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Protective Action of Purinergic and Cholinergic Agonists on the Ischemic Myocardium in the Rat

Kim JH, Park SD, Ju JM, Kook H, Cho JG, Park OK

BACKGROUND: Purinergic and cholinergic agonists elicit negative-inotropic and chronotropic effects, anticip-ating their protective action from the damage of overloaded myocardium. However, the actions of the agents during the ischemic insults...
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Existance of cholinergic and purinergic receptor on the detrusor muscle of rat urinary bladder

Choi TS, Kwon OC, Ha JH, Lee KY, Kim WJ

This study was aimed at investigation of the stimulatory innervations on the rat urinary bladder. Detrusor muscle strips of 15 mm long were suspended in isolated muscle chambers containing 1...
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Mechanism of action of pancreatic polypeptide (PP) on pancreatic exocrine secretion in isolated rat pancreas

Lee YL, Kwon HY, Park HS, Park HJ

  • KMID: 2285162
  • Korean J Physiol Pharmacol.
  • 1997 Feb;1(1):83-90.
Aim of this study was to investigate if pancreatic polypeptide (PP) reduced the insulin action via the intra-pancreatic cholinergic nerves in the isolated rat pancreas. The pancreas was isolated from rats and perfused...
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Pilocarpine Induced Expression of Nitric Oxide Synthase in R18A5 Retinal Ganglion Cell Line

Choi KD, Bae JH, Huh K, Chung JH

  • KMID: 2336932
  • J Korean Ophthalmol Soc.
  • 2000 Jul;41(7):1466-1472.
Pilocarpine is a direct cholinergic agonist and reduces intraocular pressure by enhancing aqueous outflow. A recent study reveals that pilocarpine induces apoptotic cell death in retinal ganglion cells; activation of...
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The Effects of Coadministration of Haloperidol and Bethanechol on Plasma Haloperidol and Reduced Haloperidol Concentrations

Kim HS, Ahn JY, Yeo UT, Jo SH

  • KMID: 1834629
  • J Korean Soc Biol Psychiatry.
  • 1998 Jun;5(1):114-121.
Bethanechol, a cholinergic agonist, has been recommended for the management of peripheral anticholinergic side effects during the treatment of antipsychotic medications. But there have been few studies which have evaluated...
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Drug Interactions of Intrathecal Carbachol and Clonidine in Neuropathic Pain Model of the Rats

Lee EJ, Lee YS, Hwang JH, Han SM

BACKGROUND: After peripheral nerve injury in human, a syndrome of events (spontaneous pain, allodynia and hyperalgesia) may be observed that includes no response of morphine and dependency of this pain...
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Fluid and amylase secretion by perfused parotid gland: physio-morphological approach

Murakami M, Yoshimura , Sugiya H, Segawa A, Loffredo F, Testa-Riva F, Riva A

Whole gland perfusion technique was applied to rat parotid glands to assess whether amylase affects fluid secretion. Control perfusion without any secretagogue evoked no spontaneous secretion. Carbachol (CCh 1 microM)...
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Electroacupuncture ameliorates experimental colitis induced by acetic acid in rat

Kang JW, Kim TW, La JH, Sung TS, Kim HJ, Kwon YB, Kim JY, Yang IS

  • KMID: 1099831
  • J Vet Sci.
  • 2004 Sep;5(3):189-195.
The effect of electroacupuncture (EA) on experimental colitis was investigated in Sprague-Dawley rats. Colitis was induced by intracolonic instillation of 4% acetic acid. EA (2 Hz, 0.05 ms, 2 V...
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Five subtypes of muscarinic receptors are expressed in gastric smooth muscles of guinea pig

So I, Yang DK, Kim HJ, Min KW, Kang TM, Kim SJ, Kim KW, Park KH, Jeon JH, Choi KH, Kim IG

  • KMID: 1088657
  • Exp Mol Med.
  • 2003 Feb;35(1):46-52.
Muscarinic receptors play key roles in the control of gastrointestinal smooth muscle activity. However, specific physiological functions of each subtype remain to be determined. In this study, the nonselective cation...
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