- The agonistic action of URO-K10 on Kv7.4 and 7.5 channels is attenuated by co-expression of KCNE4 ancillary subunit
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Lee JE, Park CH, Kang H, Ko J, Cho S, Woo J, Chae MR, Lee SW, Kim SJ, Kim J, So I
- KMID: 2507733
- Korean J Physiol Pharmacol.
- 2020 Nov;24(6):503-516.
- doi: 10.4196/kjpp.2020.24.6.503
KCNQ family constitutes slowly-activating potassium channels among voltage-gated potassium channel superfamily. Recent studies suggested that KCNQ4 and 5 channels are abundantly expressed in smooth muscle cells, especially in lower urinary... -
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- Onion peel extract and its constituent, quercetin inhibits human Slo3 in a pH and calcium dependent manner
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Wijerathne TD, Kim JH, Kim MJ, Kim CY, Chae MR, Lee SW, Lee KP
- KMID: 2455814
- Korean J Physiol Pharmacol.
- 2019 Sep;23(5):381-392.
- doi: 10.4196/kjpp.2019.23.5.381
Sperm function and male fertility are closely related to pH dependent K⺠current (KSper) in human sperm, which is most likely composed of Slo3 and its auxiliary subunit leucine-rich repeat-containing... -
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- Persistent Erectile Dysfunction after Discontinuation of 5-Alpha Reductase Inhibitor Therapy in Rats Depending on the Duration of Treatment
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Sung HH, Yu J, Kang SJ, Chae MR, So I, Park JK, Lee SW
- KMID: 2443240
- World J Mens Health.
- 2019 May;37(2):240-248.
- doi: 10.5534/wjmh.180082
PURPOSE: The current study is aimed to assess whether a longer duration of 5α-reductase inhibitor (5α-RI) exposure was associated with higher rate of permanent erectile dysfunction (ED) in a rat... -
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- Gene expression profile comparison in the penile tissue of diabetes and cavernous nerve injury-induced erectile dysfunction rat model
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Kam SC, Lee SH, Jeon JH, So I, Chae MR, Park JK, Lee SW
- KMID: 2426507
- Investig Clin Urol.
- 2016 Jul;57(4):286-297.
- doi: 10.4111/icu.2016.57.4.286
PURPOSE: To investigate the effects of cavernous nerve injury (CNI) on gene expression profiles in the cavernosal tissue of a CNI-induced erectile dysfunction (ED) model and to provide a basis... -
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