- MHY2251, a New SIRT1 Inhibitor, Induces Apoptosis via JNK/p53 Pathway in HCT116 Human Colorectal Cancer Cells
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Kang YJ, Kwon YH, Jang JY, Lee JH, Lee S, Park Y, Moon HR, Chung HY, Kim ND
- KMID: 2537583
- Biomol Ther.
- 2023 Jan;31(1):73-81.
- doi: 10.4062/biomolther.2022.044
Sirtuins (SIRTs) belong to the nicotinamide adenine dinucleotide (NAD+)-dependent class III histone deacetylase family. They are key regulators of cellular and physiological processes, such as cell survival, senescence, differentiation, DNA... -
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- The efficacy and safety of Dendropanax morbifera leaf extract on the metabolic syndrome: a 12-week, placebo controlled, double blind, and randomized controlled trial
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Jun JE, Hwang YC, Ahn KJ, Chung HY, Choung SY, Jeong IK
- KMID: 2525513
- Nutr Res Pract.
- 2022 Feb;16(1):60-73.
- doi: 10.4162/nrp.2022.16.1.60
BACKGROUND/OBJECTIVES: The extract from Dendropanax morbifera exhibited diverse therapeutic potentials. We aimed to evaluate the efficacy and safety of D. morbifera leaf extract for improving metabolic parameters in human. SUBJECTS/METHODS: A... -
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- Classification, diagnosis, and treatment of vascular malformations
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Lee JS, Chung HY
- KMID: 2520192
- J Korean Med Assoc.
- 2021 Sep;64(9):614-621.
- doi: 10.5124/jkma.2021.64.9.614
Background: In the 1980s, vascular anomalies were divided into two major subgroups—vascular tumors and vascular malformations—based on the functional framework. This concept has been fundamental to the management of vascular... -
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- Effects of Advanced Glycation End Products on Differentiation and Function of Osteoblasts and Osteoclasts
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Park SY, Choi KH, Jun JE, Chung HY
- KMID: 2520365
- J Korean Med Sci.
- 2021 Sep;36(37):e239.
- doi: 10.3346/jkms.2021.36.e239
Background: Risk of fragility fractures increases in patients with diabetes mellitus, independent of bone mineral density. In the present study, the effects of advanced glycation end products (AGEs) on differentiation... -
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- Age-Dependent Sensitivity to the Neurotoxic Environmental Metabolite, 1,2-Diacetylbenzene
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Hoang NMH, Kim S, Nguyen HD, Kim M, Kim J, Kim BC, Park D, Lee S, Yu BP, Chung HY, Kim MS
- KMID: 2517158
- Biomol Ther.
- 2021 Jul;29(4):399-409.
- doi: 10.4062/biomolther.2020.208
1,2-Diacetylbenzene (DAB) is a metabolite of 1,2-diethylbenzene, which is commonly used in the manufacture of plastics and gasoline. We examined the neurotoxic effects of DAB in young and old rats,... -
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- Clinical assessment and management of auricular arteriovenous malformation: retrospective study
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Kim DG, Cho HG, Ryu JY, Lee JS, Lee SJ, Lee JM, Lee SY, Huh S, Kim JY, Chung HY
- KMID: 2517008
- Arch Craniofac Surg.
- 2021 Jun;22(3):141-147.
- doi: 10.7181/acfs.2021.00192
Background: Arteriovenous malformation (AVM) which is a high-blood-flow lesion with connections between arteries and veins without an intervening capillary bed, is difficult to manage. The ear is the second most... -
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- Signaling Role of Adipocyte Leptin in Prostate Cell Proliferation Induced by Trichomonas vaginalis
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Kim JH, Han IH, Shin SJ, Park SY, Chung HY, Ryu JS
- KMID: 2517054
- Korean J Parasitol.
- 2021 Jun;59(3):235-249.
- doi: 10.3347/kjp.2021.59.3.235
Leptin is a type of adipokine mainly produced by adipocytes and reported to be overproduced in prostate cancer. However, it is not known whether it stimulates the proliferation of prostate... -
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- Usefulness of meshed SurgiMend in direct-to-implant breast reconstruction
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Eo PS, Lee JS, Lee JW, Choi KY, Chung HY, Cho BC, Lee J, Park HY, Yang JD
- KMID: 2515402
- Arch Aesthetic Plast Surg.
- 2021 Apr;27(2):69-75.
- doi: 10.14730/aaps.2020.02383
Background The use of acellular dermal matrix in implant-based breast reconstruction immediately after mastectomy has attracted attention in recent years because it yields good outcomes. Herein, we analyzed the usefulness... -
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- Effectiveness and Safety of Two Different Formulations of Oral Propranolol Treatment for 375 Cases of Infantile Hemangioma: A Korean Single-center Experience
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Lee HJ, Ha G, Chung HY, Lee JM, Lee SY, Huh S, Kim JY, Lee SJ
- KMID: 2514430
- Korean J Dermatol.
- 2021 Mar;59(3):196-205.
Background: Oral propranolol has recently been introduced as a successful treatment for infantile hemangioma (IH). Though, there are limited reports on this treatment including large number of Korean patients with IH... -
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- Mechanism of Lipid Accumulation through PAR2 Signaling in Diabetic Male Mice
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Kim DH, Kim YR, Bang E, Ha S, Noh SG, Kim BM, Jeong SH, Jung HJ, Lee JY, Chung HY
- KMID: 2513300
- Endocrinol Metab.
- 2021 Feb;36(1):171-184.
- doi: 10.3803/EnM.2020.850
Background: Protease-activated protein-2 (PAR2) has been reported to regulate hepatic insulin resistance condition in type 2 diabetes mice. However, the mechanism of lipid metabolism through PAR2 in obesity mice have... -
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- The role of peer-reviewed journals in esthetic surgery
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Dhong ES, Chung HY
- KMID: 2512292
- Arch Aesthetic Plast Surg.
- 2021 Jan;27(1):1-2.
- doi: 10.14730/aaps.2020.02418
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- Successful Microsurgical Replantation of Scalp Amputation Using Medicinal and Chemical Leech Therapy: A Case Report
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Lee JH, Kim DG, Choi KY, Chung HY, Lee JS
- KMID: 2508948
- Arch Hand Microsurg.
- 2020 Dec;25(4):320-325.
- doi: 10.12790/ahm.20.0058
Scalp amputation is a very rare occurrence worldwide. In particular, replantation failure may occur from venous congestion, which represents a major complication of replantation. Accordingly, this study reports on a... -
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- Open-Door Laminoplasty Using Lateral Mass Anchoring Screws and Nonabsorbable Sutures in Patients with Multilevel Cervical Myelopathy
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Cha JR, Kim HW, Yang DG, Chung HY, Hwang IY
- KMID: 2508778
- Clin Orthop Surg.
- 2020 Dec;12(4):477-484.
- doi: 10.4055/cios20013
Background: The purpose of this study was to evaluate the clinical usefulness of open-door laminoplasty using lateral mass anchoring screws and nonabsorbable sutures (ODLLM) for multilevel cervical myelopathy. Methods: We retrospectively... -
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- Novel SIRT Inhibitor, MHY2256, Induces Cell Cycle Arrest, Apoptosis, and Autophagic Cell Death in HCT116 Human Colorectal Cancer Cells
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Kim MJ, Kang YJ, Sung B, Jang JY, Ahn YR, Oh HJ, Choi H, Choi I, Im E, Moon HR, Chung HY, Kim ND
- KMID: 2508211
- Biomol Ther.
- 2020 Nov;28(6):561-568.
- doi: 10.4062/biomolther.2020.153
We examined the anticancer effects of a novel sirtuin inhibitor, MHY2256, on HCT116 human colorectal cancer cells to investigate its underlying molecular mechanisms. MHY2256 significantly suppressed the activity of sirtuin... -
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- Effect of Collagen-Enhanced Fibrin Sealant on Seroma Formation in a Rat Mastectomy Model
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Kim JS, Eo PS, Lee JS, Lee JW, Choi KY, Chung HY, Cho BC, Lee J, Park HY, Yang JD
- KMID: 2511189
- J Wound Manag Res.
- 2020 Oct;16(3):137-143.
- doi: 10.22467/jwmr.2020.01242
Background: Seromas are caused by leakage of lymphovascular fluid into postoperative dead space. This is the most common complication after reconstructive breast surgery. The purpose of this study is to... -
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- Erratum: Advantages of Distal Subtotal Gastrectomy Over Total Gastrectomy in the Quality of Life of Long-Term Gastric Cancer Survivors
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Kwon OK, Yu B, Park KB, Park JY, Lee SS, Chung HY
- KMID: 2507039
- J Gastric Cancer.
- 2020 Sep;20(3):344-344.
- doi: 10.5230/jgc.2020.20.e31
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- Correction of microtia with constriction features using a superficial temporal fascial flap combined with a rib cartilage graft
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Lee JS, Kim JS, Lee JW, Choi KY, Yang JD, Chung HY, Cho BC
- KMID: 2504622
- Arch Plast Surg.
- 2020 Jul;47(4):317-323.
- doi: 10.5999/aps.2018.01165
Background Microtia with constricted features is characterized by a short helical length of variable severity, upper antihelical or scaphal deficiency, and a downfolded upper ear. No consensus has been reached... -
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- Advantages of Distal Subtotal Gastrectomy over Total Gastrectomy in the Quality of Life of Long-Term Gastric Cancer Survivors
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Kwon OK, Yu B, Park KB, Park JY, Lee SS, Chung HY
- KMID: 2503599
- J Gastric Cancer.
- 2020 Jun;20(2):176-189.
- doi: 10.5230/jgc.2020.20.e17
Purpose: This study evaluated differences and shifting patterns in the health-related quality of life (HRQoL) of 5-year gastric cancer survivors after either a distal subtotal gastrectomy (DSG) or total gastrectomy... -
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- Polarization of M2 Macrophages by Interaction between Prostate Cancer Cells Treated with Trichomonas vaginalis and Adipocytes
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Chung HY, Kim JH, Han IH, Ryu JS
- KMID: 2505089
- Korean J Parasitol.
- 2020 Jun;58(3):217-227.
- doi: 10.3347/kjp.2020.58.3.217
Trichomonas vaginalis causes inflammation of the prostate and has been detected in tissues of prostate cancers (PCa), prostatitis and benign prostatic hyperplasia. Obesity is a risk factor for PCa and... -
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- Information-Stressors and Cancer Patients’ Quality of Life: Responses to Deviant Information-Stressors Due to Pre-Postoperative Stage Discordance
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Lee SS, Chung HY, Kwon OK
- KMID: 2500833
- Chonnam Med J.
- 2020 May;56(2):108-114.
- doi: 10.4068/cmj.2020.56.2.108
This study assessed preoperative quality of life (QoL) of gastric cancer patients exposed to inconsistent illness information by pre-post-operative stage discordance. The impact of information-stressors on patients’ QoL was investigated... -
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