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Intracranial Atherosclerosis: From Microscopy to High-Resolution Magnetic Resonance Imaging

Yang WJ, Wong KS, Chen XY

Intracranial atherosclerosis is one of the leading causes of ischemic stroke and occurs more commonly in patients of Asian, African or Hispanic origin than in Caucasians. Although the histopathology of...
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Association of Visit-to-Visit Variability of Blood Pressure with Cardiovascular Disease among Type 2 Diabetes Mellitus Patients: A Cohort Study

Yu ZB, Li D, Chen XY, Zheng PW, Lin HB, Tang ML, Jin MJ, Wang JB, Chen K

BACKGROUND: Increasing evidence has shown that visit-to-visit variability (VVV) of blood pressure (BP) is associated with an increased risk of cardiovascular disease (CVD). The objective of this study was to...
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Intracranial Artery Calcification and Its Clinical Significance

Wu XH, Chen XY, Wang LJ, Wong KS

Intracranial arterial calcification (IAC) is an easily identifiable entity on plain head computed tomography scans. Recent studies have found high prevalence rates for IAC worldwide, and this may be associated...
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Correlation of Adventitial Vasa Vasorum with Intracranial Atherosclerosis: A Postmortem Study

Zheng L, Yang WJ, Niu CB, Zhao HL, Wong KS, Leung TW, Chen XY

BACKGROUND AND PURPOSE: Vasa vasorum (VV) have been believed to be rare or non-existent in small-caliber intracranial arteries. In a series of human cerebral artery specimens, we identified and examined...
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Gene-metabolite network analysis in different nonalcoholic fatty liver disease phenotypes

Liu XL, Ming YN, Zhang JY, Chen XY, Zeng MD, Mao YM

We sought to identify common key regulators and build a gene-metabolite network in different nonalcoholic fatty liver disease (NAFLD) phenotypes. We used a high-fat diet (HFD), a methionine-choline-deficient diet (MCDD)...
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