- Detection of Bacillus anthracis using a nested PCR Method
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Choi YK, Cho SK, Kim MH, Baik SY, Park GH, Chai YG
- KMID: 2146918
- J Korean Soc Microbiol.
- 1998 Dec;33(6):583-588.
Bacillus anthracis is a soil pathogen capable of causing anthrax in animals and humans. To establish a method for specifically detecting B. anthracis, we used nested polymerase chain reaction. Outer... -
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- An Association Study of COMT Gene Polymorphism with Korean Schizophrenics
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Song ES, Chai YG, Yang BH, Park KK, Oh DY, Kim GS, Lee YS, An ES, Kim JW, Choi IG
- KMID: 2334569
- J Korean Soc Biol Psychiatry.
- 1998 Nov;5(2):210-214.
An association study with Korean schizophrenic patients(N=84) and normal controls(N=87) was performed to find the relationship between catechol-o-methyltransferase(COMT) gene polymorphism and schizophrenia using polymerase chain reaction-restriction fragment length polymorphism. When... -
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- Purification of the Protective Antigen from Bacillus anthracis
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Park JM, Choi YK, Cho SK, Chai YG, Kim SJ
- KMID: 2146919
- J Korean Soc Microbiol.
- 1998 Dec;33(6):589-594.
Anthrax toxin consists of three separate proteins, protective antigen (PA), edema factor (EF), and lethal factor (LF). PA binds to the receptor on mammalian cells and facilitates translocation of EF... -
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- C-fos mRNA Expression in Rat Hippocampal Neurons by Antidepressant Drugs
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Park EC, Cho YG, Yang BH, Kim KI, Yang BG, Chai YG
- KMID: 2142163
- J Korean Soc Biol Psychiatry.
- 2001 Jun;8(1):85-95.
This study was designed to examine the effects of two antidepressant drugs on the expression of c-fos mRNA in cultured embryonic rat hippocampal neurons. The drugs used were imipramine and... -
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- Cell Beath Induced by Ethanol : Prevention of Cell Death by the bcl-2 Proto-Oncogene
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Lim EJ, Hong KJ, Yang BH, Chai YG
- KMID: 2202982
- J Korean Soc Biol Psychiatry.
- 1997 Nov;4(2):211-218.
The Bcl-2 protein has been shown to block apoptosis induced by a variety of stimuli. We have performed the experiments which cell death can be blocked by the bcl-2 proto-oncogene... -
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- Genetic diversity of Korean Bacillus anthracis isolates from soil evaluated with a single nucleotide repeat analysis
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Kim SH, Jung KH, Kim SK, Kim SJ, Kim JC, Cho SY, Chai JC, Lee YS, Kim YK, Hwang HC, Ryu SG, Chai YG
- KMID: 1712313
- J Vet Sci.
- 2013 Dec;14(4):457-465.
- doi: 10.4142/jvs.2013.14.4.457
Bacillus (B.) anthracis, the etiological agent of anthrax, is one of the most genetically monomorphic bacteria species in the world. Due to the very limited genetic diversity of this species,... -
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- Genetic populations of Bacillus anthracis isolates from Korea
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Jung KH, Kim SH, Kim SK, Cho SY, Chai JC, Lee YS, Kim JC, Kim SJ, Oh HB, Chai YG
- KMID: 2391997
- J Vet Sci.
- 2012 Dec;13(4):385-393.
Bacillus (B.) anthracis is the pathogen that causes fatal anthrax. Strain-specific detection of this bacterium using molecular approaches has enhanced our knowledge of microbial population genetics. In the present study,... -
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- Cytosine Arabinoside-Induced PC12 Cell Death Pathway
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Yang BG, Chai YG, Yang BH
- KMID: 2334571
- J Korean Soc Biol Psychiatry.
- 1998 Nov;5(2):219-226.
Cytosine arabinoside(AraC) inhibits DNA synthesis and beta-DNA polymerase, an enzyme involved in DNA repair. This a potent antimitotic agent, is clinically used as an anticancer drug with side effect of... -
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- Induction of Apoptosis in Synovial Cells from Patients with Rheumatoid Arthritis
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Chang SY, Kim SY, Kim MH, Chai YG, Park JC, Choi YK, Jun JB, Jung SS
- KMID: 1548386
- Korean J Immunol.
- 1997 Dec;19(4):609-616.
Homeostasis of multicellular organism is controlled by proliferation and differentiation of cells as well as by cell death. The defects in programmed cell death contribute to the pathogenesis of rheumatoid... -
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- Genome-scale DNA methylation pattern profiling of human bone marrow mesenchymal stem cells in long-term culture
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Choi MR, In YH, Park J, Park T, Jung KH, Chai JC, Chung MK, Lee YS, Chai YG
- KMID: 1387361
- Exp Mol Med.
- 2012 Aug;44(8):503-512.
Human bone marrow mesenchymal stem cells (MSCs) expanded in vitro exhibit not only a tendency to lose their proliferative potential, homing ability and telomere length but also genetic or epigenetic... -
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- An Association Study of D9S158 Polymorphism(VNTR Marker Linked to the NMDA Receptor Gene) with korean Schizophrenics
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Yang BH, Park KK, Chung EK, Han JH, Kim JW, Choi IG, Lee YH, Kim GS, Chai YG
- KMID: 2340210
- J Korean Neuropsychiatr Assoc.
- 1998 Sep;37(5):974-982.
An association study with Korean schizophrenic patients(N=75) and normal controls(N=87) was performed to find the relationship between D9S158 polymorphism and schizophrenia using polymerase chain reaction. Eight different alleles of a... -
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- Proteomic Analysis of the Serum from Chicken Infected by Avian Influenza Virus
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Lee HT, Jung KH, Park JH, Ha GW, Oh YK, Oh JS, Chai YG
- KMID: 1449895
- J Bacteriol Virol.
- 2011 Sep;41(3):195-204.
- doi: 10.4167/jbv.2011.41.3.195
Avian influenza (AI) is an infectious, low pathogenic virus that is endemic all over the world and poses a potential threat to the poultry industry. Vaccination is a widely used... -
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- Neurobiological and Clinical Characteristics According to Lesch's Typology in Alcohol Dependence
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Choi MR, Chai YG, Lee BH, Lee JS
- KMID: 2250132
- Korean J Biol Psychiatry.
- 2011 Aug;18(3):109-118.
OBJECTIVES: Many studies have suggested different neurobiological findings and clinical courses in alcoholism. Recently, subtyping in alcohol dependence has become essential to overcome the heterogeneity of patients. Among several criteria... -
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- Detection of the Avian Influenza Viruses Nonstructural Protein 1 for Distinction between Vaccinated and Infected Chickens Using Synthetic Peptide-Based ELISA
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Lee HT, Jung KH, Park JH, Ha GW, Oh JS, Oh YK, Chai YG
- KMID: 2168585
- J Bacteriol Virol.
- 2010 Dec;40(4):207-212.
- doi: 10.4167/jbv.2010.40.4.207
Avian influenza (AI) virus infects both animal and human. Low pathogenic AI virus infections (some H7 and H9 subtypes) have been reported all over the world and pose a potential... -
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- TNF-alpha and IL-12 Secretion in Macrophages in Response to Spores of Bacillus anthracis Sterne
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Baek JJ, Jung KH, Chai YG
- KMID: 2055021
- J Bacteriol Virol.
- 2006 Sep;36(3):141-150.
- doi: 10.4167/jbv.2006.36.3.141
Baerobic, spore forming, and rod-shaped bacterium. Anthrax spores are introduced into macrophage by phagocytosis and multiply after germination. The anthrax spores infected in macrophage produce lethal toxin eventually caused cell... -
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- Association of Serotonin Transporter Gene Polymorphism with Alcohol Dependence
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Son HG, Choi IG, Chai YG, Choi MR, Kim JH, Yang BH, Kim SH, Sung SM
- KMID: 2202786
- J Korean Soc Biol Psychiatry.
- 2003 Nov;10(2):159-167.
OBJECTIVE: Under the hypothesis that 5-HTTLPR polymorphism plays some role in the susceptibility or vulnerability of some subgroup of alcohol dependence, associations of 5-HTTLPR polymorphism with alcohol dependence were examined.... -
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- Screening of Differentially Expressed Genes between PC12 Cells and A123.7 Cells
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Baik SY, Chai YG, Yang BH
- KMID: 2334593
- J Korean Soc Biol Psychiatry.
- 1999 Jul;6(1):67-73.
The cAMP-dependent protein kinase(PKA) is an intracellular enzyme with serine-threonine kinase activity that plays a key role in cell growth, differentiation, and apoptosis in eukaryotes. In order to understand the... -
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- Fluoxetine-induced Changes on Activity of Tryptophan Hydroxylase at RBL-2H3 Cells
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Baik SY, Jung KH, Choi MR, Yang BH, Kim SH, Choi IG, Chai YG
- KMID: 2286983
- Korean J Psychopharmacol.
- 2004 Dec;15(4):449-456.
OBJECTIVES: The aim of the present study is to explore the effect of fluoxetine on transcription, translation and activity of tryptophan hydroxylase (TPH), and intracellular level of serotonin. METHODS: The... -
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- Fluoxetine Increases the Expression of NCAM140 and pCREB in Rat C6 Glioma Cells
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Choi MR, Oh DH, Kim SH, Jung KH, Das ND, Chai YG
- KMID: 2316180
- Psychiatry Investig.
- 2012 Jun;9(2):180-186.
OBJECTIVE: Dysfunction of neural plasticity in the brain is known to alter neural networks, resulting in depression. To understand how fluoxetine regulates molecules involved in neural plasticity, the expression levels... -
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- Profiling of Proteins Regulated by Venlafaxine during Neural Differentiation of Human Cells
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Doh MS, Han DM, Oh DH, Kim SH, Choi MR, Chai YG
- KMID: 2316393
- Psychiatry Investig.
- 2015 Jan;12(1):81-91.
- doi: 10.4306/pi.2015.12.1.81
OBJECTIVE: Antidepressants are known to positively influence several factors in patients with depressive disorders, resulting in increased neurogenesis and subsequent relief of depressive disorders. To study the effects of venlafaxine... -
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