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Toxic Agents Affecting the Male Reproductive System

Cha YN

  • KMID: 1662640
  • J Korean Androl Soc.
  • 1987 Dec;5(1):5-20.
No abstract available.
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An Effect of Health Promotion Program in Mid-life Women

Kim KJ, Cha YN, Lim HK, Jang HS

  • KMID: 2297300
  • J Korean Acad Nurs.
  • 1999 Jun;29(3):541-550.
The purpose of the study was to test the effect of the health promotion program in middle women. The research design was a quasi experimental, nonequivalent control-group pretest-posttest design. The...
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Thiobenzamide S-oxidation in perfused rat liver: Ex vivo determination of hepatic flavin-containing monooxygenase activity

Chung WG, Roh HK, Cha YN

  • KMID: 1554770
  • Korean J Physiol Pharmacol.
  • 1997 Oct;1(5):591-595.
An ex vivo assay determining the flavin-containing monooxygenase (FMO) activity in perfused rat liver has been developed by assessing the rate of thiobenzamide S-oxide (TBSO) formation from the infused thiobenzamide (TB). The hepatotoxicity...
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Ethanol prevents from acetaminophen inducible hepatic necrosis by inhibiting its metabolic activation in mice

Lee SM, Cho TS, Cha YN

  • KMID: 1562330
  • Korean J Physiol Pharmacol.
  • 1998 Apr;2(2):261-269.
Concomitant administration of a single acute dose of ethanol (4 g/kg) protected mice from the hepatocellular injury observed upon administration of a large dose of acetaminophen (400 mg/kg). This was evidenced by the...
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An experimental Study on the Development of a Program for the Promotion of the Compliance with Sick Role Behavior in the Hypertensives

Choi BO, Cha YN, Jang HS, Kim YH

  • KMID: 1401876
  • J Nurs Acad Soc.
  • 1989 Apr;19(1):5-23.
This experimental study was undertaken to gauge the possibility of application and extension of a program for hypertension care to be operated by Community Health Practitioners. Four community health posts...
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Enhancement of O-dealkylation in Mouse Liver by Dietary Administrations of BHA and BHT: Studies with Isolated Perfused Livers and Hepatic Microsomes

Ji SC, Conway JG, Thurman RG, Cha YN

Effects of feeding 2(3)-tert-butyl 4-hydroxyanisole (BHA) and 3, 5-di-tert-butyl 4-hydroxytoluene (BHT) on the rates of mixed function oxidation and conjugation enzyme reactions have been determined using isolated hepatic microsomal fractions...
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Alteration of Substrate Specificity by Common Variants, E158K/E308G and V257M, in Human Hepatic Drug-metabolizing Enzyme, Flavin-containing Monooxygenase 3

Lee JK, Kang JH, Cha YN, Chung WG, Park CS

  • KMID: 2071590
  • Korean J Physiol Pharmacol.
  • 2003 Jun;7(3):157-162.
Our earlier studies found a significant correlation between the activities of ranitidine N-oxidation catalyzed by hepatic flavin-containing monooxygenase (FMO) and the presence of mutations in exon 4 (E158K) and exon...
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Enhancements of Mouse Hepatic Cytosol Enzyme Activities Involved in UDP-Glucuronic Acid Synthesis, Glutathione Reduction and Conjugation with Butylated Hydroxyanisole (BHA) and Its Structural Analogs

Cha YN, Chung JH, Heine HS, Hong SS

Activities of hepatic cytosol enzymes involved in UDP-g1ucuronic acid synthesis as well as in glutathione reduction and conjugation systems were determined following administrations of butylated hydroxyanisole (approximately 5 mmol/kg body...
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Correlation of the Serum Nitrate/Nitrite Level with the Severity of Biliary Tract Inflammation

Choi KH, Kim HS, Choi YS, Cho EH, Ahn SI, Lee KY, Hong KC, Choi SK, Hur YS, Kim SJ, Woo ZH, Shin SH, Cha SH, Cha YN

  • KMID: 1844199
  • J Korean Surg Soc.
  • 2004 Jul;67(1):55-59.
PURPOSE: The relationship between the biophysical and biochemical processes of gallbladder bile and nitric oxide is still not well known. In this study, the correlation between nitric oxide production and...
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Secondary Fish-Odor Syndrome Can be Acquired by Nitric Oxide-mediated Impairment of Flavin-containing Monooxygenase in Hepatitis B Virus-Infected Patients

Yi HG, Lee JN, Ryu SD, Kang JH, Cha YN, Park CS

  • KMID: 1611349
  • Korean J Physiol Pharmacol.
  • 2004 Aug;8(4):213-218.
Primary fish-odor syndrome (FOS) is a genetic disorder caused by defective flavin-containing monooxygenase 3 gene (FMO3) with deficient N-oxidation of trimethylamine (TMA), causing trimethylaminuria (TMAU). By contrast, secondary FOS can...
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Reduced Messenger RNA Expression of the Neuronal Nitric Oxide Synthase Gene in Infantile Hypertrophic Pyloric Stenosis

Hur MH, Seo JM, Cho EH, Yi HG, Park CS, Cha YN, Hong KC, Woo ZH

  • KMID: 2145276
  • J Korean Surg Soc.
  • 2000 Sep;59(3):391-396.
PURPOSE: Nitric oxide synthesized by neuronal nitric oxide synthase (nNOS) has been described as a mediator of smooth muscle relaxation in the mammalian gastrointestinal tract. Impaired expression of the nNOS...
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Assessment of flavin-containing monooxygenase (FMO) activity by determining urinary ratio of theobromine and caffeine in a Korean population after drinking a cup of coffee

Chung WG, Kang JH, Roh HK, Lee KH, Park CS, Cha YN

  • KMID: 1554144
  • Korean J Physiol Pharmacol.
  • 1999 Apr;3(2):207-213.
To examine individual variation in drug metabolism catalyzed by flavin-containing monooxygenase (FMO), 179 Korean volunteers' urinary molar concentration ratio of theobromine (TB) and caffeine (CA) was determined. Their urine was collected for 1...
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The Development of Health Promotion Programs for Middle Aged Women

Cha YN, Kim KJ, Lim HK, Jang HS, Han HS

  • KMID: 2329950
  • J Korean Community Nurs.
  • 1998 Jun;9(1):5-20.
The purpose of this study was to develop health promotion programs for middle aged women and to identify the adaptability and the effectiveness of the program in order to provide...
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