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Control of clonorchiasis by repeated treatments with praziquantel

Hong ST, Rim HJ, Min DY, Li X, Xu J, Feng Z, Lee SH

The present study aimed to evaluate control efficacy of clonorchiasis by two schemes of repeated treatment with praziquantel at two endemic villages in China. Residents of one village at Guangxi...
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Influencing Factors for Cure of Clonorchiasis by Praziquantel Therapy: Infection Burden and CYP3A5 Gene Polymorphism

Kim CH, Lee JK, Chung BS, Li S, Choi MH, Hong ST

Chemotherapy of clonorchiasis with praziquantel (PZQ) is effective but about 15% of treated cases have been reported uncured. The present study investigated correlation of single nucleotide polymorphisms (SNPs) of the...
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Therapeutic evaluation of sustained-releasing praziquantel (SRP) for clonorchiasis: Phase 1 and 2 clinical studies

Choi MH, Chang BC, Lee SJ, Jang IJ, Shin SG, Kho WG, Chun JH, Hong ST

Sustained-releasing praziquantel (SRP) tablet was designed for single dose treatment regimen of clonorchiasis. A previous pre-clinical study confirmed its sustained-releasing characteristics and a better cure rate than conventional praziquantel (PZQ)....
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Collection of Clonorchis sinensis adult worms from infected humans after praziquantel treatment

Shen C, Kim JH, Lee JK, Bae YM, Choi MH, Oh JK, Lim MK, Shin HR, Hong ST

A cohort was established for evaluation of cancer risk factors in Sancheong-gun, Gyeongsangnam-do, Korea. As one of the cohort studies, stools of 947 residents (403 males and 544 females, age...
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