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The Inhibitory Effect of Methotrexate-Layered Double Hydroxide (LDH) Hybrid on Osteosarcoma Cell Lines

Jeong J, Kang YK, Song HW, Han OJ, Ok IY, Jung JS, Oh JM, Park TU, Choy JH

  • KMID: 2106032
  • J Korean Orthop Assoc.
  • 2004 Feb;39(1):56-62.
PURPOSE: The purpose of this study was to observe and analyze the effect of Methotrexate-Layered Double Hydroxide (LDH) hybrids on growth inhibition and the apoptosis of human osteosarcoma cell lines...
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Alendronate-Anionic Clay Nanohybrid for Enhanced Osteogenic Proliferation and Differentiation

Piao H, Kim MH, Cui M, Choi G, Choy JH

BACKGROUND: Alendronate (AL), a drug for inhibiting osteoclast-mediated bone-resorption, was intercalated into an inorganic drug delivery nanovehicle, layered double hydroxide (LDH), to form a new nanohybrid, AL-LDH, with 1:1 heterostructure...
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