Disease in Nonmetastatic Colon Cancer: Results From a Prospective National Cohort Study

Lykke J, Roikjaer O, Jess P, Rosenberg J, On behalf of the Danish Colorectal Cancer Group

Purpose: This study aimed to identify possible patient- and tumor-related factors associated with risk of TNM stage III disease in nonmetastatic colon cancer. Methods: The associations between stage III disease and...
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