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Antibacterial effect of different concentrations of Galla Chinensis extract on cariogenic bacteria in a biofilm model

Kim EJ, Jin BH

OBJECTIVES: Galla chinensis inhibited the adherence of planktonic oral bacteria and acid production by cariogenic bacteria. However, little is known about the relevant conditions of Galla Chinensis extract (GCE) exposure...
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Antimicrobial effect of toothbrush with light emitting diode on dental biofilm attached to zirconia surface: an in vitro study

Park JH, Kim YG, Um HS, Lee SY, Lee JK, Chang BS

PURPOSE: The purpose of this study was to evaluate the antimicrobial effects of a toothbrush with light-emitting diodes (LEDs) on periodontitis-associated dental biofilm attached to a zirconia surface by static...
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Bacillus Calmette-Guérin (BCG)-Cell Wall Skeleton as Immunotherapeutic Option for BCG-Refractory Superficial Bladder Cancer

Whang YM, Yoon DH, Hwang GY, Choi YW, Chang IH

Although intravesical instillation of Mycobacterium bovis bacillus Calmette-Guérin (BCG) is the most successful cancer immunotherapy for superficial bladder cancer, the serious side effects are frequently arisen by using live mycobacteria....
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Heat-Killed Saccharomyces cerevisiae, A Dectin-1 Agonist, Selectively Induces IgG4 Production by Human B Cells

Park HY, Yoon HK, Kim JY, Park SR

Dectin-1 is a major receptor that recognizes fungal cell wall β-glucan. We previously reported that heat-killed Saccharomyces cerevisiae (HKSC), a Dectin-1 agonist, selectively induces IgG1 class switching in mouse B...
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Galla chinensis extracts and calcium induce remineralization and antibacterial effects of enamel in a Streptococcus mutans biofilm model

Kim EJ, Jin BH

OBJECTIVES: The purpose of this study was to investigate the combined effects of Galla chinensis extract (GCE) and calcium (CA) on enamel remineralization. The antibacterial effect of G. chinensis on...
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Adenine attenuates lipopolysaccharide-induced inflammatory reactions

Silwal P, Lim K, Heo JY, Park JI, Namgung U, Park SK

A nucleobase adenine is a fundamental component of nucleic acids and adenine nucleotides. Various biological roles of adenine have been discovered. It is not produced from degradation of adenine nucleotides...
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Screening and Evaluation of Streptomyces Species as a Potential Biocontrol Agent against a Wood Decay Fungus, Gloeophyllum trabeum

Jung SJ, Kim NK, Lee DH, Hong SI, Lee JK

Two-hundred and fifty-five strains of actinomycetes isolated from soil samples were screened for their antagonistic activities against four well-known wood decay fungi (WDF), including a brown rot fungus, Gloeophyllum trabeum...
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Mon1 Is Essential for Fungal Virulence and Stress Survival in Cryptococcus neoformans

Son YE, Jung WH, Oh SH, Kwak JH, Cardenas M, Park HS

Mon1 is a guanine nucleotide exchange factor subunit that activates the Ypt7 Rab GTPase and is essential for vacuole trafficking and autophagy in eukaryotic organisms. Here, we identified and characterized...
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Efficacy of an LED toothbrush on a Porphyromonas gingivalis biofilm on a sandblasted and acid-etched titanium surface: an in vitro study

Lee H, Kim YG, Um HS, Chang BS, Lee SY, Lee JK

PURPOSE: The aim of this study was to evaluate the antimicrobial effect of a newly devised toothbrush with light-emitting diodes (LEDs) on Porphyromonas gingivalis attached to sandblasted and acid-etched titanium...
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Chemical Composition and Antimicrobial Efficacy of Helminthostachys zeylanica against Foodborne Bacillus cereus

Yenn TW, Ring LC, Zahan KA, Abdul Rahman MS, Tan WN, Shaik Alaudin BJ

Helminthostachys zeylanica is a rare plant grows in lightly shaded areas. The fern was traditionally used as antipyretic and antiphlogistic agents. This study was aimed to evaluate the antibacterial potential...
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Role of MAPK Signaling Pathways in Regulating the Hydrophobin Cryparin in the Chestnut Blight Fungus Cryphonectria parasitica

So KK, Kim DH

We assessed the regulation of cryparin, a class II hydrophobin, using three representative mitogen-activated protein kinase (MAPK) pathways in Cryphonectria parasitica. Mutation of the CpSlt2 gene, an ortholog of yeast...
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Protection of the brain through supplementation with larch arabinogalactan in a rat model of vascular dementia

Lim SH, Lee J

BACKGROUND/OBJECTIVES: Vascular dementia (VaD) caused by reduced blood supply to the brain manifests as white matter lesions accompanying demyelination and glial activation. We previously showed that arabinoxylan consisting of arabinose...
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Intestinal Microbiota Contributes to Energy Balance, Metabolic Inflammation, and Insulin Resistance in Obesity

Cavallari , Schertzer

Obesity is associated with increased risk of developing metabolic diseases such as type 2 diabetes. The origins of obesity are multi-factorial, but ultimately rooted in increased host energy accumulation or...
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Acid-Fastness of Histoplasma in Surgical Pathology Practice

Rajeshwari M, Xess I, Sharma MC, Jain D

BACKGROUND: Histoplasmosis (HP) is diagnosed by visualizing intracellular microorganisms in biopsy and/or culture. Periodic-acid Schiff (PAS) and Gomori methenamine silver (GMS) staining methods are routinely used for identification. The acid-fast...
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Changes in serum levels of lipopolysaccharides and CD26 in patients with Crohn's disease

Magro DO, Kotze PG, Martinez C, Camargo MG, Guadagnini D, Calixto AR, Vasques AC, Ayrizono M, Geloneze B, Pareja JC, Saad MJ, Coy CS

BACKGROUND/AIMS: Lipopolysaccharide (LPS) is a molecule formed by lipids and polysaccharides and is the major cell wall component of gram-negative bacteria. High LPS levels are known to block CD26 expression...
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The Role of IL-17 in a Lipopolysaccharide-Induced Rhinitis Model

Bae JS, Kim JH, Kim EH, Mo JH

PURPOSE: Lipopolysaccharide (LPS) is a cell wall component of Gram-negative bacteria and important for pro-inflammatory mediators. This study aimed to establish a rhinitis model using ovalbumin (OVA) and LPS in...
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Cryptococcus Species Infection in a Bone Marrow Transplant Patient and Review of the Literature

Kim YH, Park YM, Lee JY, Lee JH

Cryptococcosis is caused by several Cryptococcus species, including C. neoformans and C. gattii. Skin involvement is seen in 10~20% of systemic cryptococcosis. There are also rare cases of primary cutaneous...
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An Effective Method of RNA Extraction from Mycobacterium tuberculosis

Oh TS, Kang HY, Nam YS, Kim YJ, You EK, Lee MY, Cho SY, Lee HJ

In the RNA-based study, it is important to extract high-quality RNA. However, RNA extraction from Mycobacterium tuberculosis is problematic due to its thick, waxy cell wall rich in mycolic acid,...
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Evaluation of Dual-Color Fluorescence In Situ Hybridization With Peptide Nucleic Acid Probes for the Detection of Mycobacterium tuberculosis and Non-Tuberculous Mycobacteria in Clinical Specimens

Kim N, Lee SH, Yi J, Chang CL

BACKGROUND: Peptide nucleic acid (PNA) probes are artificial DNA analogues with a hydrophobic nature that can penetrate the mycobacterial cell wall. We evaluated a FISH method for simultaneous detection and...
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Current Technologies and Related Issues for Mushroom Transformation

Kim S, Ha BS, Ro HS

Mushroom transformation requires a series of experimental steps, including generation of host strains with a desirable selective marker, design of vector DNA, removal of host cell wall, introduction of foreign...
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