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Compromised Cerebello-Thalamic White Matter Integrity in Medication-Free Patients With Obsessive-Compulsive Disorder

Lee W, Park H, Moon SY, Oh S, Lee J, Kim M, Kwon JS

Objective The cerebello-thalamic tract is the only efferent white matter (WM) bundle of the cerebellum that connects the cerebellum to the thalamus and has recently attracted much attention in obsessive-compulsive...
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mGluR1 Regulates the Interspike Interval Threshold for Dendritic Ca2+ Transients in the Cerebellar Purkinje Cells

Jang DC, Ryu C, Chung G, Kim SK, Kim SJ

Ca2+ transients can be observed in the distal dendrites of Purkinje cells (PCs) despite their lack of action potential backpropagation. These Ca2+ events in distal dendrites require specific patterns of PC...
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Cerebellar Structural Abnormality in Autism Spectrum Disorder: A Magnetic Resonance Imaging Study

Lu Q, Chen J, Wang Y, Huang L, Jiang Z, Nguchu BA, Chen S, Qiu B, Wang X

Objective This study uses structural magnetic resonance imaging to explore changes in the cerebellar lobules in patients with autism spectrum disorder (ASD) and further analyze the correlation between cerebellar structural...
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Cerebellar Gray Matter Volume and its Role in Executive Function, and Attention: Sex Differences by Age in Adolescents

Kim H, Park B, Kim SY, Kim J, Kim B, Jung KI, Lee SY, Hyun Y, Kim BN, Park S, Park MH

Objective: This research measures the regional GMV (rGMV) of the cerebellum, attention, Executive Function (EF) and we aimed to identify their correlation and sex differences in children and adolescents. Methods: Subjects...
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Anatomic and Physiologic Properties and Clinical Manifestations ofVestibulo-Autonomic Reflexes

Lee JY, Choi JY

The vestibular nervous system senses linear and angular acceleration upon the head during postural change and generates vestibular nerve activity changes. The autonomic nervous system regulates involuntary physiologic processes throughout...
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Generation of Astrocyte-Specific MAOB Conditional Knockout Mouse with Minimal Tonic GABA Inhibition

Lee JM, Sa M, An H, Kim JMJ, Kwon J, Yoon BE, Lee CJ

  • KMID: 2531119
  • Exp Neurobiol.
  • 2022 Jun;31(3):158-172.
  • doi: 10.5607/en22016
Monoamine oxidase B (MAOB) is a key enzyme for GABA production in astrocytes in several brain regions. To date, the role of astrocytic MAOB has been studied in MAOB null...
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Time Course of Remote Neuropathology Following Diffuse Traumatic Brain Injury in the Male Rat

Giordano KR, Law LM, Henderson J, Rowe RK, Lifshitz J

  • KMID: 2530368
  • Exp Neurobiol.
  • 2022 Apr;31(2):105-115.
  • doi: 10.5607/en21027
Traumatic brain injury (TBI) can affect different regions throughout the brain. Regions near the site of impact are the most vulnerable to injury. However, damage to distal regions occurs. We...
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Paraneoplastic Cerebellar Degeneration Presented as Acute Vertigo

Kim SH

Paraneoplastic cerebellar degeneration is a rare neurological manifestation of nonmetastatic malignancy. Its usual manifestation is subacute to chronic dizziness, gait ataxia, and dysarthria. There have been only a few cases...
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Muscular and collagenous cerebellar choristoma in a dog

Ripplinger A, Melo SMPd, Ferrarin DA, Schwab ML, Wrzesinski MR, Rauber JdS, Flores MM, Kommers GD, Mazzanti A

This report aims to describe the first case of muscular and collagenous choristoma in a dog. A 10-yr-old female mixed-breed dog presented with lateral recumbence, vocalization, positional vertical nystagmus, divergent...
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Mega cisterna magna in bipolar mood disorder: a case report

Yazici E, Kose S, Gunduz Y, Kurt EM, Yazici AB

Mega cisterna magna (MCM), one of the members of the Dandy-Walker complex, is a developmental malformation of the posterior fossa that is larger than 10 mm but morphologically does not...
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Posterior Fossa Teratomas in Adults : A Systematic Review

Shin DW, Kim JH, Song SW, Kim YH, Cho YH, Hong SH, Nam SJ

Objective : The occurrence of posterior fossa teratomas in adulthood is extremely rare. In this study, we aimed to report our experience with two cases of posterior fossa mature teratoma...
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Understanding Vestibular Information Processing in Velocity-Storage Circuit and Application to Interpreting Clinical Manifestation of Vestibular Disorders

Choi JY

The velocity-storage circuit comprised of bilateral vestibular nucleus complexes, commissural fiber, and nodulus and uvula functions in refining the raw vestibular signal to estimate rotational velocity, gravity direction, and inertia....
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Increases in GFAP immunoreactive astrocytes in the cerebellar molecular layer of young adult CBA/J mice

Tyszkiewicz C, Pardo ID, Ritenour HN, Liu CN, Somps C

Background: CBA/J mice are standard experimental animals in auditory studies, and age-related changes in auditory pathways are well documented. However, changes in locomotion-related brain regions have not been systematically explored. Results:...
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The Role of Thyroid Hormone in the Regulation of Cerebellar Development

Ishii S, Amano I, Koibuchi N

The proper organized expression of specific genes in time and space is responsible for the organogenesis of the central nervous system including the cerebellum. The epigenetic regulation of gene expression...
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Cell Type-specific Knockout with Gli1-mediated Cre Recombination in the Developing Cerebellum

Choi JM, Acharya R, Marasini S, Narayan B, Lee KW, Hwang WS, Chang DY, Kim SS, Kim HS

  • KMID: 2517473
  • Exp Neurobiol.
  • 2021 Jun;30(3):203-212.
  • doi: 10.5607/en21017
The inducible Cre-loxP system provides a useful tool for inducing the selective deletion of genes that are essential for proper development and enables the study of gene functions in properly...
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Cerebellar Glioependymal Cyst

Kim E

Glioependymal cyst (GEC) is an uncommonly observed clinical entity in the posterior cranial fossa. A 36-year-old female with cystic lesion in the right cerebellum was hospitalized for evaluating headache and...
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Anterior Inferior Cerebellar Artery Dissection Diagnosed by Conventional Magnetic Resonance Imaging

Kim YS, Shin BS, Kang HG

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Mirogabalin: could it be the next generation gabapentin or pregabalin?

Kim JY, Abdi S, Huh B, Kim KH

Except for carbamazepine for trigeminal neuralgia, gabapentinoid anticonvulsants have been the standard for the treatment of neuropathic pain. Pregabalin, which followed gabapentin, was developed with the benefit of rapid peak...
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Neurotological Findings in a Patient with Glufosinate Ammonium Intoxication

Kim JY, Ham JY, Jeong SH

The upward deviation could be explained by loss of inhibitory inputs from the cerebellum onto the brainstem anterior semicircular canal projections for upward vestibulo-ocular reflex, which would lead to an...
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Inhibitory potentials of Cymbopogon citratus oil against aluminium-induced behavioral deficits and neuropathology in rats

Temitayo GI, Olawande B, Emmanuel YO, Timothy AT, Kehinde O, Susan LF, Ezra L, Joseph OO

Cymbopogon citratus is a tropical phytomedicinal plant that is widely known for its hypoglycemic, hypolipidemic, anxiolytic, sedative, antioxidative and anti-inflammatory properties. In this study, we have examined the neuroprotective effects...
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