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An Experimental Model of Hepatic Fibrosis Induced by Alcohol and CCl4: Can the Lipopolysaccharide Prevent Liver Injury Induced by Alcohol and CCl4?

Chae HB, Jang LC, Park SM, Son BR, Sung R, Choi JW

  • KMID: 1123167
  • Korean J Hepatol.
  • 2002 Jun;8(2):173-178.
BACKGROUND/AIMS: It is well known that alcohol enhances the toxicity of CCl4. We tried to establish an alcoholic liver cirrhosis model by administration of alcohol and CCl4 to rats. We...
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Relationship of Propranolol Pharmacokinetic Parameters with Portosystemic Shunt in CCl4-induced cirrhotic Rats

Koh DH, Park GT, Kim JM, Yun YS, Lee SH, Kim DU, Kim JB, Choi YY, Kang JS, Choi HS, Hahm JS, Lee MH

  • KMID: 863098
  • Korean J Hepatol.
  • 2002 Sep;8(3):277-287.
BACKGROUND: This study was designed to determine the relationship of propranolol pharmacokinetic parameters with portosystemic shunt in CCl4-induced cirrhotic rats. METHODS: Cirrhotic rats(n=6) were induced by intramuscular injection of...
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