- Safety Assessment of Octylmethoxycinnamate, Butylmethoxydibenzoylmethane, and Octyltriazone Sunscreens by Human Repeated Insult Patch Tests to Compare the Shelanski and Maximization Tests
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Choi J, Chey WY, Lee AY
- KMID: 1977851
- Korean J Dermatol.
- 2003 Dec;41(12):1592-1596.
BACKGROUND: Human repeated insult patch tests (HRIPTs) are a final method for safety assessment of chemical ingredients. In the representative HRIPTs, the Shelanski and modified Draize require 200 participants, but... -
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- Safety and Efficacy of Itraconazole for the Treatment of Onychomycosis in the Diabetic Population
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Chey WY, Kim YG, Chung EC, Lee AY
- KMID: 2303113
- Korean J Dermatol.
- 2002 Aug;40(8):890-896.
INTRODUCTION: As the number of diabetics increase with younger onset and longer duration, patients are confronted with higher incidence of diabetes related complications such as distal extremity vasculopathy, neuropathy and... -
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- Constitutive expression and changes of cytochrome P450 isozymes mRNAs by vehicles (petrolatum, DMSO, ethanol) in rat skin using semi-quantitative RT-PCR
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Lee AY, Lee KH, Ko DS, Chey WY
- KMID: 1607080
- Korean J Physiol Pharmacol.
- 2001 Oct;5(5):407-412.
Many drugs are primarily metabolized by the cytochrome P450s (CYPs). Drug metabolites would be important allergens for adverse drug reactions such as drug eruptions. Skin tests with a suspected drug have conducted to... -
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- Studies for Pathogenesis of Fixed Drng Emptions Through the Change of Cytochrome p450 Isozymes
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Lee AY, Kim MJ, Lee KE, Chey WY, Choi J
- KMID: 2250974
- Korean J Dermatol.
- 2001 Nov;39(11):1246-1252.
The reasons of same site recurrence in fixed drug eruptions (FDEs) remain to be clarified. Although the nature of antigen in FDE is unknown, drug metabolites could play a role... -
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- Involvement of Crosstalk Between cAMP and cGMP in Synaptic Plasticity in the Substantia Gelatinosa Neurons
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Kim TH, Chung G, Park SB, Chey WY, Jung SJ, Kim JS, Oh SB
- KMID: 2170737
- Int J Oral Biol.
- 2011 Jun;36(2):83-89.
Substantia gelatinosa (SG) neurons receive synaptic inputs from primary afferent Adelta- and C-fibers, where nociceptive information is integrated and modulated by numerous neurotransmitters or neuromodulators. A number of studies were... -
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