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A ROCK Inhibitor Blocks the Inhibitory Effect of Chondroitin Sulfate Proteoglycan on Morphological Changes of Mesenchymal Stromal/Stem Cells into Neuron-Like Cells

Lim HS, Joe YA

  • KMID: 2170662
  • Biomol Ther.
  • 2013 Nov;21(6):447-453.
Chondroitin sulfate proteoglycan (CSPG) inhibits neurite outgrowth of various neuronal cell types, and CSPG-associated inhibition of neurite outgrowth is mediated by the Rho/ROCK pathway. Mesenchymal stromal/stem cells (MSCs) have the...
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Expression of Hyaluronidase-4 in a Rat Spinal Cord Hemisection Model

Tachi Y, Okuda T, Kawahara N, Kato N, Ishigaki Y, Matsumoto

STUDY DESIGN: Examination of hyaluronidase-4 (Hyal-4) expression in a rat spinal cord hemisection model. PURPOSE: To determine the status of Hyal-4 expression after hemisection of the spinal cord, and the relationship...
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Effective Keratocyte Culture Using Amniotic Membrane Matrix and Differentiation of Mesenchymal Stem Cells

Park SH, Chun YS, Kim JC

  • KMID: 2337906
  • J Korean Ophthalmol Soc.
  • 2010 Dec;51(12):1652-1658.
PURPOSE: To investigate the characteristics of cultured rabbit corneal keratocytes in vitro and evaluate the possibility of differentiation of mesenchymal stem cells to keratocytes using the keratocyte conditioned medium (KCM). METHODS:...
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The Effect of Methylprednisolone and Riluzole on Axonal Growth after Acute Spinal Cord Injury in Rats

Hong CH, Yang JY, Lee JK, Song HS

  • KMID: 2336176
  • J Korean Orthop Assoc.
  • 2008 Dec;43(6):783-790.
PURPOSE: To determine the effect of methylprednisolone (MP) and riluzole administration on axonal growth after spinal cord injury (SCI) in rats. MATERIALS AND METHODS: Three Sprague Dawley rats (SD rat) served...
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A Model of Glial Scarring Analogous to the Environment of a Traumatically Injured Spinal Cord Using Kainate

Yoo JY, Hwang CH, Hong HN

OBJECTIVE: To develop an in vitro model analogous to the environment of traumatic spinal cord injury (SCI), the authors evaluated change of astrogliosis following treatments with kainate and/or scratch, and...
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