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A “Prime and Deploy” Strategy for Universal Influenza Vaccine Targeting Nucleoprotein Induces Lung-Resident Memory CD8 T cells

Chung H, Kim EA, Chang J

Lung-resident memory T cells (TRM ) play an essential role in protecting against pulmonary virus infection. Parenteral administration of DNA vaccine is generally not sufficient to induce lung CD8 T...
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The Association between Behavioral Risk Factors and Nontuberculous Mycobacterial Pulmonary Disease

Park Y, Kwak SH, Yong SH, Lee SH, Leem AY, Kim SY, Lee SH, Chung K, Kim EY, Jung JY, Park MS, Kim YS, Chang J, Kang YA

Purpose: We aimed to determine the relationship between environmental exposure and nontuberculous mycobacterial pulmonary disease (NTM-PD) in Korea. Materials and Methods: A group of 150 patients with NTM-PD and a control...
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Hearing Impairment Increases Economic Inequality

Kim SY, Min C, Yoo DM, Chang J, Lee HJ, Park B, Choi HG

Objectives. We evaluated changes in income levels in a hearing-impaired population. Methods. The study subjects were selected from the Korean National Health Insurance Service-Health Screening Cohort data from 2002 to 2015...
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Characteristics and risk factors associated with missed diagnosis in patients with smear-negative pulmonary tuberculosis

Kwak SH, Choi JS, Lee EH, Lee SH, Leem AY, Lee SH, Kim SY, Chung KS, Jung JY, Park MS, Kim YS, Chang J, Kang YA

Background/Aims: Delayed diagnosis and treatment of smear-negative pulmonary tuberculosis (TB) are major concerns for TB control. We evaluated characteristics of patients with smear-negative pulmonary TB who received a delayed diagnosis...
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Adenovirus Vectors: Excellent Tools for Vaccine Development

Chang J

Adenovirus was originally used as a vector for gene therapy. In recent years, with the development of the next-generation vectors with increased safety and high immunogenicity to transgene products, its...
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Development and validation of prediction equations for the assessment of muscle or fat mass using anthropometric measurements, serum creatinine level, and lifestyle factors among Korean adults

Lee G, Chang J, Hwang Ss, Son JS, Park SM

BACKGROUND/OBJECTIVES: The measurement of body composition, including muscle and fat mass, remains challenging in large epidemiological studies due to time constraint and cost when using accurate modalities. Therefore, this study...
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Accuracy of conventional and digital mounting of dental models: A literature review

Kim C, Ji W, Chang J, Kim S

Accurate transfer of the maxillo-mandibular relationship to an articulator (i.e., mounting) is critical in prosthetic treatment procedures. In the current study, a PubMed search was performed to review the influencing...
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Association between Harms from the Alcohol Consumption of Others and Depression, Stress among Korean Adults

Kim JE, Chang J, Kim SJ

Background: The purpose of this study is to investigate association between harms from the alcohol consumption of others and depression measured by Patient Health Questionnaire-9, perceived stress among Korean adults. Methods:...
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Clinical Features of Chronic Obstructive Pulmonary Disease with High Fractional Exhaled Nitric Oxide

Ahn S, Kim TO, Chang J, Shin HJ, Kwon YS, Lim SC, Kim YI

Background: The fractional exhaled nitric oxide (FENO) test is useful in asthma patients. However, a few studies on its usefulness in chronic obstructive pulmonary disease (COPD) patients have been reported....
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Emergence of optrA-Mediated Linezolid-Nonsusceptible Enterococcus faecalis in a Tertiary Care Hospital

Park K, Jeong YS, Chang J, Sung H, Kim MN

This study investigated resistance mechanisms and epidemiology of emerging linezolid-nonsusceptible Enterococcus faecalis (LNSEF) in a tertiary care hospital. LNSEF isolated from clinical samples were collected from November 2017 to June...
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Comparison of clinical outcomes according to the history of previous gastrectomy in patients undergoing pancreatoduodenectomy: a propensity score matching analysis

Kim JR, Kwon W, Chang J, Jang JY, Kim SW

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Is percutaneous dilatational tracheostomy with bronchoscopic guidance better than without?

Chang J, Shin HJ, Kwon YS, Kim YI, Lim SC, Kim TO

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Predictors and outcomes of sepsis-induced cardiomyopathy in critically ill patients

Song MJ, Lee SH, Leem AY, Kim SY, Chung KS, Kim EY, Jung JY, Kang YA, Kim YS, Chang J, Park MS

Background: Sepsis-induced cardiomyopathy (SIC) occurs frequently in critically ill patients, but the clinical features and prognostic impact of SIC on sepsis outcome remain controversial. Here, we investigated the predictors and...
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Corrosive Esophageal Injury due to a Commercial Vinegar Beverage in an Adolescent

Chang J, Han SE, Paik SS, Kim YJ

Although gastroesophageal damage is commonly induced by accidental drinking of a strong acid or alkali, damage due to the consumption of a vinegar beverage is not well known. We report...
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Comparison of clinical outcomes according to the history of previous gastrectomy in patients undergoing pancreatoduodenectomy: a propensity score matching analysis

Kim JR, Kwon W, Chang J, Jang JY, Kim SW

Purpose: Although pancreatoduodenectomy (PD) in patients who have previously undergone gastrectomy is challenging, little is known about the clinical outcomes and the differences compared to those with conventional PD. We...
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Risk Factors Associated with Failure of Cephalomedullary Nail Fixation in the Treatment of Trochanteric Hip Fractures

Yoo J, Chang J, Park C, Hwang J

BACKGROUND: Intramedullary (IM) nailing is widely performed in elderly patients with trochanteric fractures. Thus, it is important to identify causative factors associated with fixation failure. We investigated fixation failures after...
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The role of bilirubin to albumin ratio as a predictor for mortality in critically ill patients without existing liver or biliary tract disease

Choi JS, Chung KS, Lee EH, Lee SH, Lee SH, Kim SY, Jung JY, Kang YA, Park MS, Kim YS, Chang J, Leem AY

Background: Hyperbilirubinemia and hypoalbuminemia are frequently appeared and associated with poor prognosis in critically ill patients. We aim to evaluate the association between the bilirubin to albumin ratio and prognosis...
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Characteristics and Treatment Outcomes of Isoniazid Mono-Resistant Tuberculosis: A Retrospective Study

Kwak SH, Choi JS, Lee EH, Lee SH, Leem AY, Lee SH, Kim SY, Chung KS, Kim EY, Jung JY, Park MS, Kim YS, Chang J, Kang YA

Purpose: Isoniazid (INH) mono-resistant tuberculosis (Hr-TB) is a highly prevalent type of drug-resistant TB, possibly associated with unfavorable treatment outcomes. However, definitive guidelines on an optimal treatment regimen and duration...
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Age- and sex-related characteristics of the increasing trend of nontuberculous mycobacteria pulmonary disease in a tertiary hospital in South Korea from 2006 to 2016

Park Y, Kim CY, Park MS, Kim YS, Chang J, Kang YA

Background/Aims: The incidence rate of nontuberculous mycobacterial pulmonary disease (NTM-PD) is increasing worldwide. However, data regarding the age- and sex-specific epidemiology of NTM-PD are limited. This study aimed to investigate...
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Hippo Signal Transduction Mechanisms in T Cell Immunity

Bouchard A, Mariko M, Chang J, Panneton V, Li J, Bouklouch Y, Suh WK

Hippo signaling pathways are evolutionarily conserved signal transduction mechanisms mainly involved in organ size control, tissue regeneration, and tumor suppression. However, in mammals, the primary role of Hippo signaling seems...
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