- Clinical response and safety of apatinib monotherapy in recurrent, metastatic cervical cancer after failure of chemotherapy:a retrospective study
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Xiao Y, Cheng H, Wang L, Yu X
- KMID: 2500401
- J Gynecol Oncol.
- 2020 Jan;31(1):e2.
- doi: 10.3802/jgo.2020.31.e2
Objective: To observe the safety and short-term efficacy of apatinib in the treatment of recurrent, metastatic cervical cancer in patients who have already received more than two kinds of comprehensive... -
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- A Case of Metastatic Adenocarcinoma of the Pleura from the Exocervix without Local Recurrence
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Kim YJ, Park SY, Kim YH, Choi CW, Yoo JH, Kang HM, Park MJ
- KMID: 2258888
- Korean J Med.
- 2011 Jun;80(Suppl 2):S199-S203.
It is very rare for an exocervical adenocarcinoma to metastasize to the lung parenchyma and pleura. A 54-year-old woman was admitted with dyspnea and left pleural effusion on chest X-ray.... -
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- The Role of HPV E6 and E7 Oncoproteins in HPV-associated Cervical Carcinogenesis
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Yim EK, Park JS
- KMID: 2166103
- Cancer Res Treat.
- 2005 Dec;37(6):319-324.
Cervical cancer is one of the leading world causes of cancer morbidity and mortality in woman, with more than 98% related to a human papillomavirus (HPV) infection origin. Infection with... -
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- Tetraarsenic Oxide-mediated Apoptosis in a Cervical Cancer Cell Line, SiHa
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Kim J, Bae SM, Lim DS, Kwak SY, Lee CK, Lee YS, Bae IJ, Yoo JY, Lee YJ, Kim CK, Ahn WS
- KMID: 2166121
- Cancer Res Treat.
- 2005 Oct;37(5):307-312.
PURPOSE: Diarsenic oxide, As2O3, has been reported to be effective in treating acute leukemia, and induce apoptosis in many tumor cells. In this study, the ability of a novel arsenical... -
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- Expression of Hypoxia Inducible Factor-1alpha in Invasive Squamous Cell Carcinoma of Uterine Cervix Treated by Radiotherapy
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Lee KJ, Cho MS, Kim SC, Moon HS, Park H, Lee SN, Sung SH, Shim KN, Lee KE, Jung SA, Yoo K, Park HY, Park SY, Yoo ES, Suh HS
- KMID: 1598228
- Korean J Pathol.
- 2005 Oct;39(5):307-312.
BACKGROUND: Hypoxia-inducible factor-1alpha (HIF-1alpha) is an intrinsic marker of tumor hypoxia, and this is associated with reduced radiosensitivity. Furthermore, HIF-1alpha can increase a tumor's aggressiveness by promoting neoangiogenesis, cell proliferation... -
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- Epstein-Barr Virus and p16INK4A Methylation in Squamous Cell Carcinoma and Precancerous Lesions of the Cervix Uteri
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Kim NR, Lin Z, Kim KR, Cho HY, Kim I
- KMID: 1712746
- J Korean Med Sci.
- 2005 Aug;20(4):636-642.
- doi: 10.3346/jkms.2005.20.4.636
Methylation of p16 is an important mechanism in cervical carcinogenesis. However, the relationship between cervical squamous cell carcinoma (SCC) and Epstein-Barr virus (EBV) remains controversial. Here, we explored whether EBV... -
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- Decreased expression of galectin-3 is associated with the progression of cervical neoplasia
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Lee JW, Song SY, Choi JJ, Choi CH, Lee JH, Kim BG, Bae DS
- KMID: 1979446
- Korean J Gynecol Oncol.
- 2005 Jun;16(2):97-103.
OBJECTIVE: Galectin-3, a member of the beta-galactoside-binding proteins, is an intracellular and extracellular lectin that interacts with intracellular glycoproteins, cell surface molecules and extracellular matrix proteins. Galectin-3 is expressed widely... -
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- Immunization with Adenoviral Vectors Carrying Recombinant IL-12 and E7 Enhanced the Antitumor Immunity against Human Papillomavirus 16-associated Tumor
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Park EK, Kim YW, Lee JM, NamKoong S, Kim DG, Chun HJ, Han BD, Bae SM, Jin HS, Sin JI, Ahn WS
- KMID: 1743357
- Cancer Res Treat.
- 2005 Feb;37(1):63-70.
PURPOSE: Human papillomavirus (HPV) infection has a significant role in cervical carcinogenesis, and HPV oncoprotein E7 plays an important part in the formation and maintenance of cervical cancer. Interleukin-12 (IL-12)... -
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- The Prognostic Effect of VEGF Expression in Squamous Cell Carcinoma of the Cervix Treated with Radiation Therapy Alone
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Kang JO, Hong SE
- KMID: 1733511
- J Korean Med Sci.
- 2004 Oct;19(5):693-697.
- doi: 10.3346/jkms.2004.19.5.693
We investigated the relationship between vascular endothelial growth factor (VEGF) expression and clinical outcome in squamous cell carcinoma of the cervix treated with radiotherapy alone. The immunohistochemical study was performed... -
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- A Prospective Randomized Study on Two Dose Fractionation Regimens of High-Dose-Rate Brachytherapy for Carcinoma of the Uterine Cervix: Comparison of Efficacies and Toxicities Between Two Regimens
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Nam TK, Ahn SJ
- KMID: 1785700
- J Korean Med Sci.
- 2004 Feb;19(1):87-94.
- doi: 10.3346/jkms.2004.19.1.87
To evaluate the toxicities and efficacies of two fractionation regimens of high-doserate brachytherapy in uterine cervical cancer, patients were stratified by stage Ib- IIa versus IIb-IVa, and randomly assigned to... -
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- Clinical Implications of VEGF and p53 Expression in Squamous Cell Carcinoma of the Cervix Treated with Radiation Therapy
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Kang JO, Hong SE, Kang DW
- KMID: 2166162
- Cancer Res Treat.
- 2003 Oct;35(5):440-444.
PURPOSE: The present study was designed to analyze the relationship between vascular endothelial growth factor (VEGF) and p53, and their impact on clinical outcome in squamous cell carcinoma of the... -
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- Alterations in Promoter Usage and Expression Levels of Insulin-like Growth Factor-II and H19 Genes in Cervical and Endometrial Cancer
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Lee C, Kim SJ, Na JY, Park CS, Lee SY, Kim IH, Oh YK
- KMID: 1972899
- Cancer Res Treat.
- 2003 Aug;35(4):314-322.
PURPOSE: The biallelic expression of insulin-like growth factor-II (IGF2) and H19 has been reported to be associated with the progression of several tumors. Here, the promoter usage and expression levels... -
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- Cell-Specific Growth Inhibition of Human Cervical Cancer Cell by Recombinant Adenovirus p53 in vitro and in vivo
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Bae SM, Kim YW, Yoon JH, Yoo JY, Seo YS, Nam SL, Lee JM, Namkoong S, Kim CK, Kim YW, Ahn WS
- KMID: 2166176
- Cancer Res Treat.
- 2003 Jun;35(3):181-190.
PURPOSE: Despite the significance of the p53 adenoviral vector in cancer gene therapy, an advanced strategy for the development of preferential tumor cell-specific delivery and the long-term persistent gene expression... -
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- Stromelysin-3 Expression in Squamous Intraepithelial Lesions and Invasive Squamous Cell Carcinoma of the Uterine Cervix
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Choi YD, Park EJ, Nam JH, Park CS
- KMID: 1725938
- Korean J Pathol.
- 2002 Dec;36(6):389-393.
BACKGROUND: Matrix metalloproteinase (MMP) plays an important role in the invasion and metastasis of epithelial neoplasms. Currently, detected stromelysin-3 (ST-3) (MMP-11) is thought to be associated with invasiveness in epithelial... -
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- Surgical Management of Recurrent Cervical Cancer
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Selman AE, Copeland L
- KMID: 1093951
- Yonsei Med J.
- 2002 Dec;43(6):754-762.
- doi: 10.3349/ymj.2002.43.6.754
The majority of patients with recurrent cervical cancer are incurable and treatment is based on the type of primary therapy delivered. Only a very small percentage of the patients with... -
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- Estimation of Joint Risks for Developing Uterine Cervix Cancer in Korea
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Yoon H, Shin A, Park SK, Jang MJ, Yoo KY
- KMID: 2283267
- Korean J Prev Med.
- 2002 Aug;35(3):263-268.
OBJECTIVE: This study was aiming at estimating the joint effects of various risk factors associated with uterine cervix cancer in Korea. METHODS: Data obtained from a case-control study were analyzed with... -
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- Sentinel Node Biopsy as an Indicator for Pelvic Nodes Dissection in Early Stage Cervical Cancer
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Rhim CC, Park JS, Bae SN, Namkoong S
- KMID: 1109760
- J Korean Med Sci.
- 2002 Aug;17(4):507-511.
- doi: 10.3346/jkms.2002.17.4.507
The purpose of this study was to investigate the feasibility of sentinel node frozen biopsy to minimize the extensive pelvic lymph nodes dissection in early stage cervical cancer patients on... -
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- Papillary Immature Metaplasia of the Uterine Cervix: a Report of 5 Cases with an Emphasis on the Differential Diagnosis from Reactive Squamous Metaplasia, High-Grade Squamous Intraepithelial Lesion and Papillary Squamous Cell Carcinoma
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Kang GH, Min K, Shim YH, Kim KR
- KMID: 648359
- J Korean Med Sci.
- 2001 Dec;16(6):762-768.
- doi: 10.3346/jkms.2001.16.6.762
Papillary immature metaplasia (PIM) is a distinctive exophytic lesion of the uterine cervix and shares some histologic and cytologic features with ordinary squamous metaplasia (SM), atypical immature squamous metaplasia (AIM),... -
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- Significance of p53 Immunoreactivity in Squamous Cell Carcinoma of the Cervix Treated with Radiotherapy Alone
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Ahn SJ, Choi HS, Choi C, Nah BS, Chung WK, Nam TK
- KMID: 2174984
- J Korean Cancer Assoc.
- 2001 Apr;33(2):106-112.
PURPOSE: We undertook this study to evaluate the significance of p53 immunoreactivity in squamous cell carcinoma of the cervix, treated with radiotherapy alone. MATERIALS AND METHODS: Immunohistochemical staining of p53 proteins... -
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- Results of Radio-thermotherapy in Stage IIIb Uterine Cervical Cancer Local response, survival rate and analysis of prognostic factor
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Moon CW
- KMID: 2007088
- J Korean Cancer Assoc.
- 2000 Aug;32(4):714-723.
PURPOSE: This retrospective study was conducted to obtain local response and survival rates, and to analyze prognostic factors affecting survival of patients treated with radio-thermotherapy for stage IIIb uterine cervical... -
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