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How to Achieve a Higher Pathologic Complete Response in Patients With Locally Advanced Rectal Cancer Who Receive Preoperative Chemoradiation Therapy

Lee SH

The current standard of care for treating patients with locally advanced rectal cancer includes preoperative chemoradiation therapy (PCRT) followed by a total mesorectal excision and postoperative adjuvant chemotherapy. A subset...
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Pancreas club international joint symposium on pancreatic cancer 2012, Kyoto: down staging chemo+/-radiotherapy for borderline resectable pancreatic cancer

Kang CM, Hwang HK, Lee WJ

This manuscript summarized one section out of the international symposium, Pancreatic Cancer 2012, which was held last October 4th through 6th in Kyoto (Japan) under the theme, "We are the...
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Prognosis of stage IIB cervical cancer among treatment regimens: Radical hysterectomy vs. neoadjuvant chemotherapy followed by radical hysterectomy vs. concurrent chemoradiotherapy

Woo YJ, Byun JM, Jeong DH, Kim YN, Kim SS, Seo YJ, Sung MS, Lee KB, Kim KT

OBJECTIVE: We aimed to compare the prognosis of patients with stage IIB cervical cancer treated with radical hysterectomy alone, with neoadjuvant chemotherapy followed by radical hysterectomy, and with concurrent chemoradiation...
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Primary squamous cell carcinoma arising from the pelvic retroperitoneum

Ryu MJ, Chung YW, Bae HS, Lee JK, Lee NW, Song JY

  • KMID: 2393155
  • Korean J Obstet Gynecol.
  • 2012 Oct;55(10):782-786.
Primary retroperitoneal squamous cell carcinoma is very rare. A 66-year-old woman presented with right leg edema and pain that had developed one month prior. Pelvis magnetic resonance imaging showed the...
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Update and Debate Issues in Surgical Treatment of Middle and Low Rectal Cancer

Kim NK, Kim MS, AL-Asari S

Based on a review of the literature, this paper provides an update on surgical treatment of middle and low rectal cancer and discusses issues of debate surrounding that treatment. The...
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Comparison of concurrent chemoradiation therapy with weekly cisplatin versus monthly fluorouracil plus cisplatin in FIGO stage IIB-IVA cervical cancer

Kong TW, Chang SJ, Paek J, Yoo SC, Yoon JH, Chang KH, Chun M, Ryu HS

OBJECTIVE: Concurrent chemoradiation therapy (CCRT) is the standard treatment for locally advanced cervical cancer. Although the optimal chemotherapeutic regimen is not yet defined, previous randomized trials have demonstrated that 5-fluorouracil...
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Comparison of outcomes between radical hysterectomy followed by tailored adjuvant therapy versus primary chemoradiation therapy in IB2 and IIA2 cervical cancer

Park JY, Kim DY, Kim JH, Kim YM, Kim YT, Kim YS, Kim HJ, Lee JW, Kim BG, Bae DS, Huh SJ, Nam JH

OBJECTIVE: To compare survival outcomes and treatment-related morbidities between radical hysterectomy (RH) and primary chemoradiation therapy (CRT) in patients with bulky early-stage cervical cancer. METHODS: We selected 215 patients with stage...
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Variable uterine uptake of FDG in adenomyosis during concurrent chemoradiation therapy for cervical cancer

Yu JI, Huh SJ, Kim YI, Kim TJ, Park BK

To avoid improper tumor volume contouring in radiation therapy (RT) and other invasive procedures, we report a case of uterine adenomyosis showing increased 18F-fluorodeoxyglucose (FDG) uptake on positron emission tomography...
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Abdominoperineal Resection in the Treatment of Locally-advanced Low Rectal Cancer: Is Preoperative Chemoradiation Advantageous?

Kim JY, Kim JS, Kim YW, Hur H, Min BS, Kim NK

PURPOSE: An abdominoperineal resection (APR) has a poor prognosis. However, limited studies about the prognostic factors in APR and the role of preoperative chemoradiotherapy (CRT) have been performed even though...
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Clinicopathologic Characteristics of Anal Cancer

Kim SH, Kim HJ, Lee JI, Kye BH, Lee IK, Lee YS, Kang WK, Kim JG, Oh ST

PURPOSE: This study was performed to evaluate clinicopathologic features in anal canal carcinoma. METHODS: Among the 43 patients who were diagnosed with anal cancer at Kangnam St. Mary's Hospital, from June...
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Clinical significance of tumor volume and lymph node involvement assessed by MRI in stage IIB cervical cancer patients treated with concurrent chemoradiation therapy

Lee DW, Kim YT, Kim JH, Kim S, Kim SW, Nam EJ, Kim JW

OBJECTIVE: The purpose of this study was to evaluate the prognostic significance of tumor volume assessed by pretreatment MRI in stage IIB cervical cancer patients with concurrent chemoradiation therapy. METHODS:...
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Long-Term Results of 2-Dimensional Radiation Therapy in Patients with Nasopharyngeal Cancer

Lee NK, Park YJ, Yang DS, Yoon WS, Lee S, Kim CY

PURPOSE: To analyze the treatment outcomes, complications, prognostic factors after a long-term follow-up of patients with nasopharyngeal carcinoma treated with radiation therapy (RT) alone or concurrent chemoradiation therapy (CCRT). MATERIALS AND...
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The Usefulness of 18F-FDG PET/CT for Predicting the Response of Locally Advanced Rectal Cancer to Neoadjuvant Chemoradiation Therapy

Kang JK, Kim MS, Choi CW, Jeong SY, Yoo SY, Cho CK, Yang KM, Yoo HJ, Cheon GJ, Shin YJ, Seo YS

PURPOSE: This study aimed at assessing the value of fluorine-18 fluorodeoxyglucose positron emission tomography (18F-FDG PET) for predicting the response of locally advanced rectal cancer to neoadjuvant CRT. MATERIALS AND METHODS:...
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Oncologic Result as According to Tumor Regression Grade after Neoadjuvant Chemoradiation Therapy in Locally Advanced Rectal Cancer

Park JH, Song MS, Min HS, Kim JY

PURPOSE: The effects of neoadjuvant chemoradiation therapy (NCRT) in cases of locally advanced rectal cancer include tumor downstaging with respect to a curative resection and a decreasing incidence of local...
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Concurrent chemoradiation therapy in cervical cancer with para-aortic lymph node involvement

Shin JW, Lee KC, Lee SH, Choi JH, Lee KB, Park CY

  • KMID: 2244561
  • Korean J Gynecol Oncol.
  • 2007 Jun;18(2):108-113.
OBJECTIVE: This study was undertaken to evaluate the therapeutic results and complications after concurrent chemoradiation therapy and to investigate the prognostic factors for cervical cancer with para-aortic lymph node involvement....
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Preliminary Results of Concurrent Chemotherapy and Radiation Therapy using High-dose-rate Brachytherapy for Cervical Cancer

Lee KJ, Lee J, Lee R, Suh H

  • KMID: 1512293
  • J Korean Soc Ther Radiol Oncol.
  • 2006 Sep;24(3):171-178.
PURPOSE: To determine the efficacy and safety of concurrent chemotherapy and radiation therapy with high-dose-rate brachytherapy for cervical cancer. MATERIALS AND METHODS: From January 2001 to December 2002, 30 patients...
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Recent Management of FIGO stage IB2 Cervical Cancer

Chung HH, Kim JW

  • KMID: 2272671
  • Korean J Obstet Gynecol.
  • 2005 Sep;48(9):2057-2066.
The treatment of patients with bulky stage IB2 cervical cancer is a therapeutic challenge. Neither of local treatment such as radical hysterectomy nor primary radiation therapy is sufficiently effective, and...
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Impact of Adjuvant Chemoradiation Therapy on the Postoperative 5-year Survival Rates for Stage-II Gastric Cancer

Hong SK, Choi MG, Baik YH, Noh JH, Sohn TS, Kim S

  • KMID: 2372794
  • J Korean Gastric Cancer Assoc.
  • 2005 Dec;5(4):281-287.
PURPOSE: This study was conducted to evaluate the effectiveness and the role of post-operative adjuvant chemoradiation therapy in a stage-II (UICC,1997) primary gastric cancer. MATERIALS AND METHODS: From September 1994 to...
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Transanal Endoscopic Microsurgery after Preoperative Concurrent Chemoradiation Therapy in Selected Distal Rectal Cancer Patients

Park CM, Jung KW, Han SA, Yun SH, Lee WY, Chun H

  • KMID: 1944700
  • J Korean Soc Coloproctol.
  • 2005 Oct;21(5):293-299.
PURPOSE: Preoperative concurrent chemoradiation (CCRT) therapy may allow higher rates of tumor resectability and sphincter-saving procedures. Transanal endoscopic microsurgery (TEM) has become increasingly common in the management of selected patients...
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Intersphincteric Resection for Very Low Rectal Cancer

Kim JH, Oh NG

  • KMID: 1944722
  • J Korean Soc Coloproctol.
  • 2004 Dec;20(6):364-370.
PURPOSE: In the treatment of rectal cancer, sphincter saving resection is increased but low anterior resection is limited in treatment for low rectal cancer below 4 cm from the anal...
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