- Clinical Application Value of Lactobacillus Plantarum PS128 in Patients with Anxiety Disorders
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Meng X, Gao Y, Qi H, Ding Y, Sun Y
- KMID: 2532822
- Clin Psychopharmacol Neurosci.
- 2022 Aug;20(3):560-566.
- doi: 10.9758/cpn.2022.20.3.560
Objective: PS128 is a novel psycho biotic strain, it has been reported to play an important role in neuropsychiatric disorders. This study investigated the clinical effect of PS128 supplementation on... -
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- Selective serotonin reuptake inhibitor escitalopram inhibits 5-HT₃ receptor currents in NCB-20 cells
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Park YS, Sung KW
- KMID: 2461044
- Korean J Physiol Pharmacol.
- 2019 Nov;23(6):509-517.
- doi: 10.4196/kjpp.2019.23.6.509
Escitalopram is one of selective serotonin reuptake inhibitor antidepressants. As an S-enantiomer of citalopram, it shows better therapeutic outcome in depression and anxiety disorder treatment because it has higher selectivity... -
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- Pharmacological and Neuromodulatory Treatments for Panic Disorder: Clinical Trials from 2010 to 2018
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Zugliani M, Cabo MC, Nardi AE, Perna G, Freire RC
- KMID: 2438158
- Psychiatry Investig.
- 2019 Jan;16(1):50-58.
- doi: 10.30773/pi.2018.12.21.1
OBJECTIVE: Treatment for panic disorder (PD) have evolved, although there is still a strong unmet need for more effective and tolerable options. The present study summarizes and discusses recent evidence... -
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- Differences in Therapeutic Responses and Factors Affecting Post-Stroke Depression at a Later Stage According to Baseline Depression
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Lee EJ, Kim JS, Chang DI, Park JH, Ahn SH, Cha JK, Heo JH, Sohn SI, Lee BC, Kim DE, Kim HY, Kim S, Kwon DY, Kim J, Seo WK, Lee J, Park SW, Koh SH, Kim JY, Choi-Kwon , Kim MS, Lee JS, the EMOTION Investigators
- KMID: 2424429
- J Stroke.
- 2018 May;20(2):258-267.
- doi: 10.5853/jos.2017.02712
BACKGROUND AND PURPOSE: The pathophysiology of post-stroke depression (PSD) is complex and may differ according to an individual’s mood immediately after stroke. Here, we compared the therapeutic response and clinical... -
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- Serum N-Desmethylcitalopram Concentrations are Associated with the Clinical Response to Citalopram of Patients with Major Depression
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Ozbey G, Yucel B, Bodur NE, Taycan SE, Arslan T, Cerit N, Yuksel N, Guzey IC, Uluoglu C
- KMID: 2429161
- Psychiatry Investig.
- 2018 Mar;15(3):313-319.
- doi: 10.30773/pi.2017.05.22
OBJECTIVE: Citalopram (CITA) is a widely used and well-tolerated selective serotonin reuptake inhibitor. The aim of the study was to evaluate the possible influences of serum concentrations of CITA and... -
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- Paroxetine versus Venlafaxine and Escitalopram in Korean Patients with Major Depressive Disorder: A Randomized, Rater-blinded, Six-week Study
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Woo YS, McIntyre R, Kim JB, Lee MS, Kim JM, Yim HW, Jun TY
- KMID: 2396310
- Clin Psychopharmacol Neurosci.
- 2017 Nov;15(4):391-401.
- doi: 10.9758/cpn.2017.15.4.391
OBJECTIVE: The purpose of this study was to compare the efficacy and safety of escitalopram, paroxetine and venlafaxine in Korean patients with major depressive disorder (MDD). METHODS: A total of 449... -
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- Comparing the Effects of Bupropion and Escitalopram on Excessive Internet Game Play in Patients with Major Depressive Disorder
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Nam B, Bae S, Kim SM, Hong JS, Han DH
- KMID: 2396307
- Clin Psychopharmacol Neurosci.
- 2017 Nov;15(4):361-368.
- doi: 10.9758/cpn.2017.15.4.361
OBJECTIVE: Several studies have suggested the efficacy of bupropion and escitalopram on reducing the excessive internet game play. We hypothesized that both bupropion and escitalopram would be effective on reducing... -
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- Escitalopram, a selective serotonin reuptake inhibitor, inhibits voltage-dependent Kâ» channels in coronary arterial smooth muscle cells
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Kim HS, Li H, Kim HW, Shin SE, Seo MS, An JR, Ha KS, Han ET, Hong SH, Choi IW, Choi G, Lee DS, Park WS
- KMID: 2384455
- Korean J Physiol Pharmacol.
- 2017 Jul;21(4):415-421.
- doi: 10.4196/kjpp.2017.21.4.415
We investigated the inhibitory effect of escitalopram, a selective serotonin reuptake inhibitor (SSRI), on voltage-dependent K⺠(Kv) channels in freshly separated from rabbit coronary arterial smooth muscle cells. The application... -
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- Effects of Escitalopram on Anxiety in Patients with Acute Coronary Syndrome: A Randomized Controlled Trial
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Kang HJ, Bae KY, Kim SW, Shin IS, Hong YJ, Ahn Y, Jeong MH, Yoon JS, Kim JM
- KMID: 2378480
- Clin Psychopharmacol Neurosci.
- 2017 May;15(2):126-131.
- doi: 10.9758/cpn.2017.15.2.126
OBJECTIVE: There are no evidence-based practices for treating anxiety in patients with acute coronary syndrome (ACS). Thus, we investigated the effects of escitalopram on anxiety in this population. METHODS: We enrolled... -
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- Association of citalopram with congenital anomalies: A meta-analysis
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Kang HH, Ahn KH, Hong SC, Kwon BY, Lee EH, Lee JS, Oh MJ, Kim HJ
- KMID: 2372798
- Obstet Gynecol Sci.
- 2017 Mar;60(2):145-153.
- doi: 10.5468/ogs.2017.60.2.145
OBJECTIVE: The antenatal use of citalopram, a widely prescribed selective serotonin reuptake inhibitor, has been suspected to be associated with congenital, particularly cardiac, anomalies. This study aimed to prove the... -
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- Times to Discontinue Antidepressants Over 6 Months in Patients with Major Depressive Disorder
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Jung WY, Jang SH, Kim SG, Jae YM, Kong BG, Kim HC, Choe BM, Kim JG, Kim CR
- KMID: 2344743
- Psychiatry Investig.
- 2016 Jul;13(4):440-446.
- doi: 10.4306/pi.2016.13.4.440
OBJECTIVE: The aim of the present study was to investigate differences in discontinuation time among antidepressants and total antidepressant discontinuation rate of patients with depression over a 6 month period... -
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- Early Improvement in One Week Predicts the Treatment Response to Escitalopram in Patients with Social Anxiety Disorder: A Preliminary Study
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Oh KS, Shin E, Ha J, Shin D, Shin Y, Lim SW
- KMID: 2170984
- Clin Psychopharmacol Neurosci.
- 2016 May;14(2):161-167.
- doi: 10.9758/cpn.2016.14.2.161
OBJECTIVE: Social anxiety disorder (SAD) shows relatively delayed responses to pharmacotherapy when compared to other anxiety disorders. Therefore, more effective early therapeutic decisions can be made if the therapeutic response... -
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- Design and Methodology for the Korean Observational and Escitalopram Treatment Studies of Depression in Acute Coronary Syndrome: K-DEPACS and EsDEPACS
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Kim JM, Bae KY, Kang HJ, Kim SW, Shin IS, Hong YJ, Kim JH, Shin HY, Ahn Y, Kim JK, Jeong MH, Yoon JS
- KMID: 2316336
- Psychiatry Investig.
- 2014 Jan;11(1):89-94.
Depression is common after acute coronary syndrome (ACS), adversely affecting cardiac course and prognosis. There have been only a few evidence-based treatment options for depression in ACS. Accordingly, we planned... -
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- Long-Term Tolerability of Escitalopram in Korean Adolescents
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Goo AJ, Won EK, Lee C, Lee JI, Jung HY, Kim Y
- KMID: 2291617
- J Korean Acad Child Adolesc Psychiatry.
- 2013 Dec;24(4):207-212.
OBJECTIVES: We investigated the long-term tolerability of escitalopram in Korean adolescents. METHODS: The subjects were 37 adolescents, who had been diagnosed with depressive disorder in accordance to DSM-IV. Clinical effectiveness was... -
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- CYP2D6 P34S Polymorphism and Outcomes of Escitalopram Treatment in Koreans with Major Depression
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Han KM, Chang HS, Choi IK, Ham BJ, Lee MS
- KMID: 2316302
- Psychiatry Investig.
- 2013 Sep;10(3):286-293.
OBJECTIVE: Cytochrome P450 (CYP) enzymatic activity, which is influenced by CYP genetic polymorphism, is known to affect the inter-individual variation in the efficacy and tolerability of antidepressants in major depressive... -
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- A Case of Serotonin Syndrome Due to Amantadine and Escitalopram in End-Stage Renal Disease
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Choi JS, Lee EK
- KMID: 2263510
- Korean J Med.
- 2012 Jul;83(1):122-126.
Serotonin syndrome is a potentially life-threatening adverse drug reaction caused by excessive serotonergic activity in the nervous system. It is characterized by a triad of mental status changes, autonomic hyperactivity,... -
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- Interaction of Morphine and Selective Serotonin Receptor Inhibitors in Rats Experiencing Inflammatory Pain
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Lee BS, Jun IG, Kim SH, Park JY
- KMID: 2157905
- J Korean Med Sci.
- 2012 Apr;27(4):430-436.
- doi: 10.3346/jkms.2012.27.4.430
Citalopram and paroxetine are selective serotonin reuptake inhibitors and also have antinociceptive effects. We investigated the antiallodynic and antihyperalgesic effects of intrathecally administered morphine, citalopram, paroxetine, and combinations thereof, in... -
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- Long-term Escitalopram Treatment in Korean Patients with Panic Disorder: A Prospective, Naturalistic, Open-label, Multicenter Trial
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Choi KW, Woo JM, Kim YR, Lee SH, Lee SY, Kim EJ, Chung SK, Kang EH, Lee JH, Yu BH
- KMID: 2134673
- Clin Psychopharmacol Neurosci.
- 2012 Apr;10(1):44-48.
OBJECTIVE: Panic disorder is characterized by recurrent panic attacks, persistent concerns about additional attacks, and worry about the implications of the attack or significant changes in behavior related to the... -
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- Developmental Switch of the Serotonergic Role in the Induction of Synaptic Long-term Potentiation in the Rat Visual Cortex
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Park SW, Jang HJ, Cho KH, Kim MJ, Yoon SH, Rhie DJ
- KMID: 2285442
- Korean J Physiol Pharmacol.
- 2012 Feb;16(1):65-70.
- doi: 10.4196/kjpp.2012.16.1.65
Synaptic long-term potentiation (LTP) and long-term depression (LTD) have been studied as mechanisms of ocular dominance plasticity in the rat visual cortex. Serotonin (5-hydroxytryptamine, 5-HT) inhibits the induction of LTP... -
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- Predictors of Clinical Response to Escitalopram in Obsessive-Compulsive Disorder
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Yun JY, Byun MS, Shim G, Park HY, Jang JH, Hwang JY, Kim SN, Kwon JS
- KMID: 2287485
- Korean J Psychopharmacol.
- 2011 Oct;22(4):214-222.
OBJECTIVE: In this study, we aimed to investigate the predictors of clinical response to escitalopram (ESC) in obsessive-compulsive disorder (OCD) from the baseline clinical characteristics. In addition, we aimed to... -
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