- Integrated analysis of copy number alteration and RNA expression profiles of cancer using a high-resolution whole-genome oligonucleotide array
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Jung SH, Shin SH, Yim SH, Choi HS, Lee SH, Chung YJ
- KMID: 1058020
- Exp Mol Med.
- 2009 Jul;41(7):462-470.
- doi: 10.3858/emm.2009.41.7.051
Recently, microarray-based comparative genomic hybridization (array-CGH) has emerged as a very efficient technology with higher resolution for the genome-wide identification of copy number alterations (CNA). Although CNAs are thought to... -
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- Heterozygosities of 735 microsatellite markers and background linkage disequilibrium in the Korean population
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Lee KA, Kim JW
- KMID: 1115944
- Exp Mol Med.
- 2006 Dec;38(6):662-667.
Suitability of a specific population for linkage disequilibrium mapping studies of complex traits may be assessed by investigating the background linkage disequilibrium (BLD). We are unaware of studies for quantifying... -
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- Analysis of genetic and non-genetic factors that affect the QTc interval in a Mongolian population: the GENDISCAN study
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Im SW, Lee MK, Lee HJ, Oh SI, Kim HL, Sung J, Cho SI, Seo JS, Kim JI
- KMID: 1122285
- Exp Mol Med.
- 2009 Nov;41(11):841-848.
- doi: 10.3858/emm.2009.41.11.090
The QTc interval is a complex quantitative trait and a strong prognostic indicator of cardiovascular mortality in general, healthy people. The aim of this study was to identify non-genetic factors... -
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- Amniotic Fluid Interphase Fluorescence in situ Hybridization (FISH) for Detection of Aneuploidy;Experiences in 130 Prenatal Cases
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Lim HJ, Kim YJ, Yang JH, Kim EJ, Choi JS, Jung SH, Ahn HK, Han JY, Kim MY, Choi KH, Kim JM, Kim YM, Park SY, Ryu HM
- KMID: 1127246
- J Korean Med Sci.
- 2002 Oct;17(5):589-592.
- doi: 10.3346/jkms.2002.17.5.589
The major aneuploidies diagnosed prenatally involve the autosomes 13, 18, 21, and sex chromosomes X and Y. Fluorescence in situ hybridization (FISH) allows rapid analysis of chromosome copy number... -
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