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Role of tissue inhibitors of metalloproteinases (TIMPs) in colorectal carcinoma

Joo YE, Seo KS, Kim J, Kim HS, Rew JS, Park CS, Kim SJ

Increased production of matrix metalloproteinases (MMPs) has been associated with increases in invasive and metastatic potential in many types of human carcinoma. Tissue inhibitors of metalloproteinase (TIMP)-1 inhibits most interstitial...
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Interferon-gamma upregulates the stromelysin-1 gene expression by human skin fibroblasts in culture

Lee KS, Ryoo YW, Song JY

  • KMID: 754989
  • Exp Mol Med.
  • 1998 Jun;30(2):59-64.
The equilibrium between deposition and degradation of extracellular matrix(ECM) is essential to normal tissue development and repair of wound or inflammatory responses. It has recently become apparent that several cytokines and growth factors...
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