- Effects of cytochrome P450 3A5 (CYP3A5) on pharmacokinetic profiles of tacrolimus in Thai patients with liver transplantation
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Vorasittha A, Chariyavilaskul P, Tanathitiphuwarat N, Noonthasoot B
- KMID: 2535714
- Korean J Transplant.
- 2022 Nov;36(Supple 1):S198.
- doi: 10.4285/ATW2022.F-3323
Background: Tacrolimus, an immunosuppressant used in liver transplant patients, has narrow therapeutic index and large inter-individual pharmacokinetic variability, partly due to the pharmacogenetic variation in the main drug-metabolizing enzyme cytochrome... -
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