- Comment on “Prognostic Role of Claudin-1 Immunohistochemistry in Malignant Solid Tumors: A Meta-Analysisâ€
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Wang B, Huang Y
- KMID: 2465443
- J Pathol Transl Med.
- 2019 Nov;53(6):411-411.
- doi: 10.4132/jptm.2019.09.26
No abstract available. -
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- Expression of Claudin-1 and -7 in Clear Cell Renal Cell Carcinoma and Its Clinical Significance
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Shin HI, Kim BH, Chang HS, Kim CI, Jung HR, Park CH
- KMID: 2315518
- Korean J Urol.
- 2011 May;52(5):317-322.
PURPOSE: We investigated the correlations between the expression of claudin-1 and claudin-7 in clear cell renal cell carcinoma (clear cell RCC) and clinical parameters. MATERIALS AND METHODS: The subjects of this... -
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- Expressions of Tight Junction Protein Claudin-1 and Claudin-7 in Squamous Cell Carcinoma of the Uterine Cervix
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Lee JW, Lee YY, Yang SY, Lee SJ, Kim CJ, Kim BG, Park CS, Lee JH, Bae DS
- KMID: 2244927
- Korean J Gynecol Oncol Colposc.
- 2004 Mar;15(1):41-47.
OJECTIVE : Claudins have been shown to be up-regulated in various cancers and have been suggested as possible biomarkers and targets for cancer therapy. The aims of this study were... -
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- Increased expressions of claudin-1 and claudin-7 in cervical squamous intraepithelial neoplasias and invasive squamous cell carcinomas
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Song ES, Lee BI, Kim JM, Lee KY, An KS, Sung SM, Kwon HJ, Park JH, Han JY, Choi SJ
- KMID: 2141699
- Korean J Obstet Gynecol.
- 2006 May;49(5):1065-1072.
OBJECTIVE: The change of claudin expressions, integral transmembrane proteins for tight junction, might be related to progression of cervical premalignancy or malignancy. The aim of this study was to verify... -
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- Correlation between Claudins Expression and Prognostic Factors in Prostate Cancer
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Seo KW, Kwon YK, Kim BH, Kim CI, Chang HS, Choe MS, Park CH
- KMID: 2314836
- Korean J Urol.
- 2010 Apr;51(4):239-244.
PURPOSE: The purpose of this study was to evaluate the correlation between the expression of claudins and prognostic factors in patients with prostate cancer. MATERIALS AND METHODS: The subjects of... -
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- Expression of Claudin-1 and -4 in Benign Lesions and Invasive Ductal Carcinomas of the Breast
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Choi HJ, Jung JH, Yoo J, Kang SJ, Lee KY
- KMID: 1521637
- Korean J Pathol.
- 2007 Aug;41(4):232-237.
BACKGROUND: The claudins are a family of transmembrane proteins associated with tight junctions and they are critical for maintaining cell-to-cell adhesion in sheets of epithelial cells. However, their role in... -
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- Expression of claudin-1, claudin-4 and zonula occludens-1 in cervical intraepithelial neoplasia and invasive squamous cell carcinoma
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Lee SK, Rho HK, Park TY, Kang KH, Cho TI, Lee TJ
- KMID: 2077793
- Korean J Obstet Gynecol.
- 2007 Oct;50(10):1378-1385.
OBJECTIVE: Cell to cell and cell to extracellular matrix interaction are crucial in tumor development and progression. Tight junction proteins such as claudins and zonula occludens-1 (ZO-1) play an important... -
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- Prognostic Role of Claudin-1 Immunohistochemistry in Malignant Solid Tumors: A Meta-Analysis
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Pyo JS, Kim NY, Cho WJ
- KMID: 2449340
- J Pathol Transl Med.
- 2019 May;53(3):173-179.
- doi: 10.4132/jptm.2019.02.03
BACKGROUND: Although the correlation between low claudin-1 expression and worse prognosis has been reported, details on the prognostic implications of claudin-1 expression in various malignant tumors remain unclear. The present... -
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- Significance of the Decreased Expressions of Claudin-1 and ZO-1 Protein as Prognostic Factors in Breast Cancer
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Kim MJ, Cha SJ, Park SI, Park SJ, Chang IT, Kim BG, Choi YS, Lee TJ
- KMID: 2040612
- J Korean Surg Soc.
- 2007 Jun;72(6):453-459.
PURPOSE: Tight junction proteins are either over-expressed or suppressed in some cancers. These suppressions of claudin-1 and ZO-1 protein are known to have a significant relationship with the progression of... -
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- Prognostic Significance of Claudin 4 in Completely Resected Adenocarcinoma of the Lung
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Chae MC, Park CK, Keum DY, Hwang I, Kwon KY, Jang BC
- KMID: 2288790
- Korean J Thorac Cardiovasc Surg.
- 2014 Jun;47(3):262-268.
BACKGROUND: The development of diagnostic techniques and an awareness of health examinations can bring about an early diagnosis of lung cancer. However, appropriate postoperative management and adjuvant chemotherapy remain under... -
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- Expression of Claudin-1 in the Fetal Skin during the Developmental Stage
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Kim HK, Ko YS, Joh OJ, Lee JS, Song KY
- KMID: 1771543
- Korean J Dermatol.
- 2008 Aug;46(8):1048-1055.
BACKGROUND: Claudins are integral membrane proteins at tight junctions of simple epithelium and have an important role in cell-cell adhesion and barrier function. Their altered expression modifies the biological function... -
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- Indol-3-Carbinol Regulated Tight Junction Permeability and Associated-Protein Level and Suppressed Cell Invasion in Human Colon Cancer Cell Line, HT-29
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Kim SO, Choi YH, Choe WK
- KMID: 2261191
- Korean J Nutr.
- 2008 Jan;41(1):13-21.
To determine whether indol-3-carbinol (I3C, C9H9NO), an autolysis product of a glucosinolate and a glucobrassicin in vegetables, regulated tight junction proteins (TJ) and suppressed cell invasion in colon cancer cells,this... -
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- Acute Modulations in Stratum Corneum Permeability Barrier Function Affect Claudin Expression and Epidermal Tight Junction Function via Changes of Epidermal Calcium Gradient
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Baek JH, Lee SE, Choi KJ, Choi EH, Lee SH
- KMID: 1503920
- Yonsei Med J.
- 2013 Mar;54(2):523-528.
- doi: 10.3349/ymj.2013.54.2.523
Tight junction (TJ) is recognized as a second barrier of the skin. Altered expression of TJ proteins in various skin diseases characterized by the abnormal permeability barrier such as psoriasis... -
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- Comparison of Tight Junction Protein-Related Gene mRNA Expression Levels between Male and Female Gastroesophageal Reflux Disease Patients
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Kim JJ, Kim N, Park JH, Kim YS, Lee SM, Lee DH, Jung HC
- KMID: 2417307
- Gut Liver.
- 2018 Jul;12(4):411-419.
- doi: 10.5009/gnl17419
BACKGROUND/AIMS: Male predominance has been observed in the erosive reflux disease (ERD), but reverse finding in nonerosive reflux disease (NERD). This suggests sex-specific medicine approach is needed but its mechanism... -
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- Additive Effects of Rebamipide Plus Proton Pump Inhibitors on the Expression of Tight Junction Proteins in a Rat Model of Gastro-Esophageal Reflux Disease
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Gweon TG, Park JH, Kim BW, Choi YK, Kim JS, Park SM, Kim CW, Kim HG, Chung JW, Incheon and Western Kyonggi Gastrointestinal Study Group
- KMID: 2404716
- Gut Liver.
- 2018 Jan;12(1):46-50.
- doi: 10.5009/gnl17078
BACKGROUND/AIMS: The aim of this study was to investigate the effects of rebamipide on tight junction proteins in the esophageal mucosa in a rat model of gastroesophageal reflux disease (GERD). METHODS:... -
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- Particulate Matter 2.5 Causes Deficiency in Barrier Integrity in Human Nasal Epithelial Cells
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Xian M, Ma S, Wang K, Lou H, Wang Y, Zhang L, Wang C, Akdis CA
- KMID: 2462572
- Allergy Asthma Immunol Res.
- 2020 Jan;12(1):56-71.
- doi: 10.4168/aair.2020.12.1.56
PURPOSE: The effect of air pollution-related particulate matter (PM) on epithelial barrier function and tight junction (TJ) expression in human nasal mucosa has not been studied to date. This study... -
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- NFATC3–PLA2G15 Fusion Transcript Identified by RNA Sequencing Promotes Tumor Invasion and Proliferation in Colorectal Cancer Cell Lines
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Jang JE, Kim HP, Han SW, Jang H, Lee SH, Song SH, Bang D, Kim TY
- KMID: 2437629
- Cancer Res Treat.
- 2019 Jan;51(1):391-401.
- doi: 10.4143/crt.2018.103
PURPOSE: This study was designed to identify novel fusion transcripts (FTs) and their functional significance in colorectal cancer (CRC) lines. MATERIALS AND METHODS: We performed paired-end RNA sequencing of 28 CRC... -
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- High-fat Diet Accelerates Intestinal Tumorigenesis Through Disrupting Intestinal Cell Membrane Integrity
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Park MY, Kim MY, Seo YR, Kim JS, Sung MK
- KMID: 2353809
- J Cancer Prev.
- 2016 Jun;21(2):95-103.
- doi: 10.15430/JCP.2016.21.2.95
BACKGROUND: Excess energy supply induces chronic low-grade inflammation in association with oxidative stress in various tissues including intestinal epithelium. The objective of this study was to investigate the effect of... -
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