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Persistent Malfunction of Glymphatic and Meningeal Lymphatic Drainage in a Mouse Model of Subarachnoid Hemorrhage

Pu T, Zou W, Feng W, Zhang Y, Wang L, Wang H, Xiao M

Subarachnoid hemorrhage (SAH) is a devastating cerebrovascular event that often is followed by permanent brain impairments. It is necessary to explore the pathogenesis of secondary pathological damages in order to...
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In Vivo Spinal Distribution of Cy5.5 Fluorescent Dye after Injection via the Lateral Ventricle and Cisterna Magna in Rat Model

Lee KH, Nam H, Won JS, Hwang JY, Jang HW, Lee SH, Joo KM

OBJECTIVE: The purpose of this study was to find an optimal delivery route for clinical trials of intrathecal cell therapy for spinal cord injury in preclinical stage. METHODS: We compared in...
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A Case of Smith-Magenis Syndrome with Multiple Organ Malformations

Kim SE, Kim G, Suh JS, Lee J

Smith-Magenis syndrome (SMS) is a genetic disease caused by microdeletion of p11.2 in chromosome 17. SMS patients have characteristic facial features and accompanying congenital malformations involving the brain, cardiovascular system,...
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Atypical Neonatal Marfan Syndrome with p.Glu1073Lys Mutation of FBN1: the First Case in Korea

Heo JS, Song JY, Choi EY, Kim EH, Kim JH, Park SE, Jeon JH

Neonatal Marfan syndrome (nMFS) is considered to be on the most severe end of the spectrum of type I fibrillinopathies. The common features of nMFS include ascending aortic dilatation, severe...
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Surgical Outcome of Adult Idiopathic Chiari Malformation Type 1

Yuh WT, Kim CH, Chung CK, Kim HJ, Jahng TA, Park SB

OBJECTIVE: The pathophysiology of idiopathic Chiari malformation (CM) type 1 is disturbance of free cerebrospinal fluid (CSF) flow and restoration of normal CSF flow is the mainstay of treatment. Additional...
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An unusual de novo duplication 10p/deletion 10q syndrome: The first case in Korea

Lee BY, Park JY, Lee YW, Oh AR, Lee SY, Choi EY, Kim MY, Ryu HM, Park SY

We herein report an analysis of a female baby with a de novo dup(10p)/del(10q) chromosomal aberration. A prenatal cytogenetic analysis was performed owing to abnormal ultrasound findings including a choroid...
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Stereological and Morphometric Analysis of MRI Chiari Malformation Type-1

Alkoc OA, Songur A, Eser O, Toktas M, Gonul Y, Esi E, Haktanir A

OBJECTIVE: In this study, we aimed to investigate the underlying ethiological factors in chiari malformation (CM) type-I (CMI) via performing volumetric and morphometric length-angle measurements. METHODS: A total of 66 individuals...
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Survival of Patients with Trisomy 18 Based on the Treatment Policy at a Single Center in Korea

Nam SY, Ahn SY, Chun JY, Yoon SA, Park GY, Choi SY, Sung SI, Yoo HS, Chang YS, Park WS

PURPOSE: Although discussion about active treatment of trisomy 18 is increasing, there are no previous articles regarding this subject in Korea. In order to provide objective data about the clinical...
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Effects of Palonosetron, a 5-HT3 Receptor Antagonist, on Mechanical Allodynia in a Rat Model of Postoperative Pain

Jung KT, Yoon MH, Lee HY, Yu BY, Kim DK, Lim KJ

BACKGROUND: 5-hydroxytryptamine 3 (5-HT3) receptors have been known to be associated with the modulation of nociceptive transmission. However, it is uncertain whether 5-HT3 plays a role in the antinociceptive or...
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Manic Episode Associated with Mega Cisterna Magna

Turan T, Besirli A, Asdemir A, Ozsoy S, Esel E

  • KMID: 2315920
  • Psychiatry Investig.
  • 2010 Dec;7(4):305-307.
Mega cisterna magna is a part of "Dandy-Walker Complex" and it is characterized by the enlargement of the cisterna magna, morphologically intact vermis and cerebellar hemispheres. We report a case...
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Comparison of fetal magnetic resonance imaging and ultrasonography for the diagnosis of fetal anomalies

Kim MJ, Kim HJ, Ji HY, Seo ES, Choi SJ, Roh CR, Oh SY, Kim JH

  • KMID: 2280774
  • Korean J Perinatol.
  • 2008 Sep;19(3):248-255.
PURPOSE: To compare the accuracy of fetal magnetic resonance imaging (MRI) and prenatal ultrasonography (USG) with postnatal diagnosis for the diagnosis of fetal anomalies. METHODS: Retrospective analysis of 41 fetuses who...
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Gene Transfer of Cu/ZnSOD to Cerebral Vessels Prevents Subarachnoid Hemorrhage-induced Cerebral Vasospasm

Yun MR, Kim DE, Heo HJ, Park JY, Lee JY, Bae SS, Kim CD

  • KMID: 2071615
  • Korean J Physiol Pharmacol.
  • 2005 Dec;9(6):327-332.
The preventive effects of gene transfer of human copper/zinc superoxide dismutase (Cu/ZnSOD) on the development of cerebral vasospasm after subarachnoid hemorrhage (SAH) were examined using a rat model of SAH....
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Factors Related with Intracranial Signs in Fetuses with Open Neural Tube Defect

Kim GJ, Lee ES, Kim DH, Lee SH, Park JD, Park MH

  • KMID: 2272726
  • Korean J Obstet Gynecol.
  • 2005 Nov;48(11):2541-2549.
OBJECTIVE: There are two types of spina bifida aperta: cystic type and flat type. Unruptured cystic sac of spina bifida may interfere free leakage of cerebrospinal fluid into amnionic fluid...
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Hemorrhage in the Cisterna Magna after Acupuncture

Jeon JS, Cho SM, Cho YJ, Hong SK

  • KMID: 2339818
  • J Korean Neurosurg Soc.
  • 2004 Nov;36(5):412-414.
Acupuncture is one of the most popular complimentary therapies these days not only in Asia, but also in USA and Europe. Acupuncture is generally regarded as a safe procedure in...
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A Case of Congenital Cytomegalovirus Infection with Severe Hydrocephalus in Prenatal Ultrasonography

Cho GJ, Oh MJ, Chung JW, Chung OS, Lee JK, Hur JY, Saw HS, Park YK, Lee JH

  • KMID: 2272448
  • Korean J Obstet Gynecol.
  • 2004 Nov;47(11):2224-2228.
Cytomegalovirus (CMV) infection is one of the most common viral infections in human and it is known to cause primary and recurrent infections. CMV is spread to the fetus in...
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Three Cases of Spina Bifida by Antenatal Ultrasonogram

Kim MJ, Kim MK, Park HJ, Seol HJ, Shin JH, Kang MJ, An HS

  • KMID: 2272113
  • Korean J Obstet Gynecol.
  • 2003 Jul;46(7):1445-1452.
The prenatal diagnosis of spina bifida includes the combined use of maternal serum alpha-fetoprotein (MSAFP) screening and fetal sonography. On ultrasonogram, spina bifida is characterizd by visualization of the spinal...
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Vasomotor Reactivity of the Spasm Model by the Polystyrene Latex Bead

Song KJ, Kang SD

  • KMID: 2339675
  • J Korean Neurosurg Soc.
  • 2002 Apr;31(4):352-356.
OBJECTIVE: It has been reported that the presence of a pharmacologically inactive foreign substance, polystyrene latex bead, in subarachnoid space activates a non-specific immunological response and elicits arterial narrowing. In...
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Involvement of Vascular NAD(P)H Oxidase-derived Superoxide in Cerebral Vasospasm after Subarachnoid Hemorrhage in Rats

Kim DE, Kim CD

  • KMID: 1614853
  • Korean J Physiol Pharmacol.
  • 2002 Feb;6(1):15-20.
The role of vascular NAD(P)H oxidase in subarachnoid hemorrhage (SAH)-induced vasospasm in the basilar artery was examined in a rat model. Arterial vasospasm characterized by increased wall thickness and decreased...
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The protective effect of nitirc oxide synthase inhibitor on hearing loss induced by TNF-alpha and IL-1beta injection into CSF in guinea pigs

Rhee CK, Jeon SJ, Jung SW, Lee CH, Oh CH

  • KMID: 2275739
  • Korean J Otolaryngol-Head Neck Surg.
  • 2001 Aug;44(8):794-799.
BACKGROUND AND OBJECTIVES: One of the most serious complications of bacterial meningitis, particularly in childhood, is sensorineural hearing loss; yet the mechanisms of this hearing loss are not clearly understood....
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Clinical Usefulness of Magnetic Resonance Cisternography in Patients Having Hemifacial Spasm

Lee MS, Kim MS, Hong IS, Whang K, Han YP

To evaluate the usefulness of MR cisternography fourteen patients that had hemifacial spasm and 20 control patients underwent MR cisternography. All the patients with hemifacial spasm had a confirmed vascular...
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