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Looking Forward to Advance of CPN to the Next Level

Pae CU

  • KMID: 2553605
  • Clin Psychopharmacol Neurosci.
  • 2024 Feb;22(1):1-1.
  • doi: 10.9758/cpn.24.001
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Two Cases of Posttraumatic Stress Disorder Caused by a Motor Vehicle Accident Treated with Virtual Reality Exposure Therapy

Kim JW, Jhon M, Kang HJ, Kim SW, Kim JM

  • KMID: 2553625
  • Clin Psychopharmacol Neurosci.
  • 2024 Feb;22(1):194-199.
  • doi: 10.9758/cpn.22.1036
Exposure-response prevention is an effective approach to treat anxiety disorders. Virtual reality exposure therapy (VRET) is a promising treatment for patients with posttraumatic stress disorder (PTSD). New research has helped...
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Vagus Nerves Stimulation: Clinical Implication and Practical Issue as a Neuropsychiatric Treatment

Jung B, Yang C, Lee SH

Vagus nerve stimulation (VNS) has been approved as an adjunctive treatment for epilepsy and depression. As the progress of VNS treatment for these neuropsychiatric disorders continues, its applications have expanded...
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Psilocybin, an Effective Treatment for Major Depressive Disorder in Adults - A Systematic Review

Watford T, Masood N

Psilocybin is a classical psychedelic which has been utilised for healing purposes for millenia. However, with its classification as a Schedule I substance, research into this compound is scarce with...
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Non-suicidal Self-injury and Quantified Electroencephalogram in Adolescents and Young Adults with Depression

Hong SY, Park YM, Park EJ

  • KMID: 2553620
  • Clin Psychopharmacol Neurosci.
  • 2024 Feb;22(1):151-158.
  • doi: 10.9758/cpn.23.1088
Objective: This study investigated the association between non-suicidal self-injury (NSSI) and quantified electroencephalogram (QEEG) in patients with depression. We aimed to identify clinical features of NSSI and differences in QEEG...
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Exploring Clinical Subgroups of Participants with Major Depressive Disorder that may Benefit from Adjunctive Minocycline Treatment

Anmella G, Meehan A, Ashton M, Mohebbi M, Fico G, Ng CH, Maes M, Berk L, Prisco MD, Singh AB, Malhi GS, Berk M, Dodd S, Hidalgo-Mazzei D, Grande I, Pacchiarotti I, Murru A, Vieta E, Dean OM

Objective: To explore illness-related factors in patients with major depressive disorder (MDD) recipients of adjunctive minocycline (200 mg/day) treatment. The analysis included participants experiencing MDD from a 12-week, double blind,...
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Efficacy and Safety of Anti-CGRP Monoclonal Antibodies in Prevention of Chronic Migraine: A Bayesian Network Meta-analysis

Haridas MP, Tripathy A, Maiti R, Srinivasan A

Due to the unmet needs in the management of migraine, a primary headache, and disabling disorder, the past decade has focused on developing monoclonal antibodies (mAbs) against the calcitonin-gene-related peptide...
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Safety and Efficacy of an Intensified and Repeated Transcranial Direct Current Stimulation Targeting Supplementary Motor Area and Dorsolateral Prefrontal Cortex in Trichotillomania (Hair Pulling Disorder): A Case Report

Alizadehgoradel J, Pouresmali A, Taherifard M

  • KMID: 2553624
  • Clin Psychopharmacol Neurosci.
  • 2024 Feb;22(1):188-193.
  • doi: 10.9758/cpn.23.1082
Trichotillomania (or hair pulling disorder) is a habitual condition in which patients constantly pull their hair. Although psychotherapies such as behavioral therapy and pharmacotherapy have shown relative effectiveness for trichotillomania,...
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Use of Serum Biomarkers to Aid Antidepressant Selection in Depressive Patients

Kang HJ, Kim JW, Choi W, Lee JY, Kim SW, Shin IS, Kim JM

  • KMID: 2553623
  • Clin Psychopharmacol Neurosci.
  • 2024 Feb;22(1):182-187.
  • doi: 10.9758/cpn.23.1071
Objective: This study aimed to identify serum biomarkers prospectively associated with remission at 12 weeks in outpatients with depressive disorders receiving stepwise psychopharmacotherapy, according to the main antidepressant used during...
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The Effect of Mobile Neurofeedback Training in Children with Attention Deficit Hyperactivity Disorder: A Randomized Controlled Trial

Kwon SY, Seo G, Jang M, Shin H, Choi W, Lim YB, Shin MS, Kim BN

Objective: To examine the effect of mobile neurofeedback training on the clinical symptoms, attention abilities, and execution functions of children with attention deficit hyperactivity disorder (ADHD). Methods: The participants were 74...
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Role of Glutamate Receptor-related Biomarkers in the Etiopathogenesis of ADHD

Ulu E, Demirci E, Sener EF, Özmen S, Gul MK, Tahtasakal R, Dal F

Objective: Pathways associated with glutamate receptors are known to play a role in the pathophysiology of attention-deficit hyperactivity disorder (ADHD). However, cyclin-dependent kinase 5 (CDK5), microtubule-associated protein-2 (MAP2), guanylate kinase-associated...
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The Importance of Low-frequency Alpha (8−10 Hz) Waves and Default Mode Network in Behavioral Inhibition

Kim YW, Kim S, Jin MJ, Im CH, Lee SH

Objective: Alpha wave of electroencephalography (EEG) is known to be related to behavioral inhibition. Both the alpha wave and default mode network (DMN) are predominantly activated during resting-state. To study...
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Treating Treatment-resistant Depression with Esketamine Nasal Spray When All Therapeutic Options Have Been Exhausted: Clinical Experience from a Spanish Cohort of Expanded Use

Vendrell-Serres J, Soto-Angona , Rodríguez-Urrutia A, Inzoli B, González AL, Ramos-Quiroga JA

  • KMID: 2553621
  • Clin Psychopharmacol Neurosci.
  • 2024 Feb;22(1):159-168.
  • doi: 10.9758/cpn.23.1097
Objective: Treatment Resistant Depression (TRD) is commonly defined as the lack of response to two or more antidepressants with different mechanisms of action. Up to 30% of patients diagnosed with...
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Thiol-disulphide Homeostasis in Patients with Schizophrenia: The Potential Biomarkers of Oxidative Stress in Acute Exacerbation of Schizophrenia

Korkmaz , Kaymak SU, Neşelioğlu S, Erel

  • KMID: 2553619
  • Clin Psychopharmacol Neurosci.
  • 2024 Feb;22(1):139-150.
  • doi: 10.9758/cpn.23.1084
Objective: Recent evidence suggests that oxidative stress contributes to the pathophysiology of schizophrenia. This study aimed to compare thiol-disulphide homeostasis in acute and stable phases of schizophrenia for the first...
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A Deep Learning Driven Simulation Analysis of the Emotional Profiles of Depression Based on Facial Expression Dynamics

Lee T, Baek S, Lee J, Chung ES, Yun K, Kim TS, Oh J

Objective: Diagnosis and assessment of depression rely on scoring systems based on questionnaires, either self-reported by patients or administered by clinicians, and observation of patient facial expressions during the interviews...
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Hyperarousal-state of Insomnia Disorder in Wake-resting State Quantitative Electroencephalography

Jang G, Jung HW, Kim J, Kim H, Shin J, Kim CH, Kim DH, Lee SK, Roh D

Objective: Insomnia is associated with elevated high-frequency electroencephalogram power in the waking state. Although affective symptoms (e.g., depression and anxiety) are commonly comorbid with insomnia, few reports distinguished objective sleep...
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Effects of Social Defeat Stress on Microtubule Regulating Proteins and Tubulin Polymerization

Le TH, Oh JM, Rami FZ, Li L, Chun SK, Chung YC

  • KMID: 2553618
  • Clin Psychopharmacol Neurosci.
  • 2024 Feb;22(1):129-138.
  • doi: 10.9758/cpn.23.1077
Objective: Microtubule (MT) stability in neurons is vital for brain development; instability is associated with neuropsychiatric disorders. The present study examined the effects of social defeat stress (SDS) on MT-regulating...
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The Relationship between Depression Severity and Prefrontal Hemodynamic Changes in Adolescents with Major Depression Disorder: A Functional Near-infrared Spectroscopy Study

Shin JE, Lee YS, Park SY, Jeong MY, Choi JK, Cha JH, Lee YJ

  • KMID: 2553617
  • Clin Psychopharmacol Neurosci.
  • 2024 Feb;22(1):118-128.
  • doi: 10.9758/cpn.23.1073
Objective: Numerous studies have identified hemodynamic changes in adults with major depressive disorder (MDD) by using functional near-infrared spectroscopy (fNIRS). However, studies on adolescents with MDD are limited. As adolescence...
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Is Every Thyroid Antibody a Bad Sign?: The Complex Relationship of Antithyroid Antibodies and Obsessive-compulsive Symptoms

Caykoylu A, Ugurlu M, Sahin EK, Akan S, Ugurlu GK, Erdogan EC, Alkan EU

Objective: Several immunological factors are emphasized in the etiology of autoimmune thyroid diseases and obsessivecompulsive disorder. Obsessive-compulsive symptoms (OCS) are commonly seen in patients with autoimmune thyroid diseases. This study...
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The Association between Default-mode Network Functional Connectivity and Childhood Trauma on the Symptom Load in Male Adults with Methamphetamine Use Disorder

Wei SY, Tsai TH, Tsai TY, Chen PS, Tseng HH, Yang YK, Zhai T, Yang Y, Wang TY

  • KMID: 2553616
  • Clin Psychopharmacol Neurosci.
  • 2024 Feb;22(1):105-117.
  • doi: 10.9758/cpn.23.1079
Objective: The relationship between adverse childhood experiences and methamphetamine use disorder (MUD) has been shown in previous studies; nevertheless, the underlying neural mechanisms remain elusive. Childhood trauma is associated with...
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