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A positive feedback loop of heparanase/ syndecan1/nerve growth factor regulates cancer pain progression

Su X, Wang B, Zhou Z, Li Z, Tong S, Chen S, Zhang N, Liu S, Zhang M

Background: The purpose of this research was to assess the role of heparanase (HPSE)/syndecan1 (SDC1)/nerve growth factor (NGF) on cancer pain from melanoma. Methods: The influence of HPSE on the biological...
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Management of Physical Symptoms in Patients with Advanced Cancer during the Last Weeks and Days of Life

Azhar A, Hui D

Patients with advanced cancer are faced with many devastating symptoms in the last weeks and days of life, such as pain, delirium, dyspnea, bronchial hypersecretions (death rattle) and intractable seizures....
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Survey of Opioid Risk Tool Among Cancer Patients Receiving Opioid Analgesics

Oh SY, Park K, Koh SJ, Kang JH, Chang MH, Lee KH

Background: The risk of opioid-related aberrant behavior (OAB) in Korean cancer patients has not been previously evaluated. The purpose of this study is to investigate the Opioid Risk Tool (ORT)...
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Splanchnic nerve neurolysis via the transdiscal approach under fluoroscopic guidance: a retrospective study

Cai Z, Zhou X, Wang M, Kang J, Zhang M, Zhou H

Background: Neurolytic celiac plexus block (NCPB) is a typical treatment for severe epigastric cancer pain, but the therapeutic effect is often affected by the variation of local anatomical structures induced...
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Adverse Effects of Opioids and Safe Prescription for Chronic Non-Cancer Pain

Lee JC, Chang DJ, Song HJ

Chronic non-cancer pain (CNCP) affects approximately 20% of the general population and its global prevalence is increasing. CNCP affects the quality of life (QOL) of both the patients and their...
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The effects of ketamine on pain control in stage IV cancer patients receiving palliative care

Kim S, Kang J, Choi J, Kong E

Background: We evaluated the effects of intravenous ketamine on cancer pain in stage IV cancer patients receiving palliative care. Methods: In total, 253 stage IV cancer patients with cancer pain hospitalized...
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Factors Influencing Oncology Nurses’ Pain Management of Cancer Patients

Seo HS, Park EY, Park SJ, Han BR, Jang MJ

Purpose: The purpose of this study is to investigate the factors influencing oncology unit nurses’ pain management of cancer patients. Methods: This study was a designed descriptive correlation study. The...
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Pain Assessment of Lung Cancer Patients in the Emergency Department: A Case Report

Youn N

This case report aims to emphasize the importance of a differential diagnosis when patients complain about pain. Although pain is one of cancer patients’ most common physical symptoms, not all...
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Factors associated with successful response to neurolytic celiac plexus block in patients with upper abdominal cancer-related pain: a retrospective study

Kwon HJ, Jang K, Leem JG, Shin JW, Kim DH, Choi SS

Background: Prior studies have reported that 40%-90% of the patients with celiac plexus-mediated visceral pain benefit from the neurolytic celiac plexus block (NCPB), but the predictive factors of response to...
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Pain-related Prescribing Patterns and Associated Factor in Breast Cancer Patients

Lee J, Park IB, Seo HJ

Background: With an increase in the number of breast cancer survivors, greater importance is attached to health-related quality of life, particularly pain and symptom control. This study aimed to identify...
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Comeback of ketamine: resurfacing facts and dispelling myths

Kumar A, Kohli A

Initially known as CI-581, ketamine was first synthesized in 1962 as a replacement from phencyclidine. It has since been used as an anesthetic and analgesic. In addition, it has bronchodilating,...
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Celiac Plexus Neurolysis for the Treatment of Patients with Terminal Cancer at a Tertiary University Hospital in Korea

Byeon GJ, Park JY, Choi YM, Ri HS, Yoon JU, Choi EJ

Purpose: The aim of this study was to investigate celiac plexus neurolysis (CPN) for the treatment of cancerous upper abdominal pain in a tertiary university hospital in Korea. Methods: At the...
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Differences in nurses’ perceptions of self-reported pain and the administered morphine dose according to the patient’s facial expression in Korea

Park JY, Lee DI

Purpose: This study aimed to compare nurses’ perceptions of self-reported pain, the recorded pain score, and pain treatment according to the patient’s facial expression. Methods: In this descriptive cross-sectional survey, the...
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The Effect of Trigger Point Injections on Pain in Patients with Advanced Cancer

Lee CY, Kim EJ, Hwang DG, Jung MY, Cho HG

BACKGROUND: It has been reported that in 62.5% of cases of incurable cancer pain, the complaint is due to myofascial pain syndrome. Trigger point injections using dibucaine hydrochloride help patients...
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Prescribing Opioids for Chronic Pain

Yoon DU, Kang UG

Opioids are effective analgesics, but they are often difficult to use properly, due mainly to adverse events, such as constipation, respiratory depression, addiction, tolerance, and opioid induced hyperalgesia. In the...
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The Effect of Cervical Stellate Ganglion Block Using Botulinum Toxin Type A in Intractable Cancer-related Pain: Case Report

Sohn D, Park GY, Im S, Jeon SH, Choi Y

OBJECTIVE: For patients who do not relieve with pharmacological intervention, interventional treatment including neurolytic blocks may have a specific role in palliative cancer management. METHOD: We performed cervical stellate ganglion block...
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Successful Treatment with Transdermal Buprenorphine Patch in Opioid-Dependent Cancer Patients: Case Series

Go SI, Kim JH, Lee GW, Kang JH

Opioid aberrant behavior is an emerging problem as strong opioid is increasingly used to alleviate cancer pain in patients with cancer. Although the treatment of opioid addiction and physical dependence...
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Overview of the Management of Chronic Non-Cancer Pain in Patients with Spinal Disease

Shin HK, Nam WD, Kim DS, Kim JH, Kim SK, Ahn TK, Kim SS

STUDY DESIGN: Cross-sectional, multi-center survey study. OBJECTIVES: The objective of this study was to investigate the pain status, pain management methods, and pain experience after treatment among patients suffering from chronic...
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Medical Treatment of Cancer Pain: Drug Therapy according to Guidelines Will Improve the Quality of Life of Cancer Patients

Bae SB, Lee SC

Cancer pain is the most common and troublesome symptom for cancer patients. The more the cancer patient gets to the end of the life, the worse the pain. There are...
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Factors Influencing Pain Medication Preference for Breakthrough Cancer Patients and Their Application to Treatments: Survey on Physicians

Shin J, Shim JY, Seo MS, Kim DY, Lee J, Hwang IG, Baek SK, Choi YS

PURPOSE: The purpose of this study was to assess the factors influencing the rescue medication decisions for breakthrough cancer patients and evaluate treatments using the factors. METHODS: Based on the results...
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