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Real-time PCR analysis of the apoptosis related genes in ATRA treated APL t(15;17) patients

Savli H, Sirma S, Nagy B, Aktan M, Dincol G, Ozbek U

  • KMID: 1093619
  • Exp Mol Med.
  • 2003 Oct;35(5):454-459.
All-trans retinoic acid (ATRA) treatment of the acute promyelocytic leukemia (APL) have subsequently resulted in cell apoptosis, but the molecular mechanism of this effect remains elusive. In order to understand...
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The effect of isochromosome 17q presence, proliferative and apoptotic indices, expression of c-erbB-2, bcl-2 and p53 proteins on the prognosis of medulloblastoma

Nam DH, Wang KC, Kim YM, Chi JG, Kim SK, Cho BK

Medulloblastoma accounts for 20 to 25+ACU- of all intracranial neoplasms in children. The significance of the presence of isochromosome 17q (i(17q)), proliferative potential, apoptotic activity, and expression of c-erbB-2, bd-2,...
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