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Bioactive metabolites: A clue to the link between MASLD and CKD?

Chen WY, Zhang JH, Chen LL, Byrne CD, Targher G, Luo L, Ni Y, Zheng MH, Sun DQ

Metabolites produced as intermediaries or end-products of microbial metabolism provide crucial signals for health and diseases, such as metabolic dysfunction-associated steatotic liver disease (MASLD). These metabolites include products of the...
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Interleukin-20 targets podocytes and is upregulated in experimental murine diabetic nephropathy

Hsu YH, Li HH, Sung JM, Chen WY, Hou YC, Weng YH, Lai WT, Wu CH, Chang MS

Interleukin (IL)-20, a proinflammatory cytokine of the IL-10 family, is involved in acute and chronic renal failure. The aim of this study was to elucidate the role of IL-20 during...
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