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Research Progress on Non-coding RNAs in Cholesteatoma of the Middle Ear

Liu D, zhang H, Ma X, Dong Y

Cholesteatoma of the middle ear is a common disease in otolaryngology that is receiving increasing attention. It is estimated that over five million people around the world have suffered from...
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Immunohistochemical Analysis of the Expression of Cytokeratins in Acquired Cholesteatoma and Its Clinico-Radiological Correlation

Kanodia A, Kakkar A, Verma Y, Roy D, Verma H, Singh CA, Monga R, Jain D, Thakar A, Sikka K

Background and Objectives: Cholesteatomatous chronic otitis media acquires epithelial proliferation and differentiation characteristics, which render it able to erode the underlying bone and cause complications. We attempt to characterize the...
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Chronic Meningitis Due to Otitis Media With Cholesteatoma in a Five-Year-Old Child With a Cochlear Implant

van Oorschot HD, Helleman HW, Smit AL

Cochlear implants (CIs) restore hearing in patients with severe-to-profound deafness. Post-CI meningitis is a rare but redoubted complication. We present the case of a five-year-old CI recipient who experienced an...
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Changes in Coagulation Study and Risk of Developing Cholesteatoma: Is There a Link?

Costa JR, Rego , Soares T, Sousa CAe, Coutinho MB

Background and Objectives: The etiopathogenesis of acquired pediatric cholesteatoma has not yet been fully clarified. Recent studies and modern technologies have led researchers to look for explanations at a molecular...
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Symmetric Bilateral Congenital Middle Ear Cholesteatoma: A Case Report

Hong JP, Kim MB

Congenital middle ear cholesteatoma (CMEC) accounts for 2%-5% of all cases of middle ear cholesteatoma. CMEC is rare and diagnostically challenging; therefore, only a few cases are reported in the...
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Assessment of the Vestibuloocular Reflex in Patients with Unilateral Chronic Middle Ear Disease Using the Video Head Impulse Test: A Preliminary Study

Nam GS, Baek W, Cho SI

Objectives: This study aims to investigate the usefulness of the video head impulse test (vHIT) as a method for evaluating vestibular function in patients with unilateral chronic middle ear disease. Methods:...
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Transcanal Endoscopic Ear Surgery with Piezoelectric Device for External Auditory Canal Lesions

Lee CY, Kim SH, Choi JH

External auditory canal exostosis (EACE) is prone to occur in patients frequently exposed to cold water, which causes earwax impaction, recurrent otitis externa, and conductive hearing loss. The main treatment...
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Simultaneous Treatment of Vestibular Schwannoma and Concurrent Middle Ear Disease Using the Enlarged Translabyrinthine Approach

Noh HE, Lee HY, Na G, Moon IS

Unilateral presentation of vestibular schwannoma with concurrent chronic middle ear disease or cholesteatoma is rare. We report a series of patients with ipsilateral chronic middle ear disease and vestibular schwannoma,...
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Surgical Outcome of Revision Operation for Recurrent Aural Cholesteatoma

Lee JS, Han JH, Hong SK, Lee HJ, Kim HJ

Background and Objectives To investigate surgical outcomes of revision operation for recurrent cholesteatoma. Subjects and Method From 1989 to 2018, 5245 cases of middle ear surgeries were performed at Kangdong and...
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Comparison of Autophagy mRNA Expression between Chronic Otitis Media With and Without Cholesteatoma

Jung J, Jung SY, Kim MG, Kim YI, Kim SH, Yeo SG

Background and Objectives: Autophagy is known to be associated with pathogen infection. However, the expression of autophagy-related proteins has not been studied in chronic otitis media without cholesteatoma (COM) or...
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Usefulness of a Novel Staging System for Congenital Cholesteatoma of the Middle Ear

Kim BJ, Han JH, Yang JH, Hong SK, Lee HJ, Kim HJ

BACKGROUND AND OBJECTIVES: Although there are number of studies on the risk factors of recidivism in the congenital middle ear cholesteatoma, few have focused on the staging system. In this...
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Management of Acquired Cholesteatoma Associated With Patulous Eustachian Tube and Habitual Sniffing

Choi SW, Lee DJ, Lee SH, Oh SJ, Kong SK

OBJECTIVES: To investigate the effect of surgical treatment with eustachian tube (ET) catheter insertion in patients with acquired cholesteatoma associated with patulous eustachian tube (PET) and habitual sniffing. METHODS: Nine ears...
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A Case of Cholesteatoma of Maxillary Sinus

Kim BM, Shin SH, Ye MK

Cholesteatoma is common disease entity within the middle ear cavity but is rarely found in the paranasal sinuses, especially the maxillary sinus. We experienced a case of cholesteatoma of the...
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Comparison of the Clinical Results of Attic Cholesteatoma Treatment: Endoscopic Versus Microscopic Ear Surgery

Bae MR, Kang WS, Chung JW

OBJECTIVES: We aimed to compare clinical outcomes including hearing improvement and cholesteatoma recurrence between endoscopic and conventional microscopic surgeries in patients with attic cholesteatoma. METHODS: We collected data from patients with...
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Transcanal Endoscopic Ear Surgery for Congenital Cholesteatoma

Park JH, Ahn J, Moon IJ

OBJECTIVES: As endoscopic instrumentation, techniques and knowledges have significantly improved recently, endoscopic ear surgery has become increasingly popular. Transcanal endoscopic ear surgery (TEES) can provide better visualization of hidden areas...
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Spontaneous migration of a congenital intratympanic membrane cholesteatoma

Kim TH, Lee KY, Jung DJ

Congenital intratympanic membrane cholesteatoma (ITMC) is a rare type of congenital cholesteatoma located within the tympanic membrane. This lesion tends to increase in size over time. The development of ITMC...
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Congenital Cholesteatoma of Mastoid Temporal Bone and Posterior Cranial Fossa Treated with Transmastoid Marsupialization

Sung CM, Yang HC, Cho YB, Jang CH

A congenital cholesteatoma is a benign mass formed from the keratinizing stratified squamous epithelium. It usually occurs in young children's anterosuperior part of the middle ear. A congenital cholesteatoma which...
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The Allele 2 of the VNTR Polymorphism in the Gene That Encodes a Natural Inhibitor of IL-1β, IL-1RA Is Favorably Associated With Chronic Otitis Media

Živković M, Kolić I, Jesić S, Jotić A, Stanković A

OBJECTIVES: Chronic otitis media (COM) is followed by irreversible tissue damage and destruction of the middle ear structures, with the possibility of complications under the maintenance of inflammation. Inflammatory mediators...
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Expression of Prostaglandin E2 Receptors in Acquired Middle Ear Cholesteatoma

Wang S, Xie L, Zhang Y, Xu P, Liu A

OBJECTIVES: To investigate the expression of prostaglandin E2 receptor subtypes, E-prostanoid (EP) 1–4 receptors, in acquired cholesteatoma and its possible role in the pathologic process of this disorder. METHODS: Specimens of...
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Congenital Cholesteatoma: Analysis of Risk Factors for the Postoperative Recurrence

Oh YS, Kim JM, Jung HJ, Shin SO, Choi YS

BACKGROUND AND OBJECTIVES: The incidence of recurrence after surgery of congenital cholesteatoma is increasing due to the widespread use of otoendoscopy as well as an increased awareness of these lesions...
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